Zobrazeno 1 - 10
of 377
pro vyhledávání: '"John, van der Oost"'
Autor:
Despoina Trasanidou, Ana Potocnik, Patrick Barendse, Prarthana Mohanraju, Evgenios Bouzetos, Efthymios Karpouzis, Amber Desmet, Richard van Kranenburg, John van der Oost, Raymond H. J. Staals, Ioannis Mougiakos
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
Abstract Anti-CRISPR proteins (Acrs) block the activity of CRISPR-associated (Cas) proteins, either by inhibiting DNA interference or by preventing crRNA loading and complex formation. Although the main use of Acrs in genome engineering applications
Externí odkaz:
https://doaj.org/article/f440bd2a17af489fb61d09f20fca172a
Autor:
Constantinos Patinios, Stijn T. de Vries, Mamou Diallo, Lucrezia Lanza, Pepijn L. J. V. Q. Verbrugge, Ana M. López-Contreras, John van der Oost, Ruud A. Weusthuis, Servé W. M. Kengen
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Clostridium species are re-emerging as biotechnological workhorses for industrial acetone–butanol–ethanol production. This re-emergence is largely due to advances in fermentation technologies but also due to advances in genome engineerin
Externí odkaz:
https://doaj.org/article/ec99f4154282427390a6e1d961b087f8
Autor:
James C. Dykstra, Jelle van Oort, Ali Tafazoli Yazdi, Eric Vossen, Constantinos Patinios, John van der Oost, Diana Z. Sousa, Servé W. M. Kengen
Publikováno v:
Microbial Cell Factories, Vol 21, Iss 1, Pp 1-11 (2022)
Abstract Background Ethyl acetate is a bulk chemical traditionally produced via energy intensive chemical esterification. Microbial production of this compound offers promise as a more sustainable alternative process. So far, efforts have focused on
Externí odkaz:
https://doaj.org/article/dd7f01b57af948f59b517e068abbe117
Autor:
Jurre A. Steens, Yifan Zhu, David W. Taylor, Jack P. K. Bravo, Stijn H. P. Prinsen, Cor D. Schoen, Bart J. F. Keijser, Michel Ossendrijver, L. Marije Hofstra, Stan J. J. Brouns, Akeo Shinkai, John van der Oost, Raymond H. J. Staals
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Type III CRISPR-Cas systems recognize and cleave target RNAs and produce signalling molecules. Here the authors discover that both processes are governed by a flexible seed region, ultimately resulting in SCOPE, a SARSCoV-2 diagnostic assay with atto
Externí odkaz:
https://doaj.org/article/e3174dc9798f445a945c96d9e82fdcc7
Autor:
Lorenzo Olivi, Mareike Berger, Ramon N. P. Creyghton, Nicola De Franceschi, Cees Dekker, Bela M. Mulder, Nico J. Claassens, Pieter Rein ten Wolde, John van der Oost
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
A key feature of living cells is the cell cycle. In this Perspective, the authors explore attempts to recreate this process and what is still required for an integrated synthetic cell cycle.
Externí odkaz:
https://doaj.org/article/204d76b9054b4a2f8e986d1428941935
Autor:
Catarina Loureiro, Anastasia Galani, Asimenia Gavriilidou, Maryam Chaib de Mares, John van der Oost, Marnix H. Medema, Detmer Sipkema
Publikováno v:
mSystems, Vol 7, Iss 4 (2022)
ABSTRACT Marine sponges and their microbial symbiotic communities are rich sources of diverse natural products (NPs) that often display biological activity, yet little is known about the global distribution of NPs and the symbionts that produce them.
Externí odkaz:
https://doaj.org/article/45c102bcb1f64a5b9140e67449ee7afe
Autor:
Enrico Orsi, Ioannis Mougiakos, Wilbert Post, Jules Beekwilder, Marco Dompè, Gerrit Eggink, John van der Oost, Servé W. M. Kengen, Ruud A. Weusthuis
Publikováno v:
Biotechnology for Biofuels, Vol 13, Iss 1, Pp 1-13 (2020)
Abstract Background Microbial cell factories are usually engineered and employed for cultivations that combine product synthesis with growth. Such a strategy inevitably invests part of the substrate pool towards the generation of biomass and cellular
Externí odkaz:
https://doaj.org/article/662cd64da79e4bc3890e71c1e81dc9a4
Autor:
Aleksander J. Kruis, Anna C. Bohnenkamp, Bram Nap, Jochem Nielsen, Astrid E. Mars, Rene H. Wijffels, John van der Oost, Servé W. M. Kengen, Ruud A. Weusthuis
Publikováno v:
Biotechnology for Biofuels, Vol 13, Iss 1, Pp 1-10 (2020)
Abstract Background Genetic engineering of microorganisms has become a common practice to establish microbial cell factories for a wide range of compounds. Ethyl acetate is an industrial solvent that is used in several applications, mainly as a biode
Externí odkaz:
https://doaj.org/article/e0745272469f421f9292af30cddc3360
Autor:
Anna C. Bohnenkamp, Aleksander J. Kruis, Astrid E. Mars, Rene H. Wijffels, John van der Oost, Servé W. M. Kengen, Ruud A. Weusthuis
Publikováno v:
Biotechnology for Biofuels, Vol 13, Iss 1, Pp 1-14 (2020)
Abstract Background Ethyl acetate is a widely used industrial solvent that is currently produced by chemical conversions from fossil resources. Several yeast species are able to convert sugars to ethyl acetate under aerobic conditions. However, perfo
Externí odkaz:
https://doaj.org/article/5f710161147d4de98e2c28520e484738
Autor:
Giovanni Gallo, Ioannis Mougiakos, Mauricio Bianco, Miriam Carbonaro, Andrea Carpentieri, Anna Illiano, Pietro Pucci, Simonetta Bartolucci, John van der Oost, Gabriella Fiorentino
Publikováno v:
mBio, Vol 12, Iss 6 (2021)
ABSTRACT Arsenic detoxification systems can be found in a wide range of organisms, from bacteria to humans. In a previous study, we discovered an arsenic-responsive transcriptional regulator in the thermophilic bacterium Thermus thermophilus HB27 (Tt
Externí odkaz:
https://doaj.org/article/6e7a5ba0739a4318872baf2b1905d939