Diminished circadian and ultradian rhythms of human brain activity in pathological tissue in vivo

Autor: Christopher Thornton, Mariella Panagiotopoulou, Fahmida A. Chowdhury, Beate Diehl, John S. Duncan, Sarah J. Gascoigne, Guillermo Besne, Andrew W. McEvoy, Anna Miserocchi, Billy C. Smith, Jane de Tisi, Peter N. Taylor, Yujiang Wang

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-8 (2024)

Abstract Chronobiological rhythms, such as the circadian rhythm, have long been linked to neurological disorders, but it is currently unknown how pathological processes affect the expression of biological rhythms in the brain. Here, we use the unique

Externí odkaz: https://doaj.org/article/4ed27a28b92e4fa6b9502558c4f35dfa

Extent of piriform cortex resection in children with temporal lobe epilepsy

Autor: Rory J. Piper, Debayan Dasgupta, Maria H. Eriksson, Mathilde Ripart, Almira Moosa, Aswin Chari, Kiran K. Seunarine, Chris A. Clark, John S. Duncan, David W. Carmichael, Martin M. Tisdall, Torsten Baldeweg

Publikováno v: Annals of Clinical and Translational Neurology, Vol 10, Iss 9, Pp 1613-1622 (2023)

Abstract Objective A greater extent of resection of the temporal portion of the piriform cortex (PC) has been shown to be associated with higher likelihood of seizure freedom in adults undergoing anterior temporal lobe resection (ATLR) for drug‐res

Externí odkaz: https://doaj.org/article/5802949e23264f249a774122109c026f

Fishes associating with the echinoids Diadema setosum and Echinothrix calamaris (Diadematoida: Diadematidae) in the Phi Phi Islands of southwestern Thailand

Autor: Floyd E. Hayes, Madeline E. Eastman, John C. Duncan

Publikováno v: Journal of Asia-Pacific Biodiversity, Vol 16, Iss 3, Pp 300-305 (2023)

Many fish species are known to associate with echinoids. We studied the frequency of fishes associating with the diadematid Black Longspine Urchin Diadema setosum and Banded Sea Urchin Echinothrix calamaris in the Phi Phi Islands of southwestern Thai

Externí odkaz: https://doaj.org/article/1b34bb8c36174c2ba9a9ab69a1701739

Epileptogenic networks in extra temporal lobe epilepsy

Autor: Gerard R. Hall, Frances Hutchings, Jonathan Horsley, Callum M. Simpson, Yujiang Wang, Jane de Tisi, Anna Miserocchi, Andrew W. McEvoy, Sjoerd B. Vos, Gavin P. Winston, John S. Duncan, Peter N. Taylor

Publikováno v: Harvard Data Science Review, Vol 7, Iss 4 (2023)

Externí odkaz: https://doaj.org/article/0ebe4447b40d4712ae01b4994185bedd

Structural network alterations in focal and generalized epilepsy assessed in a worldwide ENIGMA study follow axes of epilepsy risk gene expression

Autor: Sara Larivière, Jessica Royer, Raúl Rodríguez-Cruces, Casey Paquola, Maria Eugenia Caligiuri, Antonio Gambardella, Luis Concha, Simon S. Keller, Fernando Cendes, Clarissa L. Yasuda, Leonardo Bonilha, Ezequiel Gleichgerrcht, Niels K. Focke, Martin Domin, Felix von Podewills, Soenke Langner, Christian Rummel, Roland Wiest, Pascal Martin, Raviteja Kotikalapudi, Terence J. O’Brien, Benjamin Sinclair, Lucy Vivash, Patricia M. Desmond, Elaine Lui, Anna Elisabetta Vaudano, Stefano Meletti, Manuela Tondelli, Saud Alhusaini, Colin P. Doherty, Gianpiero L. Cavalleri, Norman Delanty, Reetta Kälviäinen, Graeme D. Jackson, Magdalena Kowalczyk, Mario Mascalchi, Mira Semmelroch, Rhys H. Thomas, Hamid Soltanian-Zadeh, Esmaeil Davoodi-Bojd, Junsong Zhang, Gavin P. Winston, Aoife Griffin, Aditi Singh, Vijay K. Tiwari, Barbara A. K. Kreilkamp, Matteo Lenge, Renzo Guerrini, Khalid Hamandi, Sonya Foley, Theodor Rüber, Bernd Weber, Chantal Depondt, Julie Absil, Sarah J. A. Carr, Eugenio Abela, Mark P. Richardson, Orrin Devinsky, Mariasavina Severino, Pasquale Striano, Domenico Tortora, Erik Kaestner, Sean N. Hatton, Sjoerd B. Vos, Lorenzo Caciagli, John S. Duncan, Christopher D. Whelan, Paul M. Thompson, Sanjay M. Sisodiya, Andrea Bernasconi, Angelo Labate, Carrie R. McDonald, Neda Bernasconi, Boris C. Bernhardt

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)

Epilepsy is a brain network disorder with associated genetic risk factors. Here, the authors show that spatial patterns of transcriptomic vulnerability co-vary with structural brain network alterations in focal and generalized epilepsy.

Externí odkaz: https://doaj.org/article/42a2adc39a114a5faf720bcffa41fabd