Zobrazeno 1 - 10 of 16 pro vyhledávání: '"John A Ellerton"'
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Akademický článek
Avelumab as second-line therapy for metastatic, platinum-treated urothelial carcinoma in the phase Ib JAVELIN Solid Tumor study: 2-year updated efficacy and safety analysis
Autor: James L Gulley, Manish R Patel, Keun-Wook Lee, Luc Dirix, Mary Ruisi, Jeffrey R Infante, Patrick Schöffski, Alain Ravaud, Ding Wang, Andrea B Apolo, John A Ellerton, Manish Agrawal, Michael S Gordon, Raid Aljumaily, Theodore Gourdin, Matthew H Taylor, Juliane Manitz, Gregory Pennock
Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Anti-programmed cell death ligand 1 (PD-L1)/programmed cell death 1 antibodies have shown clinical activity in platinum-treated metastatic urothelial carcinoma, resulting in regulatory approval of several agents, including avelumab (anti-P
Externí odkaz: https://doaj.org/article/8cbddaa59a7041aa874038d1754428b8
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4
Avelumab as second-line therapy for metastatic, platinum-treated urothelial carcinoma in the phase Ib JAVELIN Solid Tumor study: 2-year updated efficacy and safety analysis
Autor: Jeffrey R. Infante, Patrick Schöffski, Michael S. Gordon, Alain Ravaud, Manish Agrawal, John Allan Ellerton, Juliane Manitz, Manish R. Patel, Mary Ruisi, Andrea B. Apolo, Matthew H. Taylor, Luc Dirix, Ding Wang, Keun Wook Lee, Raid Aljumaily, Gregory Pennock, Theodore Gourdin, J.L. Gulley
Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Journal for Immunotherapy of Cancer
BackgroundAnti-programmed cell death ligand 1 (PD-L1)/programmed cell death 1 antibodies have shown clinical activity in platinum-treated metastatic urothelial carcinoma, resulting in regulatory approval of several agents, including avelumab (anti-PD
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b5b9fa96546aac04d870e76ec58182c
https://jitc.bmj.com/content/8/2/e001246.full
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5
Avelumab in metastatic urothelial carcinoma after platinum failure (JAVELIN Solid Tumor): pooled results from two expansion cohorts of an open-label, phase 1 trial
Autor: Galit Rosen, Andrea B. Apolo, Manish R. Patel, Mathew Taylor, Junyuan Xiong, Michael Gordon, Keun Wook Lee, Manish Agrawal, James L. Gulley, Carolyn D. Britten, Ding Wang, Jeffrey R. Infante, John Allan Ellerton, Alain Ravaud, Luc Dirix, Patrick Schöffski, Raid Aljumaily, Arnold B. Gelb
Publikováno v: Lancet Oncol
Translational Cancer Research
Summary Background The approval of anti-programmed death ligand 1 (PD-L1) and anti-programmed death 1 agents has expanded treatment options for patients with locally advanced or metastatic urothelial carcinoma. Avelumab, a human monoclonal anti-PD-L1
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b17458409e554d7d7e53d1e16ee0c45
https://europepmc.org/articles/PMC7984727/
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6
Avelumab treatment in metastatic urothelial carcinoma: Post-hoc analysis of high-risk populations in the phase Ib JAVELIN Solid Tumor Study
Autor: Manish R. Patel, Vijay Kasturi, James L. Gulley, Andrea B. Apolo, John Warth, John Allan Ellerton, Juliane Manitz, Luc Dirix, Galit Rosen
Publikováno v: Journal of Clinical Oncology. 37:428-428
428 Background: Avelumab is a human anti‒PD-L1 IgG1 antibody approved in the US, Canada, and Israel for the treatment of locally advanced or metastatic urothelial carcinoma (mUC) progressed after platinum chemotherapy. In the JAVELIN Solid Tumor st
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::51ab6cd99326284422de4aa94879586b
https://doi.org/10.1200/jco.2019.37.7_suppl.428
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Phase I/II Study of Inhaled Doxorubicin Combined with Platinum-Based Therapy for Advanced Non–Small Cell Lung Cancer
Autor: John R. Murren, William J. Hicks, Gregory A. Otterson, Miguel A. Villalona-Calero, Scott N. Gettinger, John A. Ellerton, Xueliang Pan
Publikováno v: Clinical Cancer Research. 16:2466-2473
Purpose: We have shown the feasibility of administering inhaled doxorubicin to patients with cancer. This study evaluated inhaled doxorubicin combined with cisplatin and docetaxel in patients with non–small cell lung cancer. The principal objective
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5383d884da0043e6039d943c57f62ac
https://doi.org/10.1158/1078-0432.ccr-09-3015
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9
Updated efficacy and safety of avelumab in metastatic urothelial carcinoma (mUC): Pooled analysis from 2 cohorts of the phase 1b Javelin solid tumor study
Autor: Arnold B. Gelb, Alain Ravaud, Patrick Schöffski, Ding Wang, Matthew H. Taylor, Raid Aljumaily, Jeffrey R. Infante, Galit Rosen, Luc Dirix, Andrea B. Apolo, Junyuan Xiong, John Allan Ellerton, Michael S. Gordon, Keun-Wook Lee, Manish R. Patel, Carolyn D. Britten, Manish Agrawal
Publikováno v: Journal of Clinical Oncology. 35:4528-4528
4528 Background: Avelumab, a fully human anti‒PD-L1 IgG1 antibody, has shown promising efficacy and safety in 2 cohorts of patients (pts) with mUC. We now report updated data from a pooled analysis of these pts with mUC from JAVELIN Solid Tumor (NC
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ef5ffc77032a02e26fef3080d7e0a812
https://doi.org/10.1200/jco.2017.35.15_suppl.4528
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Avelumab in patients with metastatic urothelial carcinoma: Pooled results from two cohorts of the phase 1b JAVELIN Solid Tumor trial
Autor: Keun-Wook Lee, Michael S. Gordon, Jeffrey R. Infante, Junyuan Xiong, Alain Ravaud, Arnold B. Gelb, Patrick Schöffski, Galit Rosen, Matthew H. Taylor, Andrea B. Apolo, John Allan Ellerton, Ding Wang, Carolyn D. Britten, Manish Agrawal, Manish R. Patel, Luc Dirix, Raid Aljumaliy
Publikováno v: Journal of Clinical Oncology. 35:330-330
330 Background: Avelumab is a fully human anti‒PD-L1 IgG1 antibody with promising efficacy and safety in patients (pts) with metastatic urothelial carcinoma (mUC). To further characterize the clinical activity of avelumab in mUC, we report a planne
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8c20f367e27e811574c42ffde33333e2
https://doi.org/10.1200/jco.2017.35.6_suppl.330
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