Zobrazeno 1 - 10
of 58
pro vyhledávání: '"John A. Colgan"'
Publikováno v:
Journal of Pediatric Surgery Open, Vol 8, Iss , Pp 100172- (2024)
Background: Podcasts are a popular form of extracurricular education. They provide a range of benefits for listeners including an opportunity for learning whilst mobile. We aimed to assess the interest of medical students in a podcast series as a par
Externí odkaz:
https://doaj.org/article/2642013dfe704661aaf6c96ac59c2234
Autor:
John N. Colgan, Noemi A. Fuentes-Bolanos, Draga Barbaric, Luciano Dalla-Pozza, Richard Mitchell, Sujith Samarasinghe, Martin Schrappe, Katherine M. Tucker, Kjeld Schmiegelow, Toby N. Trahair
Publikováno v:
EJC Paediatric Oncology, Vol 2, Iss , Pp 100133- (2023)
Acquired TP53 alterations are present in > 90% of cases of paediatric low-hypodiploid acute lymphoblastic leukaemia (ALL), and ≈ 50% of patients with this subtype harbor germline pathogenic / likely pathogenic (P/LP) TP53 alterations. Despite dose
Externí odkaz:
https://doaj.org/article/dd2b4c1e55764ed7a00cdb8c01f88221
Autor:
John J Colgan, Michael B Burns
Celiac disease is an autoimmune disorder of the small intestine in which gluten, an energy-storage protein expressed by wheat and other cereals, elicits an immune response leading to villous atrophy. Despite a strong genetic component, the disease ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f35117e6ffccf14cf0ac2393b1182191
https://doi.org/10.1101/2022.10.05.510990
https://doi.org/10.1101/2022.10.05.510990
Autor:
John J Colgan, Michael B Burns
Celiac disease is an autoimmune disorder of the small intestine in which gluten, an energy-storage protein found in wheat and other cereals, elicits an immune response that leads to villous atrophy. Despite a strong genetic component, celiac disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85310b910e3ea54c93d1cad2ab34c982
https://doi.org/10.1101/2022.10.02.510531
https://doi.org/10.1101/2022.10.02.510531
Publikováno v:
Exp Hematol
The Gon4l gene encodes a putative transcriptional regulator implicated in the control of both cell differentiation and proliferation. Previously, we described a mutant mouse strain called Justy in which splicing of pre-mRNA generated from Gon4l is di
Autor:
Thomas J. Waldschmidt, Meiling Jin, Hai-Hui Xue, Qianze Dong, Hasem Habelhah, Youzhong Yuan, Wei Wang, Ji Yuan, Chen Zhao, Nicholas Borcherding, Joseph D. Khoury, Iannis Aifantis, Qingchang Li, Brendan F. Boyce, Andrew L. Feldman, Markus Müschen, Lili Wang, Francesco Boccalatte, Shimin Hu, Benjamin W. Darbro, Endi Wang, Adam Bagg, Lin Fu, Yan Xiu, Aaron D. Bossler, Xiaobing Tang, Mariah R. Leidinger, Jose Luis Sardina, Siegfried Janz, John D. Colgan
Publikováno v:
Blood
NF-κB and Notch signaling can be simultaneously activated in a variety of B-cell lymphomas. Patients with B-cell lymphoma occasionally develop clonally related myeloid tumors with poor prognosis. Whether concurrent activation of both pathways is suf
Publikováno v:
Immunological investigations. 51(6)
The nonreceptor tyrosine kinase ITK is a key component of the T cell receptor (TCR) signaling pathway and is required for cytokine production by CD4+ T cells that have differentiated into Th2 cells. Structural and biochemical studies suggest that con
Autor:
Jacob V. Gorman, John D. Colgan
Publikováno v:
Immunology. 154:418-433
T‐cell immunoglobulin and mucin domain 3 (Tim‐3) is a surface receptor expressed by T helper type 1 (Th1) effector CD4 T cells, which are critical for defence against intracellular pathogens and have been implicated in autoimmune disease. Previou
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23061 (2011)
CD40 is a cell surface receptor important in the activation of antigen-presenting cells during immune responses. In macrophages and dendritic cells, engagement of CD40 by its ligand CD154 provides signals critical for anti-microbial and T cell-mediat
Externí odkaz:
https://doaj.org/article/9391969be9b942818e547b8224c4d263
Autor:
Bruce S Hostager, Daniel K Fox, Douglas Whitten, Curtis G Wilkerson, Betty A Eipper, Victor P Francone, Paul B Rothman, John D Colgan
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e11380 (2010)
The tumor necrosis factor receptor (TNFR) superfamily mediates signals critical for regulation of the immune system. One family member, CD40, is important for the efficient activation of antibody-producing B cells and other antigen-presenting cells.
Externí odkaz:
https://doaj.org/article/86d4cc668d754adb959614d8440bd1e6