Výsledky vyhledávání - "John A Pollock"

Akademický článek

Imaging neuroinflammation in vivo in a neuropathic pain rat model with near-infrared fluorescence and ¹⁹F magnetic resonance.

Autor: Kiran Vasudeva, Karl Andersen, Bree Zeyzus-Johns, T Kevin Hitchens, Sravan Kumar Patel, Anthony Balducci, Jelena M Janjic, John A Pollock

Publikováno v: PLoS ONE, Vol 9, Iss 2, p e90589 (2014)

Chronic neuropathic pain following surgery represents a serious worldwide health problem leading to life-long treatment and the possibility of significant disability. In this study, neuropathic pain was modeled using the chronic constriction injury (

Externí odkaz: https://doaj.org/article/e15a1956cef5411b9cd1acabc34e64f8

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Akademický článek

Cyclooxgenase-2 inhibiting perfluoropoly (ethylene glycol) ether theranostic nanoemulsions-in vitro study.

Autor: Sravan Kumar Patel, Yang Zhang, John A Pollock, Jelena M Janjic

Publikováno v: PLoS ONE, Vol 8, Iss 2, p e55802 (2013)

Cylcooxgenase-2 (COX-2) expressing macrophages, constituting a major portion of tumor mass, are involved in several pro-tumorigenic mechanisms. In addition, macrophages are actively recruited by the tumor and represent a viable target for anticancer

Externí odkaz: https://doaj.org/article/01e9b9669f3a4a45b94d1e1d55600fb1

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Akademický článek

Folate-conjugated near-infrared fluorescent perfluorocarbon nanoemulsions as theranostics for activated macrophage COX-2 inhibition

Autor: Riddhi Vichare, Caitlin Crelli, Lu Liu, Rebecca McCallin, Abree Cowan, Stefan Stratimirovic, Michele Herneisey, John A. Pollock, Jelena M. Janjic

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-17 (2023)

Abstract Activated macrophages play a critical role in the orchestration of inflammation and inflammatory pain in several chronic diseases. We present here the first perfluorocarbon nanoemulsion (PFC NE) that is designed to preferentially target acti

Externí odkaz: https://doaj.org/article/5c9ee47f32e24f90a81350613e33d5c9

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Akademický článek

Nanomedicine-driven neuropathic pain relief in a rat model is associated with macrophage polarity and mast cell activation

Autor: Muzamil Saleem, Brooke Deal, Emily Nehl, Jelena M. Janjic, John A. Pollock

Publikováno v: Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-21 (2019)

Abstract We explored the immune neuropathology underlying multi-day relief from neuropathic pain in a rat model initiated at the sciatic nerve, by using a nanoemulsion-based nanomedicine as a biological probe. The nanomedicine is theranostic: both th

Externí odkaz: https://doaj.org/article/1a6b0b914a1c4633b57a588492f36e25

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Akademický článek

How media empower the vulnerable: Using community structure theory to analyze relationships between demographics and health reporting

Autor: John C. Pollock

Publikováno v: International Journal of Nursing Sciences, Vol 7, Iss , Pp S16-S18 (2020)

Instead of studying the impact of media on society, the traditional “top down” orientation of most communication studies scholars, this keynote presentation adopted the opposite perspective, exploring the “bottom-up” impact of “society” o

Externí odkaz: https://doaj.org/article/76b77a8726664b77ac4dbf581915af6c

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RNA-Seq Reveals Sex Differences in Gene Expression during Peripheral Neuropathic Inflammation and in Pain Relief from a COX-2 Inhibiting Theranostic Nanoemulsion

Autor: Brooke Deal, Katherine Phillips, Caitlin Crelli, Jelena M. Janjic, John A. Pollock

Publikováno v: International Journal of Molecular Sciences; Volume 24; Issue 11; Pages: 9163

Given decades of neuroinflammatory pain research focused only on males, there is an urgent need to better understand neuroinflammatory pain in females. This, paired with the fact that currently there is no long-term effective treatment for neuropathi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::560320962d495935144c13c49f3cb858
https://doi.org/10.3390/ijms24119163

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US Nationwide Coronavirus Newspaper Coverage of Federal/National Government Responses: Community Structure Theory and a 'Violated Buffer'

Autor: John C. Pollock, Suchir Govindarajan, Alexis Marta, James N. Sparano

Publikováno v: Tripodos. 1:27-48

Community structure analysis (Pollock, 2007, 2013a, 2015) compared city characteristics and newspaper coverage of federal/Trump administration coronavirus responses in 18 major US cities, sampling all 250+ word articles from 01/28/20 to 04/03/20. T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4c03bb21b2d328f616143257b04b403f
https://doi.org/10.51698/tripodos.2020.47p27-48

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Behavioral and inflammatory sex differences revealed by celecoxib nanotherapeutic treatment of peripheral neuroinflammation

Autor: Brooke, Deal, Laura M, Reynolds, Charles, Patterson, Jelena M, Janjic, John A, Pollock

Publikováno v: Scientific Reports. 12

Neuropathic pain affects millions of people worldwide, yet the molecular mechanisms of how it develops and persists are poorly understood. Given that males have historically been utilized as the primary sex in preclinical studies, less is known about

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8035f3593d49afc76e6105ca534f3ea
https://doi.org/10.1038/s41598-022-12248-8

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