Výsledky vyhledávání - "John Markopoulos"

Akademický článek

Ruthenium-Catalyzed Selective Hydrogenation of bis-Arylidene Tetramic Acids. Application to the Synthesis of Novel Structurally Diverse Pyrrolidine-2,4-diones

Autor: Olga Igglessi-Markopoulou, John Markopoulos, Dimitris Matiadis, Christos S. Karaiskos

Publikováno v: Molecules, Vol 16, Iss 7, Pp 6116-6128 (2011)

Catalytic hydrogenation of 3,5-bis-arylidenetetramic acids, known for their biological activity, has been developed. The chemoselective ruthenium-catalyzed reduction of the exocyclic carbon-carbon double bonds on pyrrolidine-2,4-dione ring system, co

Externí odkaz: https://doaj.org/article/36662e33e0f24099becb6a26055406fa

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Akademický článek

Functionalized 4-Hydroxy Coumarins: Novel Synthesis, Crystal Structure and DFT Calculations

Autor: Olga Igglessi-Markopoulou, Vickie McKee, John Markopoulos, Valentina Stefanou, Antreas Afantitis, Giorgos Athanasellis, Georgia Melagraki, Dimitris Matiadis

Publikováno v: Molecules, Vol 16, Iss 1, Pp 384-402 (2011)

A novel short-step methodology for the synthesis in good yields of functionalized coumarins has been developed starting from an activated precursor, the N-hydroxysuccinimide ester of O-acetylsalicylic acid. The procedure is based on a tandem C-acylat

Externí odkaz: https://doaj.org/article/fe5660c050554b2dad11c59ef69490ba

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Synthesis and preliminary biological evaluation of antibacterial and antifungal 5-arylidene tetramic acid-cadmium(II) complexes

Autor: Valentina Stefanou, Dimitrios Tsironis, Dimitris Matiadis, John Markopoulos, Olga Igglessi-Markopoulou, Angeliki Panagiotopoulou

Publikováno v: Archiv der PharmazieREFERENCES. 354(12)

The synthesis and biological evaluation of 5-arylidene-N-acetyl-tetramic acids cadmium(II) complexes are reported. Eleven novel compounds were prepared, characterized by nuclear magnetic resonance experiments and screened for their antimicrobial acti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c4178c30a09b62c7b428b28c558031c
https://pubmed.ncbi.nlm.nih.gov/34570387

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A novel synthetic protocol for the synthesis of pulvinones, and naturally occurring Aspulvinone E, molecules of medicinal interest

Autor: Sotirios Katsamakas, John Markopoulos, Kyriakos C. Prousis, Olga Igglessi-Markopoulou

A novel two step methodology for readily accessible natural ��pulvinone�� derivatives in excellent yields has been developed starting from activated precursors, bearing a functionalized 1,3-dioxolane-2,4-diones (OCA��s), as duall

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::124680b743bb22beddb69eb257a7b657

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Synthesis and single crystal X-ray diffraction studies of coumarin-based Zn(II) and Mn(II) complexes, involving supramolecular interactions

Autor: Dimitrios Tsironis, Dimitrios Matiadis, Olga Igglessi-Markopoulou, Vickie McKee, Valentina Stefanou, John Markopoulos

Publikováno v: Polyhedron. 141:289-295

In this work we describe the synthesis and characterization of two supramolecular coordination complexes, namely [Zn(Cuma)2(MeOH)2] 2 and [Mn(Cuma)2(MeOH)2] 3, obtained from the self-assembly of Zn(II) and Mn(II) acceptors with the 3-benzoyl-4-hydrox

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c22c990b45c7a8e286df2122a677cf31
https://doi.org/10.1016/j.poly.2017.12.011

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Akademický článek

Coordination Behavior of 3-Ethoxycarbonyltetronic Acid towards Cu(II) and Co(II) Metal Ions

Autor: Giorgos Athanasellis, Georgia Zahariou, Stefanos Kikionis, Olga Igglessi-Markopoulou, John Markopoulos

Publikováno v: Bioinorganic Chemistry and Applications, Vol 2008 (2008)

Tetronic acids, 4-hydroxy-5H-furan-2-ones, constitute a class of heterocyclic compounds with potent biological and pharmacological activity. The β,β′-tricarbonyl moiety plays an integral role in biological systems and forms a variety of metal com

Externí odkaz: https://doaj.org/article/3ef513504ad3468294ccbe1de672bb22

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Synthesis, characterization and antimicrobial activity of N-acetyl-3-acetyl-5-benzylidene tetramic acid-metal complexes:X-ray analysis and identification of the Cd(II) complex as a potent antifungal agent

Autor: Alysha G. Elliott, Nikolaos Ioannidis, Angeliki Panagiotopoulou, John Markopoulos, Georgia Zahariou, Dimitrios Tsironis, Valentina Stefanou, Olga Igglessi-Markopoulou, Dimitris Matiadis, Vickie McKee, K. Kordatos

Publikováno v: Matiadis, D, Tsironis, D, Stefanou, V, Elliott, A G, Kordatos, K, Zahariou, G, Ioannidis, N, McKee, V, Panagiotopoulou, A, Igglessi-Markopoulou, O & Markopoulos, J 2019, ' Synthesis, characterization and antimicrobial activity of N-acetyl-3-acetyl-5-benzylidene tetramic acid-metal complexes : X-ray analysis and identification of the Cd(II) complex as a potent antifungal agent ', Journal of Inorganic Biochemistry, vol. 194, no. May, pp. 65-73 . https://doi.org/10.1016/j.jinorgbio.2019.02.008

This study aims at the further expansion of knowledge on the antimicrobial activities of the tetramic acid moiety and the effect of metal complexation. Complexes of the N-acetyl-3-acetyl-5-benzylidenetetramic acid with Mn, Co, Ni, Cu, Zn and Cd were

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84882b81d30ae036b94ac0302e1daf6f
https://findresearcher.sdu.dk:8443/ws/files/153658579/Synthesis_characterization_and_antimicrobial_activity_of_N_acetyl_3_acetyl_5_benzylidene_tetramic_acid_metal.pdf

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Synthesis, biological evaluation and structure-activity relationships of 5-arylidene tetramic acids with antibacterial activity against methicillin-resistant Staphylococcus aureus

Autor: Dimitrios Tsironis, Angeliki Panagiotopoulou, John Markopoulos, Vickie McKee, Spyridon Boussias, Olga Igglessi-Markopoulou, Valentina Stefanou, Dimitris Matiadis

Publikováno v: Matiadis, D, Tsironis, D, Stefanou, V, Boussias, S, Panagiotopoulou, A, McKee, V, Igglessi-Markopoulou, O & Markopoulos, J 2020, ' Synthesis, biological evaluation and structure-activity relationships of 5-arylidene tetramic acids with antibacterial activity against methicillin-resistant Staphylococcus aureus ', Bioorganic and Medicinal Chemistry Letters, vol. 30, no. 10, 127107 . https://doi.org/10.1016/j.bmcl.2020.127107

The steady rise of the antimicrobial resistance is a major global threat to human health that requires the urgent need for novel antibiotics. In this work we report the synthesis of a small library of 3-subsituted-5-arylidene tetramic acids in order

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70debac5f09ca9d7a6dc68e00e1e5884
https://doi.org/10.1016/j.bmcl.2020.127107

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