Zobrazeno 1 - 10
of 76
pro vyhledávání: '"John, Whittle"'
Autor:
Jeroen Molinger, John Whittle, Henrik Endeman, David MacLeod, Rajan Gupta, Marat Fudim, Krista L. Haines, Christina Barkauskas, Zachary Healy, Paul Wischmeyer, Jan Bakker
Publikováno v:
Frontiers in Anesthesiology, Vol 3 (2024)
BackgroundMuscle wasting is a common finding in critically ill patients associated with increased days of mechanical ventilation in the ICU. Muscle wasting and associated morphological changes are hallmarks of ICU-acquired weakness. Muscle wasting ca
Externí odkaz:
https://doaj.org/article/07396a54023c4250bf13e957a840efce
Autor:
Jeroen Molinger, John Whittle, Susie Cha, David MacLeod, Marat Fudim, Luis Ulloa, Christina Barkauskas, Zachary Healy, Krista L. Haines, Rajan T. Gupta, Henrik Endeman, Mathieu van der Jagt, Diederik Gommers, Jan Bakker, Paul E. Wischmeyer
Publikováno v:
Frontiers in Anesthesiology, Vol 3 (2024)
IntroductionThe COVID-19 pandemic brought unprecedented challenges to healthcare systems worldwide, particularly the often challenging physical recovery from critical illness. Among the myriad complications faced by these patients, ICU-acquired weakn
Externí odkaz:
https://doaj.org/article/c1678bfd796f45509c3428e33d0f7e17
Early dynamic changes to monocytes following major surgery are associated with subsequent infections
Autor:
Timothy Arthur Chandos Snow, Alessia V. Waller, Richard Loye, Francis Ryckaert, Antonio Cesar, Naveed Saleem, Rudra Roy, John Whittle, Ahmed Al-Hindawi, Abhishek Das, Mervyn Singer, David Brealey, Nishkantha Arulkumaran, the University College London Hospitals Critical Care Research Team
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundPost-operative infections are a common cause of morbidity following major surgery. Little is understood about how major surgery perturbs immune function leading to heightened risk of subsequent infection. Through analysis of paired blood sa
Externí odkaz:
https://doaj.org/article/d75a2c2b5da44cf9bd0a7ca3a48d373e
Autor:
Nicholas Tetlow, Amy Dewar, Pietro Arina, Melanie Tan, Ashwin N. Sridhar, John D. Kelly, Nishkantha Arulkumaran, Robert C.M. Stephens, Daniel S. Martin, Suneetha R. Moonesinghe, John Whittle
Publikováno v:
BJA Open, Vol 9, Iss , Pp 100255- (2024)
Background: Lower fitness is a predictor of adverse outcomes after radical cystectomy. Lockdown measures during the COVID-19 pandemic affected daily physical activity. We hypothesised that lockdown during the pandemic was associated with a reduction
Externí odkaz:
https://doaj.org/article/60477c384c6e43b6a903a0ab8cd1764c
Autor:
Michael W. Manning, John Whittle, Matthew Fuller, Sara H. Cooper, Erin L. Manning, Joe Chapman, Judd W. Moul, Timothy E. Miller
Publikováno v:
Perioperative Medicine, Vol 12, Iss 1, Pp 1-10 (2023)
Abstract Background Opioid use has come under increasing scrutiny, driven in part by the opioid crisis and growing concerns that up to 6% of opioid-naïve patients may become chronic opioid users. This has resulted in a revaluation of perioperative p
Externí odkaz:
https://doaj.org/article/20e108a4873240168f1094ec8f60c722
Autor:
Robert Tracey, Vadim Elisseev, Michalis Smyrnakis, Lan Hoang, Mark Fellows, Michael Ackers, Andrew Laughton, Stephen Hill, Phillip Folkes, John Whittle
Publikováno v:
Applied AI Letters, Vol 4, Iss 4, Pp n/a-n/a (2023)
Abstract We present bespoke energy efficiency optimizations in high performance computing (HPC) environments using holistic approach to data collection, analysis and proactive management of resources and workloads. Our solution has three major compon
Externí odkaz:
https://doaj.org/article/48e41d27bc884d10b78b5d751a3bba83
Autor:
John Whittle, Jeroen Molinger, David MacLeod, Krista Haines, Paul E. Wischmeyer, for the LEEP-COVID Study Group
Publikováno v:
Critical Care, Vol 24, Iss 1, Pp 1-4 (2020)
Externí odkaz:
https://doaj.org/article/9be9f4f330024428b398cb0a056324c0
Autor:
Greg S. Martin, David A. Kaufman, Paul E. Marik, Nathan I. Shapiro, Denny Z. H. Levett, John Whittle, David B. MacLeod, Desiree Chappell, Jonathan Lacey, Tom Woodcock, Kay Mitchell, Manu L. N. G. Malbrain, Tom M. Woodcock, Daniel Martin, Chris H. E. Imray, Michael W. Manning, Henry Howe, Michael P. W. Grocott, Monty G. Mythen, Tong J. Gan, Timothy E. Miller
Publikováno v:
Perioperative Medicine, Vol 9, Iss 1, Pp 1-12 (2020)
Abstract Background Optimal fluid therapy in the perioperative and critical care settings depends on understanding the underlying cardiovascular physiology and individualizing assessment of the dynamic patient state. Methods The Perioperative Quality
Externí odkaz:
https://doaj.org/article/05b8a6c2162e4e63acba9662dadc823b
Autor:
Heung-Yan Wong, Lorna Starsmore, Nicholas Tetlow, Amy Dewar, Olivia Chapman, Jessica Lipman, James Pidding, Kassie Montanheiro, Uta Bellin, John Whittle
Publikováno v:
BJA Open, Vol 4, Iss , Pp 100069- (2022)
Externí odkaz:
https://doaj.org/article/63c6761c42bf4915acbad0a6feb8872c
Focused cardiac ultrasound in preoperative assessment: the perioperative provider’s new stethoscope?
Publikováno v:
Perioperative Medicine, Vol 8, Iss 1, Pp 1-8 (2019)
Abstract Focused cardiac ultrasound (FoCUS)—a simplified, qualitative version of echocardiography—is a well-established tool in the armamentarium of critical care and emergency medicine. This review explores the extent to which FoCUS could also b
Externí odkaz:
https://doaj.org/article/af3f1837be1b467c8b18b0c1a4437b3a