Zobrazeno 1 - 8
of 8
pro vyhledávání: '"John A. Gaynes"'
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Center-surround receptive fields are typically considered to mediate edge detection. Here, by studying retinal bipolar cells responding to flashed and moving stimuli, the authors reveal an additional function: enhanced representation of newly appeari
Externí odkaz:
https://doaj.org/article/81d98e8e273f4421b05e3c3d97b54bf8
Publikováno v:
eLife, Vol 12 (2023)
The processing of visual information by retinal starburst amacrine cells (SACs) involves transforming excitatory input from bipolar cells (BCs) into directional calcium output. While previous studies have suggested that an asymmetry in the kinetic pr
Externí odkaz:
https://doaj.org/article/59ed1dccf2264e4b98fd7094f42e4b03
Autor:
Xiaodong Li, Patrick J Gordon, John A Gaynes, Alexandra W Fuller, Randy Ringuette, Clayton P Santiago, Valerie Wallace, Seth Blackshaw, Pulin Li, Edward M Levine
Publikováno v:
eLife, Vol 11 (2022)
An important question in organogenesis is how tissue-specific transcription factors interact with signaling pathways. In some cases, transcription factors define the context for how signaling pathways elicit tissue- or cell-specific responses, and in
Externí odkaz:
https://doaj.org/article/ca3b0eea0dd1481fa5ffd8a5fb16ce79
Autor:
Yuanyuan Xie, Dan Kaufmann, Matthew J Moulton, Samin Panahi, John A Gaynes, Harrison N Watters, Dingxi Zhou, Hai-Hui Xue, Camille M Fung, Edward M Levine, Anthea Letsou, K C Brennan, Richard I Dorsky
Publikováno v:
PLoS Biology, Vol 15, Iss 8, p e2002257 (2017)
While innate behaviors are conserved throughout the animal kingdom, it is unknown whether common signaling pathways regulate the development of neuronal populations mediating these behaviors in diverse organisms. Here, we demonstrate that the Wnt/ß-
Externí odkaz:
https://doaj.org/article/614fc274f2bf42909a50097c2b06d9c1
Autor:
Edward M. Levine, Pulin Li, Seth Blackshaw, Valerie A. Wallace, Clayton P. Santiago, Randy Ringuette, Alexandra W. Fuller, John A. Gaynes, Patrick J. Gordon, Xiaodong Li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f13056604675f0cab6fdd88f9dc3d91
https://doi.org/10.15252/rc.2022584400
https://doi.org/10.15252/rc.2022584400
Autor:
John A Gaynes, Hideo Otsuna, Douglas S Campbell, John P Manfredi, Edward M Levine, Chi-Bin Chien
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0134751 (2015)
Attractive growth cone turning requires Igf2bp1-dependent local translation of β-actin mRNA in response to external cues in vitro. While in vivo studies have shown that Igf2bp1 is required for cell migration and axon terminal branching, a requiremen
Externí odkaz:
https://doaj.org/article/700c42b15c8847ec81f0ab4dda195363
Publikováno v:
Nature communications. 13(1)
Antagonistic interactions between center and surround receptive field (RF) components lie at the heart of the computations performed in the visual system. Circularly symmetric center-surround RFs are thought to enhance responses to spatial contrasts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bd862ec7b9daed6e9b1246dc4a08b5b
https://pubmed.ncbi.nlm.nih.gov/36163249
https://pubmed.ncbi.nlm.nih.gov/36163249
How neuronal connections are established during development is one of the most fascinating questions in the field of neurobiology. The zebrafish retinotectal system offers distinct advantages for studying axon guidance in an in vivo context. Its acce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d35aa473a52fc5ee1618af558af37b3
https://doi.org/10.1016/b978-0-12-384892-5.00001-3
https://doi.org/10.1016/b978-0-12-384892-5.00001-3