Zobrazeno 1 - 10
of 59
pro vyhledávání: '"John Quilley"'
Autor:
Elisa Nesta, Pietro Minuz, John C. McGiff, G. Amen, Cristiano Fava, John Quilley, Giovanni Zanconato, Houli Jiang
Publikováno v:
American Journal of Hypertension. 26:271-278
Preeclampsia is a severe disorder of pregnancy characterized by the development of hypertension and proteinuria, in which increased vascular resistance and endothelial dysfunction in the mother are often accompanied by altered placental perfusion and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fc5a5a37dc8e3dfb4fc26d9617ab846
https://doi.org/10.1093/ajh/hps011
https://doi.org/10.1093/ajh/hps011
Autor:
Matteo Brunelli, Houli Jiang, Francesco Dalle Vedove, Gaetano Vattemi, Cristiano Fava, Valeria Guglielmi, Pietro Minuz, John Quilley, Giovanni Zanconato
BACKGROUND Epoxyeicosatrienoic acids (EETs) derived from cytochrome P450 (CYP)-dependent metabolism of arachidonic acid are increased in the plasma of women with preeclampsia as compared with normal pregnancy and are significantly higher in fetal tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::362c2f942c6e18eb6a6ceb89095437da
http://hdl.handle.net/11562/945226
http://hdl.handle.net/11562/945226
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 294:H2305-H2312
We confirmed that release of 20-hydroxyeicosatetraenoic acid (20-HETE) from the isolated perfused kidney of diabetic rats is greatly reduced compared with age-matched control rats. The present studies were undertaken to examine potential mechanisms f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdb7afdaab53fb37b4b3d74c70e044d0
https://doi.org/10.1152/ajpheart.00868.2007
https://doi.org/10.1152/ajpheart.00868.2007
Autor:
John Quilley, Yu-Jung Chen
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 324:658-663
Renal cyclooxygenase (COX)-2 expression is increased in the diabetic rat and has been linked to increased glomerular filtration rate (GFR) and renal injury. Our studies indicate that oxidative stress in the form of peroxynitrite (ONOO) may be the sti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::822acd349937e83719ea1d9eab4f1d7b
https://doi.org/10.1124/jpet.107.129197
https://doi.org/10.1124/jpet.107.129197
Effect of Tempol on Renal Cyclooxygenase Expression and Activity in Experimental Diabetes in the Rat
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 314:818-824
Renal cyclooxygenase (COX)-2 expression is increased in the streptozotocin (STZ)-diabetic rat and is associated with enhanced renal prostaglandin release in response to arachidonic acid (AA). Endoperoxide-mediated vasoconstrictor responses to AA were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::772f41eb32c5317cff48670136845b04
https://doi.org/10.1124/jpet.104.076927
https://doi.org/10.1124/jpet.104.076927
Autor:
Yue Qiu, John Quilley
Publikováno v:
European Journal of Pharmacology. 508:193-199
Increased extracellular K + is reported to cause endothelium-independent vasodilation and K + has been proposed as an endothelium-derived hyperpolarizing factor. However, the endothelium is endowed with K + channels that may also be responsive to inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6e682bf191312fe12a4d6bbc7bb1631
https://doi.org/10.1016/j.ejphar.2004.12.025
https://doi.org/10.1016/j.ejphar.2004.12.025
Autor:
Houli Jiang, John C. McGiff, John Quilley, L. Manmohan Reddy, John R. Falck, Patrick Y.-K. Wong
Publikováno v:
Prostaglandins & Other Lipid Mediators. 75:65-78
Epoxyeicosatrienoic acids (EETs) are candidate endothelium-derived hyperpolarizing factors that demonstrate a wide range of biological effects. The presence of both cis - and trans -EETs in rat plasma was identified with HPLC-electrospray ionization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98d34db3de17de8f189579ced0013968
https://doi.org/10.1016/j.prostaglandins.2004.10.003
https://doi.org/10.1016/j.prostaglandins.2004.10.003
Publikováno v:
Current Pharmaceutical Design. 10:613-626
Our initial studies on renal cyclooxygenase (COX)-2 expression and activity addressed the critical role of angiotensin II (Ang II) in increasing tumor necrosis factor alpha (TNF) that eventuated in expression of COX-2 in the medullary thick ascending
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66728214de906a6b39a0b5b5412165c5
https://doi.org/10.2174/1381612043453063
https://doi.org/10.2174/1381612043453063
Autor:
Yu-Jung Chen, John Quilley
Publikováno v:
Hypertension. 42:837-843
In the rat isolated perfused kidney, arachidonic acid elicits cyclooxygenase-dependent vasoconstriction through activation of PGH 2 /TxA 2 receptors; responses are enhanced in kidneys from diabetic rats. This study examined the roles of cyclooxygenas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acfdd5250d10a245e39583804295f28b
https://doi.org/10.1161/01.hyp.0000085650.29823.f2
https://doi.org/10.1161/01.hyp.0000085650.29823.f2
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 304:1292-1298
Epoxyeicosatrienoic acids (EETs) are cytochrome P450-derived metabolites of arachidonic acid that elicit vasodilation via activation of K(+) channels. They have been implicated as endothelium-derived hyperpolarizing factors (EDHFs), mediating the eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78bb730360f8c04a062355392371d7ec
https://doi.org/10.1124/jpet.102.042671
https://doi.org/10.1124/jpet.102.042671