Zobrazeno 1 - 8
of 8
pro vyhledávání: '"John Albeck"'
Publikováno v:
STAR Protocols, Vol 3, Iss 4, Pp 101752- (2022)
Summary: Here, we describe a protocol for modulating the dynamics of the extracellular signal-regulated kinases (ERK) pathway in a customized alternating current (AC) electric field stimulation chamber. We use an ERK translocation reporter that can a
Externí odkaz:
https://doaj.org/article/3a52c2d254d248be9c8ad8af185c0aed
Autor:
Liang Guo, Kan Zhu, Michael Pargett, Adam Contreras, Patrick Tsai, Quan Qing, Wolfgang Losert, John Albeck, Min Zhao
Publikováno v:
iScience, Vol 24, Iss 11, Pp 103240- (2021)
Summary: Intracellular signaling dynamics play fundamental roles in cell biology. Precise modulation of the amplitude, duration, and frequency of signaling activation will be a powerful approach to investigate molecular mechanisms as well as to engin
Externí odkaz:
https://doaj.org/article/1d7951c8fef84b53b75c23fe71a219f8
Autor:
Anastasia L. Berg, Megan R. Showalter, Nont Kosaisawe, Michelle Hu, Nathanial C. Stephens, Michael Sa, Hailey Heil, Noemi Castro, Jenny J. Chen, Kacey VanderVorst, Madelyn R. Wheeler, Zachary Rabow, Tomas Cajka, John Albeck, Oliver Fiehn, Kermit L. Carraway
Publikováno v:
Cancer Letters. 557:216090
Autor:
Jangir, Selimkhanov, Brooks, Taylor, Jason, Yao, Anna, Pilko, John, Albeck, Alexander, Hoffmann, Lev, Tsimring, Roy, Wollman
Publikováno v:
Science (New York, N.Y.). 346(6215)
Stochasticity inherent to biochemical reactions (intrinsic noise) and variability in cellular states (extrinsic noise) degrade information transmitted through signaling networks. We analyzed the ability of temporal signal modulation--that is, dynamic
Autor:
Masoud, Mojaza, Michael John, Albeck
Publikováno v:
Ugeskrift for laeger. 167(17)
Autor:
Michael John, Albeck, Torben, Bøge-Rasmussen, Ole, Fedders, Carsten Juul, Nielsen, Jesper, Lundberg
Publikováno v:
Ugeskrift for laeger. 167(12-13)
Autor:
Michael John, Albeck
Publikováno v:
Ugeskrift for laeger. 165(45)
Publikováno v:
Cancer Research. 72:PR7-PR7
The growth factor signaling network, including the Akt, ERK, mTOR and other pathways, is deregulated in many diseases and is a prominent target for therapeutic inhibitors. The effectiveness of these inhibitors is limited by the existence of homeostat