AFAP1 Is a Novel Downstream Mediator of TGF-β1 for CCN2 Induction in Osteoblasts.

Autor: Youngjin Cho, Rachel Silverstein, Max T Geisinger, Stephen Martinkovich, Holly Corkill, Jess M Cunnick, Sonia L Planey, John A Arnott

Publikováno v: PLoS ONE, Vol 10, Iss 9, p e0136712 (2015)

BACKGROUND:CCN2 acts as an anabolic growth factor to regulate osteoblast differentiation and function. CCN2 is induced by TGF-β1 and acts as a mediator of TGF-β1 induced matrix production in osteoblasts and Src is required for CCN2 induction by TGF

Externí odkaz: https://doaj.org/article/fd464c067d9a4f29934c735c08e60ef8

Contributors

Autor: Marah Armouti, John A. Arnott, Kushal Bakshi, Natalie J. Bales, Mary Beth Bauer, Nathan A. Berger, Daniel J. Bernard, Mark Blostein, M. Luisa Bonet, Amanda P. Borrow, Gregory A. Brent, Emilie Brûlé, Max H. Cake, Giulia Cantini, Ayano Chiba, George P. Chrousos, Sila Cocciolillo, R. Comaposada-Baró, Kevin P.M. Currie, Pierre De Meyts, Ilaria Dicembrini, Clark W. Distelhorst, Nikoletta Dobos, David E. Fisher, M.L. Franco, Gabor Halmos, Robert J. Handa, Elie Hobeika, Eva Juhasz, Hamsini Sudheer Kala, Lajos V. Kemeny, Ruth A. Keri, Haruka Kobayashi, Christopher S. Kovacs, Kalman Kovacs, Pierre J. Lefèbvre, Carole Le Henaff, P.R. Le Tissier, Gerald Litwack, Yan-Yun Liu, null Sonia Lobo, Michaela Luconi, David J. Lyons, Rong Ma, Robert T. Mallet, Edoardo Mannucci, Anna Milanesi, Naoki Mochizuki, J.F. Murray, Nicolas C. Nicolaides, Kostas Pantopoulos, Nicola C. Partridge, Doodipala Samba Reddy, Lina M. Restrepo, Joan Ribot, Allison J. Richard, Ana M. Rodríguez, Nicola Romanò, Fabio Rotondo, Andrew V. Schally, Giada Sebastiani, Carlos A. Serna, Nima Sharifi, null Michael J. Shipston, Jacqueline M. Stephens, Carlos Stocco, Sally A. Stover, Luis V. Syro, Zsuzsanna Szabo, Martina Trabucco, M. Vilar, David E. Volk, Helge Waldum, Richard J. Wurtman, George C.T. Yeoh, Yue Yu, Eleonora Zakharian

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dbafbe5d4c7728d21ffa288fc9c5aa51
https://doi.org/10.1016/b978-0-12-813814-4.01002-6

Ets-1 is essential for connective tissue growth factor (CTGF/CCN2) induction by TGF-β1 in osteoblasts.

Autor: Max T Geisinger, Randy Astaiza, Tiffany Butler, Steven N Popoff, Sonia Lobo Planey, John A Arnott

Publikováno v: PLoS ONE, Vol 7, Iss 4, p e35258 (2012)

Ets-1 controls osteoblast differentiation and bone development; however, its downstream mechanism of action in osteoblasts remains largely undetermined. CCN2 acts as an anabolic growth factor to regulate osteoblast differentiation and function. CCN2

Externí odkaz: https://doaj.org/article/183748685a024721b92cf0203672b33c

Involving People with Cognitive and Communication Impairments in Mobile Health App Design

Autor: Robyn McNaughton, Matthew Malone, John L. Arnott, Susan D Munro, Bernadette Brophy-Arnott, Gareth Lloyd

Publikováno v: ASSETS

Multiple challenges face people with cognitive and communication impairments when asked to be involved in the design of technology that is appropriate for them. This population is under-represented in healthcare research and have health inequalities

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a887d3e35177f484c910323db540958e
https://doi.org/10.1145/3234695.3240998

Mobile Delivery of Health Information for People with Mild Cognitive Impairment

Autor: Gareth, Lloyd, Susan D, Munro, John L, Arnott

Publikováno v: Studies in health technology and informatics. 242

The design of a smartphone application (app) for promoting healthy lifestyle choices has been investigated for people with mild cognitive impairment. The app was designed to provide health-related messages and assist users to keep track of activities

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8dabb3546c96566f0a164b73bf9112b5
https://pubmed.ncbi.nlm.nih.gov/28873773