Zobrazeno 1 - 8
of 8
pro vyhledávání: '"John A. Cavins"'
Autor:
Faye C. Austin, Edmund Klein, Isaac Djerassi, John A. Cavins, David L. Levin, Robert W. Case, Dutzu Rosner, Charles W. Boone
Publikováno v:
Cancer. 49:2034-2042
Crude membrane (CM) extracts were prepared from five cultured breast tumor lines (MDA-MB-157, MDA-MB-231, ZR75-1, HS0578T, and MCF-7) which had been infected with vesicular stomatitis virus (VSV) to augment their antigenicity. In skin test trials, CM
Publikováno v:
Cryobiology. 5:60-69
Summary The low temperature preservation of leukocytes has been emphasized recently owing to its inherent application in the treatment of leukopenic individuals. Ten per cent dimethyl sulfoxide has evolved as the additive of choice for this cell syst
Autor:
John A. Cavins
Publikováno v:
Journal of Surgical Oncology. 3:325-329
A 3-year experience with topical chemo- and immunotherapy of superficial cutaneous neoplasms is reviewed. Agents used were 5-fluorouracil (5-FU), Trenimon (TEIB), and dinitrochlorobenzene (DNCB). The antitumor effect of FU is a result of direct cytos
Autor:
Robert L. Wall, John A. Cavins
Publikováno v:
The American Journal of Medicine. 29:444-448
Fourteen patients with PTA deficiency are reviewed, including a family with six bleeders in the past two generations. Data are presented which show that the bleeding tendency in this disorder is often mild, as hitherto emphasized, but may also be of
Autor:
Thomas C. Hall, Christiaan L. Khung, C. Thomas Griffiths, William J. Yount, John A. Cavins, Margarida M. Dederick
Publikováno v:
Cancer. 19:1008-1012
Eighty-seven patients with histologically proven cancer were given a course of 5-fluorouracil to study the effect of time of infusion and of 5% glucose in regard to toxicity and antitumor effectiveness. The over-all response rate of 25% was unrelated
Publikováno v:
Cryobiology. 4:209-211
Summary Human leukocytes were slowly frozen in media containing 25% serum and 10% dimethyl sulfoxide. After thawing and resuspending, differences in cellular permeability to several compounds were found, and concentrative transport of cycloleucine co
Publikováno v:
Cryobiology. 2(3)
Summary Leukocytes were sedimented from buffy coats. Dimethyl sulfoxide (DMSO) was added to make final conceutrations of 10% and 15%. Aliquots were frozen in a Linde graded temperature apparatus to −195°C at a rate of 1°C per min in the critical
Publikováno v:
Transfusion. 6(6)
Human platelets preserved by freezing to –196 C in plasma containing 5% dextrose and 5% dimethylsulfoxide were administered to 35 thrombocytopenic patients with acute leukemia or aplastic anemia on 70 occasions. The platelet counts of the recipient