Zobrazeno 1 - 10
of 203
pro vyhledávání: '"John A. Frost"'
Autor:
Nicole M. Revie, Nicole Robbins, Luke Whitesell, John R. Frost, Solomon D. Appavoo, Andrei K. Yudin, Leah E. Cowen
Publikováno v:
mSphere, Vol 5, Iss 2 (2020)
ABSTRACT Opportunistic pathogens of the genus Candida reign as the leading cause of mycotic disease and are associated with mortality rates greater than 40%, even with antifungal intervention. This is in part due to the limited arsenal of antifungals
Externí odkaz:
https://doaj.org/article/7fcd951d919f45c5a4cff456bb66d52f
Autor:
John W. Frost, Srisha Hebbar
Publikováno v:
Endoscopy International Open, Vol 06, Iss 06, Pp E664-E668 (2018)
Background and study aims Cyanoacrylate glue is recommended first-line endoscopic therapy for gastric fundal varices but it is difficult to use and carries a risk of embolization. Thrombin is preferred by many in the UK, but its effectiveness can be
Externí odkaz:
https://doaj.org/article/16166043a5874fc0922b2361f3f2dc06
Publikováno v:
Endoscopy International Open, Vol 05, Iss 07, Pp E559-E562 (2017)
Background and study aims Findings in the literature are conflicting on whether trainee involvement in endoscopic retrograde cholangiopancreatography (ERCP) procedures is detrimental to cannulation success rates. We addressed this in a prospective st
Externí odkaz:
https://doaj.org/article/dc234eefdb3741e9bff1d3107af350a8
Autor:
Brad Sherborne, Andrea M. Peier, Cesear Corona, Ahmad Sadruddin, David P. Lane, Fernando J. Ferrer-Gago, Kaustav Biswas, Dawn Thean, Arun Chandramohan, Tomi K. Sawyer, Christopher J. Brown, Nicolas Boyer, Lan Ge, Tsz Ying Yuen, Lin Yan, John R. Frost, Hung Yi Kristal Kaan, Scott D. Edmondson, Jeffrey D. Hermes, Anthony W. Partridge, Xue Er Lee, Ruchia Duggal, Chad Zimprich, Matthew B. Robers, Charles W. Johannes
Publikováno v:
ACS chemical biology. 16(2)
Macrocyclic peptides open new opportunities to target intracellular protein-protein interactions (PPIs) that are often considered nondruggable by traditional small molecules. However, engineering sufficient membrane permeability into these molecules
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::607ce9191a77b1a17969c8e5ffca84ec
https://pubmed.ncbi.nlm.nih.gov/33539064
https://pubmed.ncbi.nlm.nih.gov/33539064
Autor:
Timothy J. Trinklein, Malati Thapa, Lexie A. Lanphere, Joseph H. Aldstadt, John A. Frost, Sandra M. Koresch
Publikováno v:
Talanta. 231
Synthetic cathinones are a class of new psychoactive substances (NPS), an emerging group of analogues to traditional illicit drugs which are functionalized to circumvent legal regulations. The analytical investigation of NPS by traditional methods, s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0a1152cfb99d396fcd369719fa72286
https://pubmed.ncbi.nlm.nih.gov/33965022
https://pubmed.ncbi.nlm.nih.gov/33965022
Autor:
Solomon D. Appavoo, Nicole M. Revie, Andrei K. Yudin, Luke Whitesell, Nicole Robbins, John R. Frost, Leah E. Cowen
Publikováno v:
mSphere
mSphere, Vol 5, Iss 2, p e00256-20 (2020)
mSphere, Vol 5, Iss 2 (2020)
mSphere, Vol 5, Iss 2, p e00256-20 (2020)
mSphere, Vol 5, Iss 2 (2020)
Fungal infections, such as those caused by pathogenic Candida species, pose a serious threat to human health. Treating these infections relies heavily on the use of azole antifungals; however, resistance to these drugs develops readily, demanding nov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8097ac1d26803eaf2449efac2e58b62
https://doi.org/10.1128/msphere.00256-20
https://doi.org/10.1128/msphere.00256-20
Autor:
Tao Meng, Nicholas A. Pierson, John R. Frost, Chunhui Huang, Natalya Pissarnitski, Jake Z. Essman
Publikováno v:
Peptide Science. 112
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf066109bd1766e384aa2e5c858b08d7
https://doi.org/10.1002/pep2.24160
https://doi.org/10.1002/pep2.24160
Publikováno v:
Journal of the American Chemical Society. 140:8763-8770
Synthetic methods that provide control over macrocycle conformation represent valuable tools for the discovery of bioactive molecules. Incorporation of heterocycles into cyclic peptides may offer a way to stabilize their solution conformations. Herei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dcb1d0ac02f897746e7778bac1a3b7c
https://doi.org/10.1021/jacs.8b04412
https://doi.org/10.1021/jacs.8b04412
Publikováno v:
Journal of Chemical Education. 95:962-969
Solubility is frequently introduced at the high school and introductory college levels through the symbolic domain using net ionic equations and solubility product constants. Students may become proficient with spectator ion cancellation and skilled
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f4a4e96927eef6af371e21629365287
https://doi.org/10.1021/acs.jchemed.7b00965
https://doi.org/10.1021/acs.jchemed.7b00965
Publikováno v:
Journal of Chemical Education. 94:38-43
Development of benchtop, portable Fourier transform nuclear magnetic resonance (NMR) and infrared (IR) spectrometers has opened up opportunities for creating university–high school partnerships that provide high school students with hands-on experi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60f6e302a39c8192180a48b367fc6d5b
https://doi.org/10.1021/acs.jchemed.6b00406
https://doi.org/10.1021/acs.jchemed.6b00406