Zobrazeno 1 - 10
of 30
pro vyhledávání: '"John A. Quest"'
Publikováno v:
Mutation Research/Reviews in Genetic Toxicology. 297:197-233
Parties interested in registering a pesticide chemical with the U.S. Environmental Protection Agency's (USEPA's) Office of Pesticide Programs (OPP) must submit toxicity information to support the registration. Mutagenicity data are a part of the requ
Publikováno v:
Japanese Journal of Cancer Research : Gann
Short-term and long-term carcinogenicity of methyl carbamate (MCB) was evaluated in F344 rats and B6C3F1 mice. In experiments lasting 6, 12, and 18 months, MCB was given in water by gavage to groups of 10 male and 10 female rats at 0 or 400 mg/kg bod
Publikováno v:
Regulatory Toxicology and Pharmacology. 14:3-11
Aliette, a fungicide compound, was evaluated for carcinogenic potential by the Health Effects Division of the Office of Pesticide Programs using a consensus peer review process and EPA's guidelines for risk assessment. Aliette was categorized as a gr
Publikováno v:
Journal of Cardiovascular Electrophysiology. 2:s114-s123
CNS Control of Cardiac Rhythm. The purpose of our studies was to determine brain areas that influence cardiac rhythm. Studies were performed in anesthetized cats and indicate that a yet undetermined site in the hindbrain involving GABAergic mechanism
Autor:
Penelope A. Fenner-Crisp, Reto Engler, Esther Rinde, Marion P. Copley, Karen Hamernik, William L. Burnam, Bernice Fisher, John A. Quest
Publikováno v:
Regulatory Toxicology and Pharmacology. 12:117-126
The carcinogenic potential of methidathion, a dimethoxyorganic phosphorus pesticide and cholinesterase inhibitor, was evaluated by the Health Effects Division of the Office of Pesticide Programs using a consensus peer review process and the EPA's gui
Autor:
R.J. Whiting, Reto Engler, Penelope A. Fenner-Crisp, Marion P. Copley, William L. Burnam, Kerry L. Dearfield, John A. Quest, Karen Hamernik, D.S. Saunders
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 17(1)
The Health Effects Division of the Office of Pesticide Programs (OPP) assessed the carcinogenic potential of three structurally related chloroalkylthiodicarboximide fungicides using a consensus peer review process and EPA's 1986 guidelines for cancer
Publikováno v:
Environmental Health Perspectives
The United States Environmental Protection Agency's Office of Pesticide Programs (OPP) requires that data from toxicity testing be submitted to the OPP to support the registration of pesticide chemicals. Once the toxicity data are submitted, they are
Publikováno v:
Toxicology and Applied Pharmacology. 44:653-656
The effect of polyethylene glycol 400 (PEG-400), dimethylsulfoxide (DMSO), and dimethylformamide (DMF) on cardiac rhythm of cats intoxicated with deslanoside was studied. The former two solvents exerted no deleterious cardiac rhythm effects. However,
Publikováno v:
Journal of Applied Physiology. 62:2264-2272
The aim of this study was to evaluate the cardiorespiratory effects of intravenously administered gamma-aminobutyric acid (GABA) alpha-(4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridin-3-ol, THIP) and beta-(baclofen) receptor agonists and to locate the site
Autor:
R. K. Browne, Richard A. Gillis, John A. Quest, N. Anastasi, K. L. Dretchen, J. Dias Souza, K. Hill, I J Namath
Publikováno v:
Journal of Cardiovascular Pharmacology. 9:103-109
The purposes of our study were to determine the contribution of the CNS to the hypotensive effect of urapidil in the cat and the specific brain site of action of this agent. For the first purpose, urapidil was studied on preganglionic sympathetic ner