Zobrazeno 1 - 10
of 25
pro vyhledávání: '"John A. Mikszta"'
Autor:
Todd Stewart, Matthew S. Ferriter, Robert G. Ulrich, Vincent J. Sullivan, Jason B. Alarcon, Ajit Joseph M. D'Souza, John A. Mikszta, Joanne Huang, Michelle Evans, Kei Amemiya, Brandi Ford
Publikováno v:
Clinical and Vaccine Immunology. 16:719-725
The potential use of Yersinia pestis as a bioterror agent is a great concern. Development of a stable powder vaccine against Y. pestis and administration of the vaccine by minimally invasive methods could provide an alternative to the traditional liq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53f45f87dd82c8517bcabdfdd611f948
https://doi.org/10.1128/cvi.00447-08
https://doi.org/10.1128/cvi.00447-08
Autor:
Stephane Bonnet, John A. Mikszta, Philippe Emile Fernand Laurent, Paul G. Alchas, Noel G. Harvey, Ronald J. Pettis, Paulina Regolini
Publikováno v:
Vaccine. 25:8833-8842
The advantages of intradermal (ID) vaccine administration have been well documented but difficulties in performing ID vaccination using existing techniques and equipment have limited it's clinical application. In the present study, a new ID injection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::369c8cd76c4f1666785e719b16ad0f11
https://doi.org/10.1016/j.vaccine.2007.10.020
https://doi.org/10.1016/j.vaccine.2007.10.020
Autor:
John M. Brittingham, Joanne Huang, John P. Dekker, Beverly Dyas, John A. Mikszta, Chad J. Roy, Robert G. Ulrich, Vincent J. Sullivan, Cheryl H. Dean, Noel G. Harvey
Publikováno v:
Infection and Immunity. 74:6806-6810
The recombinant protective antigen (rPA) of Bacillus anthracis is a promising anthrax vaccine. We compared serum immunoglobulin G levels and toxin-neutralizing antibody titers in rabbits following delivery of various doses of vaccine by microneedle-b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76b54cafbd66102f2bbfa90d1d3d4442
https://doi.org/10.1128/iai.01210-06
https://doi.org/10.1128/iai.01210-06
Autor:
Matthew S. Ferriter, Juan Huang, C. Robin Hwang, Robert J. Garmise, Vincent J. Sullivan, Anthony J. Hickey, John A. Mikszta, Kevin D. Mar, Timothy M. Crowder
Publikováno v:
AAPS PharmSciTech. 7:E131-E137
The purpose of this research was to prepare a dry powder vaccine formulation containing whole inactivated influenza virus (VIIV) and a mucoadhesive compound suitable for nasal delivery. Powders containing WIIV and either lactose or trehalose were pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8726162b0f0ec263f98cef01e30f720e
https://doi.org/10.1208/pt070119
https://doi.org/10.1208/pt070119
Autor:
Wendy D. Woodley, Matthew S. Ferriter, Duane T. Brandau, Robert G. Ulrich, John A. Mikszta, C. Russell Middaugh, Noel G. Harvey, Ge Jiang, C. Robin Hwang, Kevin D. Mar, Sangeeta B. Joshi, Vincent J. Sullivan, Laura J. Peek, Juan Huang, Brandi Ford
Publikováno v:
Journal of Pharmaceutical Sciences. 95:80-96
Anthrax remainsaseriousthreatworldwideas abioterroragent. Asecond- generationanthraxvaccinecurrentlyunderclinicalevaluationconsistsofarecombinant Protective Antigen (rPA) of Bacillus anthracis. We have previously demonstrated that complete protection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74d2518f49987013860583686671c5a7
https://doi.org/10.1002/jps.20484
https://doi.org/10.1002/jps.20484
Autor:
Cheryl H. Dean, Richard Early, Thomas P. Monath, John A. Mikszta, Andrea M. Waterston, Jason B. Alarcon, Farshad Guirakhoo, Ken Draper
Publikováno v:
Human Vaccines. 1:106-111
Flaviviral diseases such as yellow fever, Japanese encephalitis (JE) and dengue hemorrhagic fever cause enormous morbidity and mortality worldwide. There is an urgent need for alternative technologies for mass vaccination against these and other dise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::685be3ded9b17864ec0d541feedb8932
https://doi.org/10.4161/hv.1.3.1797
https://doi.org/10.4161/hv.1.3.1797
Autor:
Vincent J. Sullivan, C. Robin Hwang, Anthony J. Hickey, Juan Huang, Robert J. Garmise, John A. Mikszta, Kevin D. Mar, Timothy M. Crowder
Publikováno v:
Vaccine. 23:794-801
Intranasal (i.n.) vaccination represents an attractive non-invasive alternative to needle-based injection and provides superior protection at mucosal surfaces. However, new formulations are needed to improve efficacy and reduce the refrigerated stora
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e85eeb12f4c488812e52a40da8bbe33
https://doi.org/10.1016/j.vaccine.2004.06.049
https://doi.org/10.1016/j.vaccine.2004.06.049
Autor:
Ronald J. Pettis, Diane E. Sutter, John A. Mikszta, Jason B. Alarcon, John M. Brittingham, Noel G. Harvey
Publikováno v:
Nature Medicine. 8:415-419
Skin is an attractive target for delivery of genetic therapies and vaccines. However, new approaches are needed to access this tissue more effectively. Here, we describe a new delivery technology based on arrays of structurally precise, micron-scale
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b638030d91e9712ac0e27b1e1dcae810
https://doi.org/10.1038/nm0402-415
https://doi.org/10.1038/nm0402-415
Publikováno v:
The Journal of Immunology. 164:1775-1782
The Ag processing and structural requirements involved in the generation of a major T cell epitope from the hen egg-white lysozyme protein (HEL74–88), containing two cysteine residues at positions 76 and 80, were investigated. Several T cell hybrid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::987ac269c6981cdf7ea008ff9b5db6c6
https://doi.org/10.4049/jimmunol.164.4.1775
https://doi.org/10.4049/jimmunol.164.4.1775
Publikováno v:
The Journal of Immunology. 163:5978-5988
Ag-driven selection mediates effective T cell help and the development of Th cell memory in vivo. To analyze the dynamics of interclonal competition during the selection process in vivo, we use the I-Ek-restricted murine response to pigeon cytochrome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc2dc87ec71529695e9cc785ef0ca49d
https://doi.org/10.4049/jimmunol.163.11.5978
https://doi.org/10.4049/jimmunol.163.11.5978