Population Structure and Antimicrobial Resistance in Campylobacter jejuni and C. coli Isolated from Humans with Diarrhea and from Poultry, East Africa

Autor: Nigel P. French, Kate M. Thomas, Nelson B. Amani, Jackie Benschop, Godfrey M. Bigogo, Sarah Cleaveland, Ahmed Fayaz, Ephrasia A. Hugho, Esron D. Karimuribo, Elizabeth Kasagama, Ruth Maganga, Matayo L. Melubo, Anne C. Midwinter, Blandina T. Mmbaga, Victor V. Mosha, Fadhili I. Mshana, Peninah Munyua, John B. Ochieng, Lynn Rogers, Emmanuel Sindiyo, Emanuel S. Swai, Jennifer R. Verani, Marc-Alain Widdowson, David A. Wilkinson, Rudovick R. Kazwala, John A. Crump, Ruth N. Zadoks

Publikováno v: Emerging Infectious Diseases, Vol 30, Iss 10, Pp 2079-2089 (2024)

Campylobacteriosis and antimicrobial resistance (AMR) are global public health concerns. Africa is estimated to have the world’s highest incidence of campylobacteriosis and a relatively high prevalence of AMR in Campylobacter spp. from humans and a

Externí odkaz: https://doaj.org/article/469e28b1578f42e48ef3af63e8ebc66e

Predicting mortality in febrile adults: comparative performance of the MEWS, qSOFA, and UVA scores using prospectively collected data among patients in four health-care sites in sub-Saharan Africa and South-Eastern AsiaResearch in context

Autor: Sham Lal, Manophab Luangraj, Suzanne H. Keddie, Elizabeth A. Ashley, Oliver Baerenbold, Quique Bassat, John Bradley, John A. Crump, Nicholas A. Feasey, Edward W. Green, Kevin C. Kain, Ioana D. Olaru, David G. Lalloo, Chrissy h. Roberts, David C.W. Mabey, Christopher C. Moore, Heidi Hopkins, Sara Ajanovic, Benjamin Amos, Stéphanie Baghoumina, Núria Balanza, Tsitsi Bandason, Tapan Bhattacharyya, Stuart D. Blacksell, Zumilda Boca, Christian Bottomley, Justina M. Bramugy, Clare IR. Chandler, Vilada Chansamouth, Mabvuto Chimenya, Joseph Chipanga, Anelsio Cossa, Ethel Dauya, Catherine Davis, Xavier de Lamballerie, Justin Dixon, Somyoth Douangphachanh, Audrey Dubot-Pérès, Michelle M. Durkin, Rashida A. Ferrand, Colin Fink, Elizabeth JA. Fitchett, Alessandro Gerada, Stephen R. Graves, Edward Green, Becca L. Handley, Coll D. Hutchison, Risara Jaksuwan, Jessica Jervis, Jayne Jones, Khamxeng Khounpaseuth, Katharina Kranzer, Khamfong Kunlaya, Pankaj Lal, Yoel Lubell, David CW. Mabey, Eleanor MacPherson, Forget Makoga, Sengchanh Manichan, Tegwen Marlais, Florian Maurer, Mayfong Mayxay, Michael Miles, Polycarp Mogeni, Campos Mucasse, Paul N. Newton, Chelsea Nguyen, Vilayouth Phimolsarnnousith, Mathieu Picardeau, Chrissy H. Roberts, Amphone Sengduangphachanh, Siho Sengsavang, Molly Sibanda, Somvai Singha, John Stenos, Ampai Tanganuchitcharnchai, Hira Tanvir, James E. Ussher, Marta Valente, Marie A. Voice, Manivanh Vongsouvath, Msopole Wamaka, L Joseph Wheat, Shunmay Yeung

Publikováno v: EClinicalMedicine, Vol 77, Iss , Pp 102856- (2024)

Summary: Background: Clinical severity scores can identify patients at risk of severe disease and death, and improve patient management. The modified early warning score (MEWS), the quick Sequential (Sepsis-Related) Organ Failure Assessment (qSOFA),

Externí odkaz: https://doaj.org/article/472ab60c07af4c819f058bc83c88007e

Molecular and clinical epidemiology of carbapenem resistant Acinetobacter baumannii, Pseudomonas aeruginosa and Enterobacterales in Fiji: a multicentre prospective observational studyResearch in context

Autor: Sakiusa C. Baleivanualala, Silivia Matanitobua, Vika Soqo, Shayal Smita, Josese Limaono, Sajnel C. Sharma, Swastika V. Devi, Lusiana V. Boseiwaqa, Numa Vera, Silpa Kumar, Amele Lalibuli, Josese Mailulu, Donald Wilson, Yvette Samisoni, John A. Crump, James E. Ussher

Publikováno v: The Lancet Regional Health. Western Pacific, Vol 47, Iss , Pp 101095- (2024)

Summary: Background: Carbapenem resistant organisms (CROs) such as Acinetobacter baumannii (CRAb), Pseudomonas aeruginosa (CRPa), Escherichia coli (CREc), and Klebsiella pneumoniae (CRKp) have been identified by the World Health Organization (WHO) as

Externí odkaz: https://doaj.org/article/5b74e89a77a1420d875672cbbb91114f

Host-response transcriptional biomarkers accurately discriminate bacterial and viral infections of global relevance

Autor: Emily R. Ko, Megan E. Reller, L. Gayani Tillekeratne, Champica K. Bodinayake, Cameron Miller, Thomas W. Burke, Ricardo Henao, Micah T. McClain, Sunil Suchindran, Bradly Nicholson, Adam Blatt, Elizabeth Petzold, Ephraim L. Tsalik, Ajith Nagahawatte, Vasantha Devasiri, Matthew P. Rubach, Venance P. Maro, Bingileki F. Lwezaula, Wasantha Kodikara-Arachichi, Ruvini Kurukulasooriya, Aruna D. De Silva, Danielle V. Clark, Kevin L. Schully, Deng Madut, J. Stephen Dumler, Cecilia Kato, Renee Galloway, John A. Crump, Geoffrey S. Ginsburg, Timothy D. Minogue, Christopher W. Woods

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)

Abstract Diagnostic limitations challenge management of clinically indistinguishable acute infectious illness globally. Gene expression classification models show great promise distinguishing causes of fever. We generated transcriptional data for a 2

Externí odkaz: https://doaj.org/article/6b810e23001a49d88802db46e9e5c9d3

Mapping the incidence rate of typhoid fever in sub-Saharan Africa.

Autor: Jong-Hoon Kim, Jungsoon Choi, Chaelin Kim, Gi Deok Pak, Prerana Parajulee, Andrea Haselbeck, Se Eun Park, Vittal Mogasale, Hyon Jin Jeon, Annie J Browne, Ellis Owusu-Dabo, Raphaël Rakotozandrindrainy, Abdramane Soura Bassiahi, Mekonnen Teferi, Octavie Lunguya-Metila, Christiane Dolecek, Virginia E Pitzer, John A Crump, Simon I Hay, Florian Marks

Publikováno v: PLoS Neglected Tropical Diseases, Vol 18, Iss 2, p e0011902 (2024)

BackgroundWith more than 1.2 million illnesses and 29,000 deaths in sub-Saharan Africa in 2017, typhoid fever continues to be a major public health problem. Effective control of the disease would benefit from an understanding of the subnational geosp

Externí odkaz: https://doaj.org/article/ae21d73cad134d81aa11d8d07bf7cbcb