Výsledky vyhledávání - "John A. Moyer"

Akademický článek

TRPV1 antagonist JNJ-39439335 (mavatrep) demonstrates proof of pharmacology in healthy men: a first-in-human, double-blind, placebo-controlled, randomized, sequential group study

Autor: Prasarn Manitpisitkul, Michael Brandt, Christopher M. Flores, Velga Kenigs, John A. Moyer, Gary Romano, Kevin Shalayda, Arthur J. Mayorga

Publikováno v: PAIN Reports, Vol 1, Iss 4, p e576 (2016)

Abstract. This double-blind, randomized, placebo-controlled, sequential group, phase 1 study was designed to assess in healthy men, the safety, tolerability, pharmacokinetics, and translational pharmacodynamics of JNJ-39439335 (mavatrep), a transient

Externí odkaz: https://doaj.org/article/e5d8331f05dd486285cf40982c6c5af0

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Akademický článek

The LieCal Project and Its Investigation of Problem-Solving Strategies as a Measure of Longitudinal Curricular Effects on Students’ Learning

Autor: Jinfa Cai, Steven Silber, Stephen Hwang, Bikai Nie, John C. Moyer, Ning Wang

Publikováno v: REMATEC. Revista de Matemática, Ensino e Cultura, Vol 11, Iss 21 (2016)

This paper presents a summary of the important middle school findings from the LieCal Project (Longitudinal Investigation of the Effect of Curriculum on Algebra Learning) and examines in detail the longitudinal effects of a middle school reform mathe

Externí odkaz: https://doaj.org/article/a8bcafa726dd486e90a5341c9e76df27

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Akademický článek

O Projeto Local e sua Investigação de Estratégias de Solução de Problemas como uma Medida de Efeitos Curriculares Longitudinais sobre a Aprendizagem dos Alunos

Autor: Jinfa Cai, Steven Silber, Stephen Hwang, Bikai Nie, John C. Moyer, Ning Wang

Publikováno v: REMATEC. Revista de Matemática, Ensino e Cultura, Vol 11, Iss 21 (2016)

Este artigo apresenta um resumo de importantes resultados relativos aos Anos Finais do Ensino Fundamental, obtidos a partir do projeto LieCal (Longitudinal Investigation of the Effect of Curriculum on Algebra Learning19) e examina, detalhadamente, os

Externí odkaz: https://doaj.org/article/e11177d008274ebcb9e941ae18133971

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Rapid Entry into Masters in Computing Program for Non-Majors

Autor: John C. Moyer, Gary S. Krenz, Thomas Kaczmarek

Publikováno v: ITiCSE

The COSMIC: Change Opportunity - Start Masters in Computing graduate curriculum initiative strives to provide a rapid entry pathway to a professional Master of Science (MS) degree for individuals who do not have an undergraduate degree in computing,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cd0bafadfb5875328beac5b575c81809
https://doi.org/10.1145/3430665.3456365

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Translational evaluation of novel selective orexin-1 receptor antagonist JNJ-61393215 in an experimental model for panic in rodents and humans

Publikováno v: Translational Psychiatry
Translational Psychiatry, Vol 10, Iss 1, Pp 1-10 (2020)
Translational Psychiatry, 10(1). NATURE PUBLISHING GROUP
Translational Psychiatry, 10(1):308. Nature Publishing Group

Orexin neurons originating in the perifornical and lateral hypothalamic area project to anxiety- and panic-associated neural circuitry, and are highly reactive to anxiogenic stimuli. Preclinical evidence suggests that the orexin system, and particula

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b397cd405d1b36d3e9fc6b0fedee7f63
https://hdl.handle.net/1887/3184546

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Bioavailability and Pharmacokinetics of TRPV1 Antagonist Mavatrep (JNJ-39439335) Tablet and Capsule Formulations in Healthy Men: Two Open-Label, Crossover, Single-Dose Phase 1 Studies

Autor: Joseph Caruso, Prasarn Manitpisitkul, Lucille Russell, Kevin Shalayda, Panna Sanga, John A. Moyer, Bhavna Solanki, Yinka Williams

Publikováno v: Clinical Pharmacology in Drug Development. 7:699-711

To improve room temperature stability and oral bioavailability of mavatrep (JNJ-39439335, a transient receptor potential vanilloid subtype-1 antagonist), various formulations were initially developed and evaluated in 2 phase 1 open-label, randomized,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::191819b167cde1d3331c1c34d950c2dc
https://doi.org/10.1002/cpdd.412

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A multiple-dose double-blind randomized study to evaluate the safety, pharmacokinetics, pharmacodynamics and analgesic efficacy of the TRPV1 antagonist JNJ-39439335 (mavatrep)

Autor: Christopher M. Flores, Arthur J. Mayorga, Gary Romano, John A. Moyer, Kevin Shalayda, Prasarn Manitpisitkul, James S Hutchison, Kanaka Tatikola

Publikováno v: Scandinavian journal of pain. 18(2)

Background and aims: This double-blind (DB), randomized, placebo-controlled, sequential-group, multiple-ascending dose, phase 1 study evaluated safety, pharmacokinetics and pharmacodynamics of JNJ-39439335 in healthy men (part 1), and in participants

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c892c7855d268e467d20d6a0b80309d
https://pubmed.ncbi.nlm.nih.gov/29794306

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