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of 7
pro vyhledávání: '"John A. Zadroga"'
Autor:
Yating Wang, Brea Tinsley, Stefano Spolitu, John A. Zadroga, Heena Agarwal, Amesh K. Sarecha, Lale Ozcan
Publikováno v:
Journal of Lipid Research, Vol 65, Iss 3, Pp 100515- (2024)
LDL-C lowering is the main goal of atherosclerotic cardiovascular disease prevention, and proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibition is now a validated therapeutic strategy that lowers serum LDL-C and reduces coronary events. Ir
Externí odkaz:
https://doaj.org/article/cdbd640c0ee44d50846353620dba90c7
Autor:
Ziyu Zhang, Wen Dai, Shuwei Weng, Mengdie Luo, Jiahao Fu, John A. Zadroga, Stefano Spolitu, Daoquan Peng
Publikováno v:
Lipids in Health and Disease, Vol 19, Iss 1, Pp 1-7 (2020)
Abstract Background Non-alcoholic fatty liver disease (NAFLD) is currently the major cause of chronic liver disease globally. Bile acids (BAs) have emerged as relevant signaling molecules that are associated with NAFLD development. This study was aim
Externí odkaz:
https://doaj.org/article/b289adbc4520450b87ff9adb08111737
Autor:
John A. Zadroga, Vanajakshi Mogulla, Christopher Grant, Djordje Jevtic, Andrew Virata, Igor Dumic
Publikováno v:
Case Reports in Infectious Diseases, Vol 2021 (2021)
Leukocytoclastic vasculitis is a rare form of immune-mediated vasculitis that might be caused by infections or autoimmune diseases or might be precipitated by specific medications. We describe a 65-year-old patient, who was receiving vancomycin for a
Externí odkaz:
https://doaj.org/article/00c7d44397f6402fb117a50718249dc0
Autor:
John D. Douglass, Yin Xiu Zhou, Amy Wu, John A. Zadroga, Angela M. Gajda, Atreju I. Lackey, Wensheng Lang, Kristen M. Chevalier, Steven W. Sutton, Sui-Po Zhang, Christopher M. Flores, Margery A. Connelly, Judith Storch
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 3, Pp 717- (2019)
Externí odkaz:
https://doaj.org/article/958579d899004c369825ee7df8364455
Publikováno v:
Cell reports. 40(8)
SUMMARYExcessive hepatic glucose production contributes to the development of hyperglycemia and is a key feature of type 2 diabetes. Here, we report that activation of hepatic Rap1a suppresses gluconeogenic gene expression and glucose production, whe
Autor:
Christopher Grant, John A. Zadroga, Andrew R Virata, Vanajakshi Mogulla, Igor Dumic, Djordje Jevtic
Publikováno v:
Case Reports in Infectious Diseases
Case Reports in Infectious Diseases, Vol 2021 (2021)
Case Reports in Infectious Diseases, Vol 2021 (2021)
Leukocytoclastic vasculitis is a rare form of immune-mediated vasculitis that might be caused by infections or autoimmune diseases or might be precipitated by specific medications. We describe a 65-year-old patient, who was receiving vancomycin for a
Publikováno v:
Current Opinion in Lipidology. 30:186-191
Purpose of reviewThe purpose of this review is to highlight the recent findings of one of the most promising therapeutic targets in LDL cholesterol (LDL-C) management, proprotein convertase subtilisin/kexin type 9 (PCSK9).Recent findingsEndoplasmic r