Zobrazeno 1 - 10
of 2 330
pro vyhledávání: '"John A, McGrath"'
Autor:
Joeri Meijsen, Kejia Hu, Morten D. Krebs, Georgios Athanasiadis, Sarah Washbrook, Richard Zetterberg, Raquel Nogueira Avelar e Silva, John R. Shorter, Jesper R. Gådin, Jacob Bergstedt, David M. Howard, Weimin Ye, Yi Lu, Unnur A. Valdimarsdóttir, Andrés Ingason, Dorte Helenius, Oleguer Plana-Ripoll, John J. McGrath, Nadia Micali, Ole A. Andreassen, Thomas M. Werge, Fang Fang, Alfonso Buil
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Mental disorders are leading causes of disability and premature death worldwide, partly due to high comorbidity with cardiometabolic disorders. Reasons for this comorbidity are still poorly understood. We leverage nation-wide health records
Externí odkaz:
https://doaj.org/article/b590855b0172469c974a0c55e5a42e1d
Autor:
Grace Tartaglia, Ignacia Fuentes, Neil Patel, Abigail Varughese, Lauren E Israel, Pyung Hun Park, Michael H Alexander, Shiv Poojan, Qingqing Cao, Brenda Solomon, Zachary M Padron, Jonathan A Dyer, Jemima E Mellerio, John A McGrath, Francis Palisson, Julio Salas-Alanis, Lin Han, Andrew P South
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 4, Pp 870-884 (2024)
Abstract Recessive dystrophic epidermolysis bullosa (RDEB) is a rare inherited skin disease characterized by defects in type VII collagen leading to a range of fibrotic pathologies resulting from skin fragility, aberrant wound healing, and altered de
Externí odkaz:
https://doaj.org/article/68b1c43ece124fbe9f6ab1f212aefc96
Autor:
John J. McGrath
Publikováno v:
International Journal of Methods in Psychiatric Research, Vol 33, Iss S1, Pp n/a-n/a (2024)
Externí odkaz:
https://doaj.org/article/99559bb0918b4f4cab187f7484c2680e
Autor:
Yi-Kai Hong, Yu-Chen Lin, Tsung-Lin Cheng, Chao-Han Lai, Yi-Han Chang, Yu-Lun Huang, Chia-Yi Hung, Chen-Han Wu, Kuo-Shu Hung, Ya-Chu Ku, Yen-Ting Ho, Ming-Jer Tang, Shu-Wha Lin, Guey-Yueh Shi, John A. McGrath, Hua-Lin Wu, Chao-Kai Hsu
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-25 (2024)
Abstract Background Pathologic scars, including keloids and hypertrophic scars, represent a common form of exaggerated cutaneous scarring that is difficult to prevent or treat effectively. Additionally, the pathobiology of pathologic scars remains po
Externí odkaz:
https://doaj.org/article/0668ee67d3c444a6ab6d5c3bd3c22df6
Publikováno v:
Human Genomics, Vol 17, Iss 1, Pp 1-24 (2023)
Abstract Background Alternative splicing (AS) plays a crucial role in transcriptomic diversity and is a hallmark of cancer that profoundly influences the development and progression of prostate cancer (PCa), a prevalent and potentially life-limiting
Externí odkaz:
https://doaj.org/article/a018ef0f11b7414cb1688e0006461cf1
Autor:
Ymkje Anna deVries, Jordi Alonso, Somnath Chatterji, Peter deJonge, Joran Lokkerbol, John J. McGrath, Maria V. Petukhova, Nancy A. Sampson, Erik Sverdrup, Daniel V. Vigo, Stefan Wager, Ali Al‐Hamzawi, Guilherme Borges, Ronny Bruffaerts, Brendan Bunting, Stephanie Chardoul, Elie G. Karam, Andrzej Kiejna, Viviane Kovess‐Masfety, Fernando Navarro‐Mateu, Akin Ojagbemi, Marina Piazza, José Posada‐Villa, Carmen Sasu, Kate M. Scott, Hisateru Tachimori, Margreet Ten Have, Yolanda Torres, Maria Carmen Viana, Manuel Zamparini, Zahari Zarkov, Ronald C. Kessler, World Mental Health Survey Collaborators
Publikováno v:
International Journal of Methods in Psychiatric Research, Vol 33, Iss 1, Pp n/a-n/a (2024)
Abstract Objective The standard method of generating disorder‐specific disability scores has lay raters make rankings between pairs of disorders based on brief disorder vignettes. This method introduces bias due to differential rater knowledge of d
Externí odkaz:
https://doaj.org/article/141212e3f5624a249f0eab1f5192b31e
Autor:
Cian J.H. Horneck Johnston, Anna E. Ledwith, Mimmi L.E. Lundahl, Hugo Charles-Messance, Emer E. Hackett, Simon D. O’Shaughnessy, Jonah Clegg, Hannah Prendeville, John P. McGrath, Aaron M. Walsh, Sarah Case, Hollie Austen Byrne, Parth Gautam, Elaine Dempsey, Sinead C. Corr, Frederick J. Sheedy
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109030- (2024)
Summary: Fungal β-glucans are major drivers of trained immunity which increases long-term protection against secondary infections. Heterogeneity in β-glucan source, structure, and solubility alters interaction with the phagocytic receptor Dectin-1
Externí odkaz:
https://doaj.org/article/a82f686f0bfb42e89b2067f61614d09d
Autor:
Sandra Ropret, Preeti Khurana, Tara Fabčič, Janina Cvetkovska, Ana Trobec, Špela Zemljič Jokhadar, Dusko Ilic, John A McGrath, Christina Guttmann-Gruber, Mirjana Liovic
Publikováno v:
Stem Cell Research, Vol 75, Iss , Pp 103306- (2024)
We have generated MLi005-A, a new induced pluripotent stem cell (iPSC) line derived from skin fibroblasts of a male patient with dominant dystrophic epidermolysis bullosa (DDEB). This iPSC line may be used as a model system for studies on skin integr
Externí odkaz:
https://doaj.org/article/0198e37ce12b4be5b5a84037ebc9f8ca
Autor:
Emil M. Pedersen, Esben Agerbo, Oleguer Plana-Ripoll, Jette Steinbach, Morten D. Krebs, David M. Hougaard, Thomas Werge, Merete Nordentoft, Anders D. Børglum, Katherine L. Musliner, Andrea Ganna, Andrew J. Schork, Preben B. Mortensen, John J. McGrath, Florian Privé, Bjarni J. Vilhjálmsson
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Proportional hazards models have been proposed to analyse time-to-event phenotypes in genome-wide association studies (GWAS). However, little is known about the ability of proportional hazards models to identify genetic associations under di
Externí odkaz:
https://doaj.org/article/eb3d95affd73451ea109b0d277fe474f
Itch in recessive dystrophic epidermolysis bullosa: findings of PEBLES, a prospective register study
Autor:
Jemima E. Mellerio, Elizabeth I. Pillay, Lesedi Ledwaba-Chapman, Alessandra Bisquera, Susan J. Robertson, Marieta Papanikolaou, John A. McGrath, Yanzhong Wang, Anna E. Martinez, Eunice Jeffs
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 18, Iss 1, Pp 1-10 (2023)
Abstract Background Itch is common and distressing in epidermolysis bullosa (EB) but has not previously been studied in depth in different recessive dystrophic EB (RDEB) subtypes. Objectives As part of a prospective register study of the natural hist
Externí odkaz:
https://doaj.org/article/fffd1c42edb4449fa70ef4bb51e829bf