Zobrazeno 1 - 6
of 6
pro vyhledávání: '"John A Chukinas"'
Autor:
Haiying Qin, Nirali N Shah, Terry J Fry, Lila Yang, John A Chukinas, Samiksha Tarun, Marie Pouzolles, Christopher D Chien, Lisa M Niswander, Anthony R Welch, Sarah K Tasian, Naomi A Taylor
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 9 (2021)
Externí odkaz:
https://doaj.org/article/7341e3e04ef748e4ab7d4e2752aa2b98
Autor:
Lisa M. Niswander, Zachary T. Graff, Christopher D. Chien, John A. Chukinas, Christina A. Meadows, Lillie C. Leach, Joseph P. Loftus, M. Eric Kohler, Sarah K. Tasian, Terry J. Fry
Publikováno v:
Haematologica, Vol 108, Iss 2 (2022)
Chimeric antigen receptor (CAR) T-cell immunotherapies targeting CD19 or CD22 induce remissions in the majority of patients with relapsed/refractory B-cell acute lymphoblastic leukemia (ALL), although relapse due to target antigen loss or downregulat
Externí odkaz:
https://doaj.org/article/a5805048705444a4ba59c1b09eba9327
Autor:
Tina Glisovic-Aplenc, Caroline Diorio, John A Chukinas, Kimberly Veliz, Olga Shestova, Feng Shen, Selene Nunez-Cruz, Tiffaney L Vincent, Fei Miao, Michael C Milone, Carl H June, David T Teachey, Sarah K Tasian, Richard Aplenc, Saar I. Gill
Publikováno v:
Blood Advances.
Many patients with hematologic malignancies are not curable with chemotherapy and require novel therapeutic approaches. Chimeric antigen receptor (CAR) T cell therapy is one such approach that involves the transfer of T cells engineered to express CA
Autor:
Bogdan Popescu, Carlos Stahlhut, Theodore C. Tarver, Sydney Wishner, Bianca J. Lee, Cheryl A. C. Peretz, Cuyler Luck, Paul Phojanakong, Juan Antonio Camara Serrano, Henry Hongo, Jose M. Rivera, Simayijiang Xirenayi, John A. Chukinas, Veronica Steri, Sarah K. Tasian, Elliot Stieglitz, Catherine C. Smith
Mutations in receptor tyrosine kinases (RTKs) FLT3 and KIT are frequent and associated with poor outcomes in acute myeloid leukemia (AML). Although FLT3 inhibitors (FLT3i) are clinically effective, remissions are short-lived due to secondary resistan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49ae1ee8377a977fdca83b311ef68dda
https://doi.org/10.1101/2022.12.01.518665
https://doi.org/10.1101/2022.12.01.518665
Autor:
Christian Hurtz, V. S. S. Abhinav Ayyadevara, Gerald Wertheim, John A Chukinas, Joseph P Loftus, Sung June Lee, Anil Kumar, Rahul S Bhansali, Srividya Swaminathan, Huimin Geng, Thomas Milne, Xianxin Hua, Kathrin M Bernt, Thierry Besson, Junwei Shi, John D. Crispino, Martin Carroll, Sarah K Tasian
KMT2A-rearranged (KMT2A-R) B cell acute lymphoblastic leukemia (ALL) is a high-risk disease in children and adults that is often chemotherapy resistant. To identify non-cytotoxic approaches to therapy, we performed a domain-specific kinome-wide CRISP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::677be1549818dcc63405a7c495ef833f
https://doi.org/10.1101/2022.10.02.510349
https://doi.org/10.1101/2022.10.02.510349
Autor:
Sisi Zheng, Elisabeth Gillespie, Ammar S. Naqvi, Katharina E. Hayer, Zhiwei Ang, Manuel Torres-Diz, Mathieu Quesnel-Vallières, David A. Hottman, Asen Bagashev, John A. Chukinas, Carolin Schmidt, Mukta Mukta Asnani, Rawan Shraim, Deanne M. Taylor, Susan R. Rheingold, Maureen M. O’Brien, Nathan Singh, Kristen W. Lynch, Marco Ruella, Yoseph Barash, Sarah K. Tasian, Andrei Thomas-Tikhonenko
Publikováno v:
Cancer Research. 82:6248-6248
Downregulation of surface epitopes causes post-immunotherapy relapses in B-lymphoblastic leukemia (B-ALL). Here we demonstrate that mRNA encoding CD22 undergoes aberrant splicing in B-ALL. We describe the plasma-membrane-bound CD22 Δex5-6 splice iso