Distal neuropathic pain in HIV is associated with functional connectivity patterns in default mode and salience networks

Autor: Chelsea C. Hays Weeks, Alan N. Simmons, Irina A. Strigo, Sara Timtim, Ronald J. Ellis, John R. Keltner

Publikováno v: Frontiers in Pain Research, Vol 3 (2022)

HIV-associated distal neuropathic pain (DNP) is one of the most prevalent, disabling, and treatment-resistant complications of HIV, but its biological underpinnings are incompletely understood. While data specific to mechanisms underlying HIV DNP are

Externí odkaz: https://doaj.org/article/8c2b777ed7c349cb82897cb32bc7b152

Evidence for a novel subcortical mechanism for posterior cingulate cortex atrophy in HIV peripheral neuropathy

Autor: Gregory G. Brown, Stephanie Corkran, Earl Umbao, Alan Tong, Eelke Visser, Zachary Calvo, Mark Jenkinson, J. Hampton Atkinson, Alan N. Simmons, Igor Grant, Florin Vaida, Mary Beth Bilder, Sarah L. Archibald, John R Keltner, Ronald J. Ellis, Aleks Sheringov, Colm G. Connolly, Rohit Mande, Donald Franklin, Gagandeep Sahota, Alyssa Dasca

Publikováno v: J Neurovirol

We previously reported that neuropathic pain was associated with smaller posterior cingulate cortical (PCC) volumes, suggesting that a smaller/dysfunctional PCC may contribute to development of pain via impaired mind wandering. A gap in our previous

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::198343f14fe928c1335eee9020fcbdbc
https://doi.org/10.1007/s13365-020-00850-3

Catechol-O-methyltransferase polymorphism Val158Met is associated with distal neuropathic pain in HIV-associated sensory neuropathy

Autor: Jennie Xu, Scott Letendre, Anya Umlauf, Donald Franklin, William S. Bush, Joseph H. Atkinson, John R Keltner, Ronald J. Ellis

Publikováno v: AIDS (London, England), vol 33, iss 10
AIDS

BACKGROUND: Many of those aging with HIV suffer from distal neuropathic pain (DNP) due to HIV-associated sensory neuropathy (HIV-SN). Prior studies have linked chronic pain conditions to a variant of the catechol-O-methyltransferase (COMT), Val(158)M

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::050eec76ad9aaaa29894e2cda3ed9809
https://doi.org/10.1097/qad.0000000000002240

HIV peripheral neuropathy-related degeneration of white matter tracts to sensorimotor cortex

Autor: Sara H. Timtim, Alan N. Simmons, Chelsea Hays, Irina Strigo, Scott Sorg, Ronald Ellis, John R. Keltner

Publikováno v: Journal of neurovirology. 28(4-6)

Human immunodeficiency virus-associated distal sensory polyneuropathy (HIV-DSP) affects up to 50% of people with HIV and is associated with depression, unemployment, and generally worsened quality of life. Previous work on the cortical mechanism of H

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ba5f5040f68a4d2216b0ea733578e3b
https://pubmed.ncbi.nlm.nih.gov/36207560

Chronic Distal Sensory Polyneuropathy Is a Major Contributor to Balance Disturbances in Persons Living With HIV

Autor: John R Keltner, Raeanne C. Moore, Bin Tang, Patrick Delaney, Duaa Z Sakabumi, Ronald J. Ellis

Publikováno v: Sakabumi, Duaa Z; Moore, Raeanne C; Tang, Bin; Delaney, Patrick A; Keltner, John R; & Ellis, Ronald J. (2019). Chronic Distal Sensory Polyneuropathy Is a Major Contributor to Balance Disturbances in Persons Living With HIV.. Journal of acquired immune deficiency syndromes (1999), 80(5), 568-573. doi: 10.1097/qai.0000000000001953. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/7555011z
Journal of acquired immune deficiency syndromes (1999), vol 80, iss 5

Author(s): Sakabumi, Duaa Z; Moore, Raeanne C; Tang, Bin; Delaney, Patrick A; Keltner, John R; Ellis, Ronald J | Abstract: BackgroundMedical comorbidities accumulate in older persons living with HIV (PLWH), causing disability and reduced quality of l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::797235a96a0b3c32c0bf726200cb496e
http://www.escholarship.org/uc/item/7555011z