Zobrazeno 1 - 10
of 91
pro vyhledávání: '"John A. DeSimone"'
Autor:
Jie Qian, Shobha Mummalaneni, Tam-Hao T Phan, Gerard L Heck, John A DeSimone, David West, Sunila Mahavadi, Deanna Hojati, Karnam S Murthy, Mee-Ra Rhyu, Andrew I Spielman, Mehmet Hakan Özdener, Vijay Lyall
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171335 (2017)
During postnatal development rats demonstrate an age-dependent increase in NaCl chorda tympani (CT) responses and the number of functional apical amiloride-sensitive epithelial Na+ channels (ENaCs) in salt sensing fungiform (FF) taste receptor cells
Externí odkaz:
https://doaj.org/article/ea71b7d7bff144038341cb35f5fe30ed
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0127936 (2015)
Nicotine elicits bitter taste by activating TRPM5-dependent and TRPM5-independent but neuronal nAChR-dependent pathways. The nAChRs represent common targets at which acetylcholine, nicotine and ethanol functionally interact in the central nervous sys
Externí odkaz:
https://doaj.org/article/6b09195c07344805a2bd43fc82bcbd31
Autor:
Shobha Mummalaneni, Jie Qian, Tam-Hao T Phan, Mee-Ra Rhyu, Gerard L Heck, John A DeSimone, Vijay Lyall
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e98049 (2014)
The effects of small molecule ENaC activators N,N,N-trimethyl-2-((4-methyl-2-((4-methyl-1H-indol-3-yl)thio)pentanoyl)oxy)ethanaminium iodide (Compound 1) and N-(2-hydroxyethyl)-4-methyl-2-((4-methyl-1H-indol-3-yl)thio)pentanamide (Compound 2), were t
Externí odkaz:
https://doaj.org/article/32c4f55e43c246a8852849316ba0dab3
Publikováno v:
Chemical Senses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2db54997f2638a677ab57a15fc5e6121
https://doi.org/10.1201/9781003210146-3
https://doi.org/10.1201/9781003210146-3
Autor:
John A. DeSimone, I. Scott Ramsey
Publikováno v:
The Journal of General Physiology
Tight control of intracellular pH (pHi) is fundamental to cellular homeostasis. Liman and colleagues’ discovery of a new family of H+-permeable ion channels conserved from nematodes to insects and man (see [Tu et al.][1]) represents an exciting new
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed09756035bb6d1c7a9c0c02f1487eca
https://doi.org/10.1085/jgp.201812003
https://doi.org/10.1085/jgp.201812003
Autor:
John A. DeSimone
Publikováno v:
Chemical Engineering Science. 168:289-308
The dynamics of the taste neural response are highly dependent on the velocity of the stimulus solution delivered to the taste receptor cells. In anesthetized rats, stimulus solution delivered at high stimulus flow rate (1 m1/s) to the taste receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df1db6b7a329aea26f43f918ca4cf206
https://doi.org/10.1016/j.ces.2017.04.034
https://doi.org/10.1016/j.ces.2017.04.034
Autor:
Sunila Mahavadi, John R. Grider, John A. DeSimone, Vijay Lyall, Norman Hurst, Zachary L. Bradley, John F. Kuemmerle, Derek M. Kendig, Karnam S. Murthy
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 307:G1100-G1107
Intraluminal nutrients in the gut affect the peristaltic reflex, although the mechanism is not well defined. Recent evidence supports the presence of taste receptors and their signaling components in enteroendocrine cells, although their function is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4d8ddb71e11a9406e3b0b7ddc63a773
https://doi.org/10.1152/ajpgi.00251.2014
https://doi.org/10.1152/ajpgi.00251.2014
Publikováno v:
Nutrition Reviews. 71:52-59
This article is based on proceedings from the Symposium on Sodium in the Food Supply: Challenges and Opportunities, sponsored by the North American Branch of the International Life Sciences Institute, at Experimental Biology 2010 in Anaheim, Californ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a030f383c6e8c7db3de923a5c8b49b58
https://doi.org/10.1111/nure.12006
https://doi.org/10.1111/nure.12006
Autor:
Tam-Hao T. Phan, Gerard L. Heck, Vijay Lyall, Shobha Mummalaneni, John A. DeSimone, ZuoJun Ren
Publikováno v:
Journal of Neurophysiology. 108:3206-3220
The relationship between taste receptor cell (TRC) Ca2+ concentration ([Ca2+]i) and rat chorda tympani (CT) nerve responses to salty [NaCl and NaCl+benzamil (Bz)] and sour (HCl, CO2, and acetic acid) taste stimuli was investigated before and after li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1c41d71d9138f9717911a36340bb460
https://doi.org/10.1152/jn.00916.2011
https://doi.org/10.1152/jn.00916.2011
Autor:
Mehmet Hakan Ozdener, Vijay Lyall, Deanna Hojati, Karnam S. Murthy, Gerard L. Heck, David West, Jie Qian, Sunila Mahavadi, Andrew I. Spielman, Shobha Mummalaneni, Mee Ra Rhyu, Tam Hao T. Phan, John A. DeSimone
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 2, p e0171335 (2017)
PLoS ONE, Vol 12, Iss 2, p e0171335 (2017)
During postnatal development rats demonstrate an age-dependent increase in NaCl chorda tympani (CT) responses and the number of functional apical amiloride-sensitive epithelial Na+ channels (ENaCs) in salt sensing fungiform (FF) taste receptor cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::430c6a9a812df557322066eee1974701
https://pubmed.ncbi.nlm.nih.gov/28192441
https://pubmed.ncbi.nlm.nih.gov/28192441