Zobrazeno 1 - 10
of 161
pro vyhledávání: '"John A, Kalapurakal"'
Autor:
David C. Qian, Katherine D. Sykes-Martin, Rachel Tobillo, Naba Ali, Jacob F. Wynne, Bree R. Eaton, Arnold C. Paulino, John A. Kalapurakal, Natia Esiashvili
Publikováno v:
American Journal of Clinical Oncology. 46:213-218
Autor:
Peter J. Houghton, Raushan T. Kurmasheva, Sandeep Burma, C. David James, John A. Kalapurakal, Xiao-Nan Li, Mari Kogiso, Joel E. Michalek, Qianqian Liu, Adam Studebaker, Samson Ghilu, Kathryn M. Bondra, Fuyang Li
Supplementary Figure from Regulation of TORC1 by MAPK Signaling Determines Sensitivity and Acquired Resistance to Trametinib in Pediatric BRAFV600E Brain Tumor Models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1310b744238a8e21689b55acde746e76
https://doi.org/10.1158/1078-0432.22487310.v1
https://doi.org/10.1158/1078-0432.22487310.v1
Autor:
Peter J. Houghton, Raushan T. Kurmasheva, Sandeep Burma, C. David James, John A. Kalapurakal, Xiao-Nan Li, Mari Kogiso, Joel E. Michalek, Qianqian Liu, Adam Studebaker, Samson Ghilu, Kathryn M. Bondra, Fuyang Li
Purpose:We investigated why three patient-derived xenograft (PDX) childhood BRAFV600E-mutant brain tumor models are highly sensitive to trametinib. Mechanisms of acquired resistance selected in situ, and approaches to prevent resistance were also exa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c0409952db8fe60655f86ed6525282f
https://doi.org/10.1158/1078-0432.c.6532494.v1
https://doi.org/10.1158/1078-0432.c.6532494.v1
Autor:
Peter J. Houghton, Raushan T. Kurmasheva, Sandeep Burma, C. David James, John A. Kalapurakal, Xiao-Nan Li, Mari Kogiso, Joel E. Michalek, Qianqian Liu, Adam Studebaker, Samson Ghilu, Kathryn M. Bondra, Fuyang Li
Supplementary Data from Regulation of TORC1 by MAPK Signaling Determines Sensitivity and Acquired Resistance to Trametinib in Pediatric BRAFV600E Brain Tumor Models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84c57995b9ed7f95d6340ac250357331
https://doi.org/10.1158/1078-0432.22487337
https://doi.org/10.1158/1078-0432.22487337
Autor:
Peter J. Houghton, Raushan T. Kurmasheva, Sandeep Burma, C. David James, John A. Kalapurakal, Xiao-Nan Li, Mari Kogiso, Joel E. Michalek, Qianqian Liu, Adam Studebaker, Samson Ghilu, Kathryn M. Bondra, Fuyang Li
Supplementary Table from Regulation of TORC1 by MAPK Signaling Determines Sensitivity and Acquired Resistance to Trametinib in Pediatric BRAFV600E Brain Tumor Models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38510a681975e6bd8b5372e754e006ee
https://doi.org/10.1158/1078-0432.22487301
https://doi.org/10.1158/1078-0432.22487301
Autor:
Murali M. Chintagumpala, Elizabeth J. Perlman, Brett Tornwall, Yueh‐Yun Chi, Yeonil Kim, Fredric A. Hoffer, John A. Kalapurakal, Anne B. Warwick, Robert C. Shamberger, Geetika Khanna, Thomas E. Hamilton, Kenneth W. Gow, Arnold C. Paulino, Eric J. Gratias, Elizabeth A. Mullen, James I. Geller, Conrad V. Fernandez, Michael L. Ritchey, Paul E. Grundy, Jeffrey S. Dome, Peter F. Ehrlich
Publikováno v:
Cancer
An objective of the Children's Oncology Group AREN0534 Study was to improve the survival of patients with bilateral Wilms tumors (BWT) by using preoperative chemotherapy of limited duration and tailoring postoperative therapy based on histopathologic
Practice Patterns of Pediatric Total Body Irradiation Techniques: A Children's Oncology Group Survey
Autor:
Harish K. Malhotra, David S Followill, Iain MacEwan, John C. Breneman, Adam C. Olson, Thomas J. Fitzgerald, Fred K. Cheung, Mahesh Gopalakrishnan, Prema Rassiah, S Pillai, Karen J. Marcus, Greg Niyazov, Natia Esiashvili, Andrea Molineu, Arthur J. Olch, John A. Kalapurakal, Cheng-Chia Wu, Kenneth Ulin, Jacqueline Faught, Chia Ho Hua, Nataliya Kovalchuk, An Liu, Jose Penagaricano
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 111:1155-1164
Purpose The aim of this study was to examine current practice patterns in pediatric total body irradiation (TBI) techniques among COG member institutions. Methods and Materials Between November 2019 and February 2020, a questionnaire containing 52 qu
Autor:
Jeffrey S. Dome, Murali Chintagumpala, David Dix, Peter F. Ehrlich, Elizabeth Perlman, James I. Geller, Paul E. Grundy, Lindsay A. Renfro, Najat C. Daw, Eric J. Gratias, Geetika Khanna, John A. Kalapurakal, Conrad V. Fernandez, Elizabeth Mullen
Publikováno v:
J Natl Compr Canc Netw
Refinements in surgery, radiation therapy, and chemotherapy since the mid-20th century have resulted in a survival rate exceeding 90% for patients with Wilms tumor (WT). Although this figure is remarkable, a significant proportion of patients continu
Autor:
Sarah A. Milgrom, Matthew Hall, Susan M. Hiniker, Benjamin T. Cooper, J.C. Shiao, Alyssa Wojcik, Paige L. Dorn, Iain MacEwan, Joshua D. Palmer, Derek S. Tsang, Stephanie Surgener, Luke Pater, Nicole Boik, John T. Lucas, Samir Patel, John A. Kalapurakal, Adam C. Olson, Jennifer Vogel, Natalie Logie, Cheng-Chia Wu, John C. Breneman, Douglas E. Holt
Publikováno v:
Int J Radiat Oncol Biol Phys
PURPOSE/OBJECTIVES: Treatment with radiation therapy (RT) can cause anxiety and distress for pediatric patients and their families. Radiation oncology teams have developed strategies to reduce the negative psychological impact. This survey study aime
Autor:
Fuyang Li, Kathryn M. Bondra, Samson Ghilu, Adam Studebaker, Qianqian Liu, Joel E. Michalek, Mari Kogiso, Xiao-Nan Li, John A. Kalapurakal, C. David James, Sandeep Burma, Raushan T. Kurmasheva, Peter J. Houghton
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 28(17)
Purpose: We investigated why three patient-derived xenograft (PDX) childhood BRAFV600E-mutant brain tumor models are highly sensitive to trametinib. Mechanisms of acquired resistance selected in situ, and approaches to prevent resistance were also ex