Zobrazeno 1 - 10
of 5 553
pro vyhledávání: '"John A Thompson"'
Autor:
Franck Carbonnel, Anusha Shirwaikar Thomas, Julie R Brahmer, John A Thompson, Yinghong Wang, Hao Chi Zhang, Bret Lashner, Michel Obeid, Stephen B Hanauer, Malek Shatila, Antonio Pizuorno Machado, Sidra Naz, Nitish Mittal, Christine Catinis, Krishnavathana Varatharajalu, Carolina Colli Cruz, Eric Lu, Deanna Wu, Bryan Schneider, David P Farris
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 11 (2024)
Gastrointestinal immune-related adverse events (GI irAEs) are common manifestations of immune checkpoint inhibitor (ICI) toxicity. We present a comprehensive systematic review of the incidence, management, and clinical course of irAEs across the enti
Externí odkaz:
https://doaj.org/article/f5eba1d7d1a949bcaf4019ce1376b9b5
Autor:
Kevin Conlon, Robert Wesolowski, Douglas G McNeel, John A Thompson, Rom Leidner, Andrea Wang-Gillam, Sumati Gupta, Nancy Lewis, George N Pavlakis, Lang Ho Lee, Monica Chaudhari, Nadia Hassounah, Jong Bong Lee, Jessica A O’Keeffe
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 10 (2023)
Background Preclinically, interleukin-15 (IL-15) monotherapy promotes antitumor immune responses, which are enhanced when IL-15 is used in combination with immune checkpoint inhibitors (ICIs). This first-in-human study investigated NIZ985, a recombin
Externí odkaz:
https://doaj.org/article/2886323ab834455e8737872e76203efc
Autor:
Wei Qiao, John A Thompson, Hamzah Abu-Sbeih, Yinghong Wang, Michael Dougan, Mehmet Altan, Michael A Postow, Yousef R Badran, Fangwen Zou, Anusha S Thomas, Sienna M Durbin, Barbara E Dutra, Donna E Leet, Po-Ying Lai, Nora K Horick, David M Faleck
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 6 (2023)
Purpose Immune checkpoint inhibitor (ICI) therapy is often suspended because of immune-related enterocolitis (irEC). We examined the effect of resumption of ICIs with or without concurrent selective immunosuppressive therapy (SIT) on rates of symptom
Externí odkaz:
https://doaj.org/article/68c7351fed9c487bae41ff9ca5853270
Autor:
Thomas F Gajewski, John A Thompson, Sanjay Goel, Brendan D Curti, Elisabeth I Heath, Olivier Rixe, David C Smith, Celine Jacquemont, Tycel Phillips, Martin Gutierrez, Sahar Ansari, Andrew L Coveler, Svetomir N Markovic, Timothy M Kuzel, Amitkumar N Mehta, David L Bajor, Hun Ju Lee, Ajay K Gopal, Paolo Caimi, Ariel Topletz-Erickson, Peigen Zhou, Michael W Schmitt, Juneko E Grilley-Olson
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 6 (2023)
Background SEA-CD40 is an investigational, non-fucosylated, humanized monoclonal IgG1 antibody that activates CD40, an immune-activating tumor necrosis factor receptor superfamily member. SEA-CD40 exhibits enhanced binding to activating FcγRIIIa, po
Externí odkaz:
https://doaj.org/article/997d45d0420040f2a6abbe4400763c7d
Autor:
Danielle McDermott, Marielle L Darwin, Kirsten Fetrow, Ian Coulter, Kristal Biesecker, John A Thompson
Publikováno v:
PLoS ONE, Vol 18, Iss 1, p e0281040 (2023)
This study sought to identify differences in cannabis use and perceptions about cannabis in mitigating seizure-related symptoms in patients with epilepsy, and to evaluate differences in these patterns between drug-resistant versus pharmacoresponsive
Externí odkaz:
https://doaj.org/article/856d1e0dbcf04a4780a5b97678fd24f0
Autor:
Toshihiko Doi, John A Thompson, Omid Hamid, Adi Diab, Siwen Hu-Lieskovan, Jeffrey Chou, Jeffrey S Wasser, Patrick A Ott, Jean-Philippe Spano, Willeke Ros, Alison Forgie, Wenjing Yang, Ferry A L M Eskens, Alberto A Chiappori, Eric Angevin, Naiyer A Rizvi, Cen Guo, Anthony B El-Khoueiry
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 10 (2022)
Background Ivuxolimab (PF-04518600) and utomilumab (PF-05082566) are humanized agonistic IgG2 monoclonal antibodies against OX40 and 4-1BB, respectively. This first-in-human, multicenter, open-label, phase I, dose-escalation/dose-expansion study expl
Externí odkaz:
https://doaj.org/article/ccd14bbe12da44b9bec3de265e3da2d8
Autor:
Sunderland Baker, Anand Tekriwal, Gidon Felsen, Elijah Christensen, Lisa Hirt, Steven G Ojemann, Daniel R Kramer, Drew S Kern, John A Thompson
Publikováno v:
PLoS ONE, Vol 17, Iss 10, p e0275490 (2022)
Optimal placement of deep brain stimulation (DBS) therapy for treating movement disorders routinely relies on intraoperative motor testing for target determination. However, in current practice, motor testing relies on subjective interpretation and c
Externí odkaz:
https://doaj.org/article/0f940a79113b438b85c7775250c6f80e
Autor:
Kevin Conlon, Douglas G McNeel, John A Thompson, Sema Kurtulus, Rom Leidner, Thomas A Waldmann, Andrea Wang-Gillam, William D Figg, Sumati Gupta, Cristina Bergamaschi, George N Pavlakis, Antonio Valentin, Barbara K Felber, Mario Roederer, Dionysios C Watson, Cody J Peer, E Lake Potter, Nehal S Parikh, Debby Long, Lang Ho Lee, Niladri Roy Chowdhury, Florent Bender
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 11 (2021)
Externí odkaz:
https://doaj.org/article/05cda4cb9225447c85e4cdf802228026
Autor:
Jennifer Wang, John A Thompson, Yinghong Wang, Hao Chi Zhang, Fangwen Zou, Jennifer L McQuade, Anusha S Thomas, Isabella C Glitza Oliva
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 1 (2021)
Background Immune-mediated diarrhea and colitis (IMDC) is currently diagnosed and monitored by evaluating clinical symptoms. Deep remission is determined by endoscopic and histologic evaluation of the disease process. However, repeating these invasiv
Externí odkaz:
https://doaj.org/article/8098b76aaf244117b450ebfe45956e91
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0225323 (2019)
Gliomas account for 26.5% of all primary central nervous system tumors. Recent studies have used diffusion tensor imaging (DTI) to extract white matter fibers and the diffusion coefficients derived from MR processing to provide useful, non-invasive i
Externí odkaz:
https://doaj.org/article/5e7ba112bff64914a15eda101e915782