Zobrazeno 1 - 10
of 107
pro vyhledávání: '"John A, Mackintosh"'
Publikováno v:
Respirology Case Reports, Vol 12, Iss 9, Pp n/a-n/a (2024)
Abstract VEXAS (Vacuoles, E1 enzyme, X‐linked, Autoinflammatory, Somatic) syndrome is a rare and recently identified disease resulting from a somatic mutation in the X‐linked UBA1 gene in cells of myeloid lineage. It can present in a myriad of wa
Externí odkaz:
https://doaj.org/article/0de0aa8486ae4532b956f3d972e8b379
Autor:
Samantha Chin‐Yun Kung, Olivia Dixon, Sarah Kentwell, Raja S. Vasireddy, Jonathan Rodgers, Yuming Ding, Tony Rahman, Caroline Tallis, Ian A. Yang, John A. Mackintosh
Publikováno v:
Respirology Case Reports, Vol 11, Iss 8, Pp n/a-n/a (2023)
Abstract A 33‐year‐old man presented with acute dyspnoea and profound hypoxaemia, and had clubbing, greying of hair, orthodeoxia and fine inspiratory crackles. CT chest showed established pulmonary fibrosis in a usual interstitial pneumonia patte
Externí odkaz:
https://doaj.org/article/4f005229bf8e49679982419de20a0c87
Autor:
Theresia A. Mikolasch, Peter M. George, Jagdeep Sahota, Thomas Nancarrow, Shaney L. Barratt, Felix A. Woodhead, Vasilis Kouranos, Victoria S.A. Cope, Andrew W. Creamer, Silan Fidan, Balaji Ganeshan, Luke Hoy, John A. Mackintosh, Robert Shortman, Anna Duckworth, Janet Fallon, Helen Garthwaite, Melissa Heightman, Huzaifa I. Adamali, Sarah Lines, Thida Win, Rebecca Wollerton, Elisabetta A. Renzoni, Matthew Steward, Athol U. Wells, Michael Gibbons, Ashley M. Groves, Bibek Gooptu, Chris J. Scotton, Joanna C. Porter
Publikováno v:
EClinicalMedicine, Vol 55, Iss , Pp 101758- (2023)
Summary: Background: Idiopathic pulmonary fibrosis (IPF) is a progressive, fatal disorder with a variable disease trajectory. The aim of this study was to assess the potential of neutrophil-to-lymphocyte ratio (NLR) to predict outcomes in IPF. Method
Externí odkaz:
https://doaj.org/article/85fa843c585542cbaba15e6d4040db5d
Autor:
John A. Mackintosh, Athol U. Wells, Vincent Cottin, Andrew G. Nicholson, Elisabetta A. Renzoni
Publikováno v:
European Respiratory Review, Vol 30, Iss 162 (2021)
The presence of clinical, serological and/or radiological features suggestive, but not confirmatory, of a defined connective tissue disease in patients with interstitial lung disease is a relatively frequent occurrence. In 2015, the European Respirat
Externí odkaz:
https://doaj.org/article/70b74619c4c04d038e5ded7ac8303f5f
Autor:
John A. Mackintosh, Stephanie T. Yerkovich, Maxine E. Tan, Luke Samson, Peter MA Hopkins, Daniel C. Chambers
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
IntroductionChronic lung allograft dysfunction (CLAD) represents the major impediment to long term survival following lung transplantation. Donor and recipient telomere length have been shown to associate with lung transplant outcomes, including CLAD
Externí odkaz:
https://doaj.org/article/8e8000e7deb044489c76ac1ae51634ad
Autor:
Tamera J Corte, Adam Jaffe, Christopher Grainge, Jeremy Wrobel, Hiran Selvadurai, Stephanie T Yerkovich, Daniel C Chambers, Maxine Tan, Ian Glaspole, Peter Hopkins, Paul N Reynolds, Hilda A Pickett, Nicole S Goh, John A Mackintosh, Maria Pietsch, Viviana Lutzky, Debra Enever, Sandra Bancroft, Simon H Apte, Joanne L Dickinson
Publikováno v:
BMJ Open Respiratory Research, Vol 8, Iss 1 (2021)
Introduction Recent discoveries have identified shortened telomeres and related mutations in people with pulmonary fibrosis (PF). There is evidence to suggest that androgens, including danazol, may be effective in lengthening telomeres in peripheral
Externí odkaz:
https://doaj.org/article/d78f24442db3416a88dff94c49697f59
Autor:
Hayley, Barnes, Stephen M, Humphries, Peter M, George, Deborah, Assayag, Ian, Glaspole, John A, Mackintosh, Tamera J, Corte, Marilyn, Glassberg, Kerri A, Johannson, Lucio, Calandriello, Federico, Felder, Athol, Wells, Simon, Walsh
Publikováno v:
The Lancet Digital Health. 5:e41-e50
Challenges for the effective management of interstitial lung diseases (ILDs) include difficulties with the early detection of disease, accurate prognostication with baseline data, and accurate and precise response to therapy. The purpose of this Revi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f29a2f7287bbb73734f27d70ab3c8802
https://doi.org/10.1016/s2589-7500(22)00230-8
https://doi.org/10.1016/s2589-7500(22)00230-8
Autor:
Stephen M. Humphries, John A. Mackintosh, Helen E. Jo, Simon L. F. Walsh, Mario Silva, Lucio Calandriello, Sally Chapman, Samantha Ellis, Ian Glaspole, Nicole Goh, Christopher Grainge, Peter M. A. Hopkins, Gregory J. Keir, Yuben Moodley, Paul N. Reynolds, E. Haydn Walters, David Baraghoshi, Athol U. Wells, David A. Lynch, Tamera J. Corte
Publikováno v:
Respirology. 27:1045-1053
Prediction of disease course in patients with progressive pulmonary fibrosis remains challenging. The purpose of this study was to assess the prognostic value of lung fibrosis extent quantified at computed tomography (CT) using data-driven texture an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2763d664b61cadce461256bd602bc4c0
https://doi.org/10.1111/resp.14333
https://doi.org/10.1111/resp.14333
Autor:
Alan M. Carew, John A. Mackintosh
Publikováno v:
J Thorac Dis
BACKGROUND: Tracheobronchial stents are often used to manage lung transplant airway complications. In 2005, the Food and Drug Administration (FDA) issued a warning against the use of metallic stents for benign airway disease. Since that time, fully c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35895756d81e3aa01ffbeb463a8482de
https://doi.org/10.21037/jtd-22-889
https://doi.org/10.21037/jtd-22-889
Autor:
John A. Mackintosh, Edwina E. Duhig, Taryn Reddy, Edward K.H. Stephens, Kwun M. Fong, Ian A. Yang
Publikováno v:
Lung Diseases and Cancer ISBN: 9781849841542
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84fbe97cd439bcba90d4ae540fb423e7
https://doi.org/10.1183/2312508x.10020221
https://doi.org/10.1183/2312508x.10020221
