Zobrazeno 1 - 10
of 217
pro vyhledávání: '"John A Crane"'
Publikováno v:
Biomolecules, Vol 14, Iss 3, p 321 (2024)
Our laboratory recently reported that induction of the SOS response, triggered by SOS-inducing drugs, was accompanied by a large release of DNA from enteric bacteria. The SOS response release had not previously been reported to include release of ext
Externí odkaz:
https://doaj.org/article/35e76be68a1b4a4ebc2e27ba07a48364
Autor:
John K. Crane, Marissa N. Catanzaro
Publikováno v:
Antibiotics, Vol 12, Iss 4, p 649 (2023)
The SOS response is a conserved stress response pathway that is triggered by DNA damage in the bacterial cell. Activation of this pathway can, in turn, cause the rapid appearance of new mutations, sometimes called hypermutation. We compared the abili
Externí odkaz:
https://doaj.org/article/fe5cdfb681454fa888855a4b14eebafe
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
BackgroundPrevious reports have differed as to whether nitric oxide inhibits or stimulates the SOS response, a bacterial stress response that is often triggered by DNA damage. The SOS response is an important regulator of production of Shiga toxins (
Externí odkaz:
https://doaj.org/article/0d40dbd00265475aa61fb38ca3a0bfd9
Publikováno v:
Metabolites, Vol 11, Iss 12, p 841 (2021)
Colonic epithelium–commensal interactions play a very important role in human health and disease development. Colonic mucus serves as an ecologic niche for a myriad of commensals and provides a physical barrier between the epithelium and luminal co
Externí odkaz:
https://doaj.org/article/96a1ea0ca20e4621802aed04150e83c4
Publikováno v:
Toxins, Vol 13, Iss 7, p 437 (2021)
Several classes of non-antibiotic drugs, including psychoactive drugs, proton-pump inhibitors (PPIs), non-steroidal anti-inflammatory drugs (NSAIDs), and others, appear to have strong antimicrobial properties. We considered whether psychoactive drugs
Externí odkaz:
https://doaj.org/article/39a37eef36c44221a5fec9eb895c734b
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 8 (2018)
The SOS response is a conserved response to DNA damage that is found in Gram-negative and Gram-positive bacteria. When DNA damage is sustained and severe, activation of error-prone DNA polymerases can induce a higher mutation rate than is normally ob
Externí odkaz:
https://doaj.org/article/6cda7d1f36fd4ea4b41959610e2060aa
Autor:
Rupa R Patel, John S Crane, Julia López, Philip A Chan, Albert Y Liu, Rubabin Tooba, Aimee S James
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0209484 (2018)
Pre-exposure prophylaxis (PrEP) is effective in preventing HIV infections among men who have sex with men (MSM). PrEP uptake and adherence remain low and product preferences are unknown, especially among young African American MSM who are most at-ris
Externí odkaz:
https://doaj.org/article/8929318b369446fda5c1a2f52ab925d7
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0178303 (2017)
Zinc inhibits the virulence of diarrheagenic E. coli by inducing the envelope stress response and inhibiting the SOS response. The SOS response is triggered by damage to bacterial DNA. In Shiga-toxigenic E. coli, the SOS response strongly induces the
Externí odkaz:
https://doaj.org/article/17106d43cc184c719c6e76d98b9c521a
Autor:
Swati Bhargava, Thomas R. Duquin, Thomas Listopadzki, John K. Crane, Sara Diletti, K. Keely Boyle
Publikováno v:
Journal of Bone and Joint Infection
Journal of Bone and Joint Infection, Vol 5, Pp 187-197 (2020)
Journal of Bone and Joint Infection, Vol 5, Pp 187-197 (2020)
Introduction: Cutibacterium acnes is gaining recognition as a leading pathogen after orthopaedic shoulder procedures. Photodynamic therapy, a combination of light and a photosensitizer, has demonstrated antimicrobial activity against C. acnes in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa7dee5c4269ee58a3c4163ccb4d02ab
http://europepmc.org/articles/PMC7358969
http://europepmc.org/articles/PMC7358969
Autor:
Matthew A. Prantil, M. Hamamoto, John K. Crane, Wade H. Williams, John M. Halpin, Charles D. Orth, Richard A. Sacks, Janice K. Lawson, Lynn G. Seppala, Mark W. Bowers, Jean-Michel G. Di Nicola, David Alessi, Michael C. Rushford, R. Lowe-Webb, Francis X. Morrissey, M. J. Shaw, C. C. Widmayer, S. Herriot, Thomas E. Lanier, J. Thaddeus Salmon, John E. Heebner, Mark R. Hermann, T. Zobrist, Paul J. Wegner, Steven T. Yang, Alan D. Conder, Hoang T. Nguyen, L. Pelz, Constantin Haefner, Pascale Di Nicola, K. N. LaFortune, Ronald J. Sigurdsson, Charles D. Boley, D. Homoelle, Daniel H. Kalantar
Publikováno v:
Applied optics. 60(8)
The advanced radiographic capability (ARC) laser system, part of the National Ignition Facility (NIF) at Lawrence Livermore National Laboratory, is a short-pulse laser capability integrated into the NIF. The ARC is designed to provide adjustable puls
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc5c10c48771c83db4eeb0bd259f3b60
https://pubmed.ncbi.nlm.nih.gov/33690328
https://pubmed.ncbi.nlm.nih.gov/33690328