Zobrazeno 1 - 10
of 49
pro vyhledávání: '"John A Bukowski"'
Publikováno v:
Epigenetic Drug Discovery. :263-296
Autor:
Juergen H Nett, W James Cook, Ming-Tang Chen, Robert C Davidson, Piotr Bobrowicz, Warren Kett, Elena Brevnova, Thomas I Potgieter, Mark T Mellon, Bianka Prinz, Byung-Kwon Choi, Dongxing Zha, Irina Burnina, John T Bukowski, Min Du, Stefan Wildt, Stephen R Hamilton
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68325 (2013)
The methylotrophic yeast, Pichiapastoris, is an important organism used for the production of therapeutic proteins. However, the presence of fungal-like glycans, either N-linked or O-linked, can elicit an immune response or enable the expressed prote
Externí odkaz:
https://doaj.org/article/430da7bedc8648048bd5e05cd1244467
Autor:
John A. Bukowski, R. Jeffrey Lewis
Publikováno v:
Dose-Response, Vol 2 (2004)
Cancer and noncancer health effects have traditionally been handled differently in quantitative risk assessment. A threshold (i.e., safe exposure) has been assumed for noncancer health effects, and low-dose linearity without a threshold has been assu
Externí odkaz:
https://doaj.org/article/f5594a438e4947f1a43d6f6e5f99ad60
Autor:
John A. Bukowski, R. Jeffrey Lewis
Publikováno v:
Dose-Response, Vol 1 (2003)
The “hygiene hypothesis” has been suggested to explain the rising incidence of allergic disorders in developed countries. The postulated mechanism is that infectious and/or microbial agents stimulate the immune system toward Th1 (allergy fighting
Externí odkaz:
https://doaj.org/article/41264a8155a34b12a0a5186d48218f2f
Publikováno v:
Methods and Principles in Medicinal Chemistry ISBN: 9783527343140
Epigenetic Drug Discovery
Epigenetic Drug Discovery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71fb3d702c186e854731a553dd0695dc
https://doi.org/10.1002/9783527809257
https://doi.org/10.1002/9783527809257
Autor:
John A Bukowski
Publikováno v:
Critical Reviews in Toxicology. 44:581-589
The most recent Integrated Risk Information System review of trichloroethylene (TCE; CAS# 79-01-6) has suggested that congenital heart defects (CHD) are a critical endpoint associated with exposure to this solvent. This conclusion was drawn, at least
Autor:
Leonardo D. Gomez, Simon J. McQueen-Mason, Simon R. Turner, Paul Dupree, Raymond Wightman, Ivan Atanassov, Theodora Tryfona, David Brown, Zhinong Zhang, John Paul Bukowski
Publikováno v:
The Plant Journal. 66:401-413
There are 10 genes in the Arabidopsis genome that contain a domain described in the Pfam database as domain of unknown function 579 (DUF579). Although DUF579 is widely distributed in eukaryotic species, there is no direct experimental evidence to ass
Autor:
John Paul Bukowski, Jens Vilstrup Johansen, Diego Pasini, Kristian Helin, Mads Bak, Juri Rappsilber, Julian Walfridsson, Paul A. C. Cloos, Linda Olsson, Niels Tommerup
Publikováno v:
Nature. 464:306-310
Polycomb proteins have a key role in regulating the expression of genes essential for development, differentiation and maintenance of cell fates. Here, Polycomb repressive complex 2 (PRC2) is shown to form a complex with JARID2, a Jumonji domain prot
Autor:
John F. Bukowski
Publikováno v:
The College Mathematics Journal. 39:2-11
John Bukowski (bukowski@juniata.edu) is Associate Professor and Chair of the Department of Mathematics at Juniata College in Huntingdon, Pennsylvania. He received B.S. degrees in mathematics and physics from Carnegie Mellon University and his Ph.D. i
Autor:
Panagiotis Karahalios, Tanya V. Aspinall, James M B Gordon, John Paul Bukowski, Johanna M. Avis, Hayley J. Bennett, Scott C. Walker, David R. Engelke
Publikováno v:
Nucleic Acids Research
Ribonuclease MRP is an endonuclease, related to RNase P, which functions in eukaryotic pre-rRNA processing. In Saccharomyces cerevisiae, RNase MRP comprises an RNA subunit and ten proteins. To improve our understanding of subunit roles and enzyme arc