Zobrazeno 1 - 10
of 1 914
pro vyhledávání: '"John A Cooper"'
Autor:
Adam B Johnston, Denise M Hilton, Patrick McConnell, Britney Johnson, Meghan T Harris, Avital Simone, Gaya K Amarasinghe, John A Cooper, Bruce L Goode
Publikováno v:
eLife, Vol 7 (2018)
Cellular actin assembly is controlled at the barbed ends of actin filaments, where capping protein (CP) limits polymerization. Twinfilin is a conserved in vivo binding partner of CP, yet the significance of this interaction has remained a mystery. He
Externí odkaz:
https://doaj.org/article/c72c9ada30584f3ba0551c6574cbb83b
Autor:
Suranjana Mukherjee, Joanna Kim, Olivia L Mooren, Stefanie T Shahan, Megan Cohan, John A Cooper
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0118153 (2015)
Natural Killer (NK) cells perform many functions that depend on actin assembly, including adhesion, chemotaxis, lytic synapse assembly and cytolysis. HS1, the hematopoietic homolog of cortactin, binds to Arp2/3 complex and promotes actin assembly by
Externí odkaz:
https://doaj.org/article/b4353951dd954114a31f33f0dd170bf0
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e115472 (2014)
Uveal melanoma arises in the eye, and it spreads to distant organs in almost half of patients, leading to a fatal outcome. To metastasize, uveal melanoma cells must transmigrate into and out of the microvasculature, crossing the monolayer of endothel
Externí odkaz:
https://doaj.org/article/6bb03c124c554e118f33b759a361023d
Autor:
Amanda E Siglin, Shangjin Sun, Jeffrey K Moore, Sarah Tan, Martin Poenie, James D Lear, Tatyana Polenova, John A Cooper, John C Williams
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e59453 (2013)
Cytoplasmic dynein and dynactin participate in retrograde transport of organelles, checkpoint signaling and cell division. The principal subunits that mediate this interaction are the dynein intermediate chain (IC) and the dynactin p150(Glued); howev
Externí odkaz:
https://doaj.org/article/68e8f2115ad140cfaefc02fb6de3eb24
Publikováno v:
ACS Omega, Vol 9, Iss 1, Pp 1310-1319 (2023)
Externí odkaz:
https://doaj.org/article/faf769cb0d0c46ddaa2097e700ccddfe
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e36127 (2012)
The spindle position checkpoint (SPC) ensures correct mitotic spindle position before allowing mitotic exit in the budding yeast Saccharomyces cerevisiae. In a candidate screen for checkpoint genes, we identified bud2Δ as deficient for the SPC. Bud2
Externí odkaz:
https://doaj.org/article/ac5fa4b30dbb456ba55f4a12c5135376
Publikováno v:
PLoS Biology, Vol 6, Iss 1, p e1 (2008)
The Arp2/3 complex is essential for actin assembly and motility in many cell processes, and a large number of proteins have been found to bind and regulate it in vitro. A critical challenge is to understand the actions of these proteins in cells, esp
Externí odkaz:
https://doaj.org/article/f56c00d0c74c45f5b51923ffce812105
Autor:
Anne Karen Jenum, Sverre Sandberg, Jørund Straand, Tore Julsrud Berg, Tor Claudi, Kjersti Nøkleby, Katrina Tibballs, Esben Selmer Buhl, John Graham Cooper, Lars Kirkebøen
Publikováno v:
BMJ Open Diabetes Research & Care, Vol 12, Iss 1 (2024)
Introduction People with young-onset type 2 diabetes (YOD), defined as diabetes diagnosis before age 40, have a high lifetime risk of vascular complications. We aimed to estimate the prevalence of YOD among adults with type 2 diabetes (T2D) in Norweg
Externí odkaz:
https://doaj.org/article/8bed929648e84b289ced00130ed8f70f
Autor:
Megan Stout, Tasha Posid, Jennifer Ballinger, John L. Cooper, Emily McKesson, Justin Rose, Cheryl T. Lee, Fara Bellows
Publikováno v:
Urology. 169:35-40
To develop a novel "bootcamp" simulation-based curriculum to introduce common urologic procedures and to improve readiness for performing them at bedside.Three hundred twenty-five third-year medical students at our single institution participated in
Autor:
Ukkyo Jeong, Si-Chee Tsay, N. Christina Hsu, David M. Giles, John W. Cooper, Jaehwa Lee, Robert J. Swap, Brent N. Holben, James J. Butler, Sheng-Hsiang Wang, Somporn Chantara, Hyunkee Hong, Donghee Kim, Jhoon Kim
Publikováno v:
Atmospheric Chemistry and Physics. 22:11957-11986
With the advent of spaceborne spectroradiometers in a geostationary constellation, measuring high spectral resolution ultraviolet–visible (UV-VIS) and selected near-/shortwave-infrared (NIR/SWIR) radiances can enable the probing of the life cycle o