Zobrazeno 1 - 10
of 213
pro vyhledávání: '"John A, Rudd"'
Autor:
Xiaoyan Zeng, Stanley K. K. Cheung, Mengqi Shi, Penelope M. Y. Or, Zhining Li, Julia Y. H. Liu, Wayne L. H. Ho, Tian Liu, Kun Lu, John A. Rudd, Yubing Wang, Andrew M. Chan
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-15 (2023)
Abstract Glial cell-mediated neuroinflammation and neuronal attrition are highly correlated with cognitive impairment in Alzheimer’s disease. YKL-40 is a secreted astrocytic glycoprotein that serves as a diagnostic biomarker of Alzheimer’s diseas
Externí odkaz:
https://doaj.org/article/79608af6e94043fcab68f7bde85cf7d2
Autor:
Julia Yuen Hang Liu, John A. Rudd
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Electrical data could be a new source of big-data for training artificial intelligence (AI) for drug discovery. A Gastro-Intestinal Pacemaker Activity Drug Database (GIPADD) was built using a standardized methodology to test drug effects on
Externí odkaz:
https://doaj.org/article/4354f9ca54ea48d6a488fa92bd2b25ab
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/a8921536b38a423abb5fc4587d73c21d
Autor:
Zengbing Lu, Dexuan Cui, Julia Yuen Hang Liu, Bin Jiang, Man Piu Ngan, Ichiro Sakata, Shota Takemi, Takafumi Sakai, Ge Lin, Sze Wa Chan, John A. Rudd
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Nesfatin-1 is an anorectic peptide expressed in both peripheral tissues and brain areas involved in the regulation of feeding, emotion and emesis. The aim of the present study is to characterize the distribution of NUCB2/nesfatin-1 in Suncus murinus
Externí odkaz:
https://doaj.org/article/d091dca41fe445fd9e24ac708193605e
Autor:
Halina Was, Agata Borkowska, Ana Bagues, Longlong Tu, Julia Y. H. Liu, Zengbing Lu, John A. Rudd, Kulmira Nurgali, Raquel Abalo
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Since the first clinical trials conducted after World War II, chemotherapeutic drugs have been extensively used in the clinic as the main cancer treatment either alone or as an adjuvant therapy before and after surgery. Although the use of chemothera
Externí odkaz:
https://doaj.org/article/7a7c8e413862400ba203fff0bda99f63
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Purpose: Cancer patients receiving cisplatin therapy often experience side-effects such as nausea and emesis, but current anti-emetic regimens are suboptimal. Thus, to enable the development of efficacious anti-emetic treatments, the mechanisms of ci
Externí odkaz:
https://doaj.org/article/9631b9b9e0584f3dbfdfcffe5906cc31
Autor:
Zengbing Lu, Yu Zhou, Longlong Tu, Sze Wa Chan, Man P. Ngan, Dexuan Cui, Yuen Hang Julia Liu, Ianto Bosheng Huang, Jeng S. C. Kung, Chung Man Jessica Hui, John A. Rudd
Publikováno v:
Frontiers in Physiology, Vol 11 (2021)
Nausea and emesis resulting from disease or drug treatment may be associated with disrupted gastric myoelectric activity (GMA). Conventional analytical techniques can determine the relative degrees of brady-, normo-, and tachygastric power, but lose
Externí odkaz:
https://doaj.org/article/1bd3840da96441499db880ff785da2bb
Publikováno v:
Journal of Pharmacological Sciences, Vol 133, Iss 4, Pp 232-239 (2017)
Bacopa monnieri (BM, family Scrophulariaceae) is used in several traditional systems of medicine for the management of epilepsy, depression, neuropathic pain, sleep disorders and memory deficits. The present study investigated the potential of BM met
Externí odkaz:
https://doaj.org/article/9f3f8d3378cd4b58b599915291967a0e
Autor:
On-Chai Lau, Bing Shen, Ching-On Wong, Yung-Wui Tjong, Chun-Yin Lo, Hui-Chuan Wang, Yu Huang, Wing-Ho Yung, Yang-Chao Chen, Man-Lung Fung, John Anthony Rudd, Xiaoqiang Yao
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
The identity of mechanosensors within aortic baroreceptors that sense fluctuations in blood pressure is unclear. Here, Lau et al.show that a cation channel TRPC5 acts as a transducer of mechanical stimuli in aortic baroreceptor neurons in rodents.
Externí odkaz:
https://doaj.org/article/6043789188ed4256af354756dca532c6
Autor:
John A. Rudd, Sze W. Chan, Man P. Ngan, Longlong Tu, Zengbing Lu, Claudio Giuliano, Emanuela Lovati, Claudio Pietra
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Externí odkaz:
https://doaj.org/article/f68a76d710fc4a929a561e4f371caa02