Myostatin and activin blockade by engineered follistatin results in hypertrophy and improves dystrophic pathology in mdx mouse more than myostatin blockade alone

Autor: Andrea Iskenderian, Nan Liu, Qingwei Deng, Yan Huang, Chuan Shen, Kathleen Palmieri, Robert Crooker, Dianna Lundberg, Niksa Kastrapeli, Brian Pescatore, Alla Romashko, John Dumas, Robert Comeau, Angela Norton, Jing Pan, Haojing Rong, Katayoun Derakhchan, David E. Ehmann

Publikováno v: Skeletal Muscle, Vol 8, Iss 1, Pp 1-16 (2018)

Abstract Background Myostatin antagonists are being developed as therapies for Duchenne muscular dystrophy due to their strong hypertrophic effects on skeletal muscle. Engineered follistatin has the potential to combine the hypertrophy of myostatin a

Externí odkaz: https://doaj.org/article/67bfaa2651914f7787073ccc6974c8c1

The Sundowner Winds Experiment (SWEX) Pilot Study: Understanding Downslope Windstorms in the Santa Ynez Mountains, Santa Barbara, California

Autor: Dave Gomberg, Charles Jones, Woody Enos, B. Gamelin, Rob Hazard, Gert-Jan Duine, Katelyn Zigner, Todd Hall, Garret Bell, Leila M. V. Carvalho, Craig B. Clements, John Dumas, Mark Jackson, Heather Kane, Chloe Gore, Eric Boldt

Publikováno v: MONTHLY WEATHER REVIEW, vol 148, iss 4

Sundowner winds are downslope gusty winds often observed on the southern slopes of the Santa Ynez Mountains (SYM) in coastal Santa Barbara (SB), California. They typically peak near sunset and exhibit characteristics of downslope windstorms through t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9b4e41d100055e6076367ac74f63432
https://doi.org/10.1175/mwr-d-19-0207.1

Power Generation Frequency Response

Autor: Ravikanth Varanasi, Pradeep Tripathi, Bracy Nesbit, John Dumas

Publikováno v: 2020 IEEE Texas Power and Energy Conference (TPEC).

Power generation equipment response to large frequency deviations has been modeled since the origination of interconnected power systems. The application of more advanced models in power system stability allows system operators and planners to determ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::37266dc81b320c7b3b079a2a3ac45130
https://doi.org/10.1109/tpec48276.2020.9042499

Myostatin and activin blockade by engineered follistatin results in hypertrophy and improves dystrophic pathology in mdx mouse more than myostatin blockade alone

Autor: Jing Pan, Alla Romashko, David E. Ehmann, Katayoun Derakhchan, Angela W. Norton, Andrea Iskenderian, Qingwei Deng, Robert Comeau, Robert Crooker, Nan Liu, John Dumas, Chuan Shen, Niksa Kastrapeli, Dianna Lundberg, Brian Pescatore, Kathleen Palmieri, Haojing Rong, Yan Huang

Publikováno v: Skeletal Muscle
Skeletal Muscle, Vol 8, Iss 1, Pp 1-16 (2018)

Background Myostatin antagonists are being developed as therapies for Duchenne muscular dystrophy due to their strong hypertrophic effects on skeletal muscle. Engineered follistatin has the potential to combine the hypertrophy of myostatin antagonism

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae2104cea901b16f8803bff66aa10bb0
https://pubmed.ncbi.nlm.nih.gov/30368252

WRF simulation of downslope wind events in coastal Santa Barbara County

Autor: Mark Jackson, Forest Cannon, Todd Hall, Charles Jones, Leila M. V. Carvalho, David Gomberg, John Dumas

Publikováno v: Cannon, F; Carvalho, LMV; Jones, C; Hall, T; Gomberg, D; Dumas, J; et al.(2017). WRF simulation of downslope wind events in coastal Santa Barbara County. ATMOSPHERIC RESEARCH, 191, 57-73. doi: 10.1016/j.atmosres.2017.03.010. UC Santa Barbara: Retrieved from: http://www.escholarship.org/uc/item/8h89t6zv
ATMOSPHERIC RESEARCH, vol 191

The National Weather Service (NWS) considers frequent gusty downslope winds, accompanied by rapid warming and decreased relative humidity, among the most significant weather events affecting southern California coastal areas in the vicinity of Santa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1abfef5f1b99a4d0e5e1cc82b046574d
https://escholarship.org/uc/item/8h89t6zv