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Detection and localization of early- and late-stage cancers using platelet RNA

Autor: In ’t Veld, Sjors G.J.G. ^{1, 2, 3, 4, 5}, Arkani, Mohammad ^{1, 2, 3, 6, 68}, Post, Edward ^{1, 2, 3, 68}, Antunes-Ferreira, Mafalda ^{1, 2, 3, 68}, D’Ambrosi, Silvia ^{1, 2, 3, 68}, Vessies, Daan C.L. ⁷, Vermunt, Lisa ^{4, 5}, Vancura, Adrienne ^{1, 2, 3}, Muller, Mirte ⁸, Niemeijer, Anna-Larissa N. ⁶, Tannous, Jihane ^{9, 10}, Meijer, Laura L. ^{2, 11}, Le Large, Tessa Y.S. ^{2, 11}, Mantini, Giulia ^{2, 12}, Wondergem, Niels E. ^{2, 13}, Heinhuis, Kimberley M. ^{14, 15}, van Wilpe, Sandra ¹⁶, Smits, A. Josien ⁶, Drees, Esther E.E. ^{2, 17}, Roos, Eva ¹¹, Leurs, Cyra E. ^{5, 18, 19}, Tjon Kon Fat, Lee-Ann ²⁰, van der Lelij, Ewoud J. ^{1, 2, 3}, Dwarshuis, Govert ^{1, 2, 3}, Kamphuis, Maarten J. ^{1, 2, 3}, Visser, Lisanne E. ^{1, 2, 3}, Harting, Romee ^{1, 2, 3}, Gregory, Annemijn ^{1, 2, 3}, Schweiger, Markus W. ^{1, 2, 3, 9, 10}, Wedekind, Laurine E. ^{1, 2, 3}, Ramaker, Jip ^{1, 2, 3}, Zwaan, Kenn ^{1, 2, 3}, Verschueren, Heleen ^{1, 2, 3}, Bahce, Idris ⁶, de Langen, Adrianus J. ⁸, Smit, Egbert F. ⁸, van den Heuvel, Michel M. ^{8, 21}, Hartemink, Koen J. ²², Kuijpers, Marijke J.E. ^{23, 24}, oude Egbrink, Mirjam G.A. ²⁵, Griffioen, Arjan W. ^{2, 12}, Rossel, Rafael ^{26, 27, 28, 29}, Hiltermann, T. Jeroen N. ³⁰, Lee-Lewandrowski, Elizabeth ³¹, Lewandrowski, Kent B. ³¹, De Witt Hamer, Philip C. ^{1, 2, 3}, Kouwenhoven, Mathilde ^{2, 3, 18}, Reijneveld, Jaap C. ^{2, 3, 18, 32}, Leenders, William P.J. ³³, Hoeben, Ann ³⁴, Verdonck-de Leeuw, Irma M. ^{2, 13, 35}, Leemans, C. René ¹³, Baatenburg de Jong, Robert J. ³⁶, Terhaard, Chris H.J. ³⁷, Takes, Robert P. ³⁸, Langendijk, Johannes A. ³⁹, de Jager, Saskia C. ⁴⁰, Kraaijeveld, Adriaan O. ⁴¹, Pasterkamp, Gerard ⁴⁰, Smits, Minke ¹⁶, Schalken, Jack A. ^{42, 43}, Łapińska-Szumczyk, Sylwia ⁴⁴, Łojkowska, Anna ⁴⁴, Żaczek, Anna J. ⁴⁵, Lokhorst, Henk ^{2, 46}, van de Donk, Niels W.C.J. ^{2, 46}, Nijhof, Inger ^{2, 46}, Prins, Henk-Jan ^{2, 46}, Zijlstra, Josée M. ^{2, 46}, Idema, Sander ^{1, 2, 3}, Baayen, Johannes C. ^{1, 2, 3}, Teunissen, Charlotte E. ^{4, 5}, Killestein, Joep ^{5, 18, 19}, Besselink, Marc G. ¹¹, Brammen, Lindsay ⁴⁷, Bachleitner-Hofmann, Thomas ⁴⁸, Mateen, Farrah ⁹, Plukker, John T.M. ⁴⁹, Heger, Michal ^{50, 51}, de Mast, Quirijn ⁵², Lisman, Ton ^{49, 53}, Pegtel, D. Michiel ^{2, 17}, Bogaard, Harm-Jan ⁶, Jassem, Jacek ⁵⁴, Supernat, Anna ⁴⁵, Mehra, Niven ¹⁶, Gerritsen, Winald ¹⁶, de Kroon, Cornelis D. ⁵⁵, Lok, Christianne A.R. ^{56, 57}, Piek, Jurgen M.J. ⁵⁸, Steeghs, Neeltje ^{14, 15}, van Houdt, Winan J. ⁵⁹, Brakenhoff, Ruud H. ^{2, 13}, Sonke, Gabe S. ¹⁴, Verheul, Henk M. ¹⁶, Giovannetti, Elisa ^{2, 12, 60}, Kazemier, Geert ^{2, 11}, Sabrkhany, Siamack ⁶¹, Schuuring, Ed ⁶², Sistermans, Erik A. ^{63, 64}, Wolthuis, Rob ⁶³, Meijers-Heijboer, Hanne ⁶³, Dorsman, Josephine ⁶³, Oudejans, Cees ⁶⁵, Ylstra, Bauke ^{2, 17}, Westerman, Bart A. ^{1, 2, 3}, van den Broek, Daan ⁷, Koppers-Lalic, Danijela ^{1, 2, 3}, Wesseling, Pieter ^{2, 3, 17, 66}, Nilsson, R. Jonas A. ²⁰, Vandertop, W. Peter ^{1, 2, 3}, Noske, David P. ^{1, 2, 3}, Tannous, Bakhos A. ^{9, 10}, Sol, Nik ^{2, 3, 18}, Best, Myron G. ^{1, 2, 3, 67, ∗}, Wurdinger, Thomas ^{1, 2, 3, 67, 69, ∗∗}

Publikováno v: In Cancer Cell 12 September 2022 40(9):999-1009

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Reaction Dynamics in the Chrimson Channelrhodopsin: Observation of Product-State Evolution and Slow Diffusive Protein Motions

Autor: Ivo H.M. van Stokkum, Yusaku Hontani, Johannes Vierock, Benjamin S. Krause, Peter Hegemann, John T.M. Kennis

Publikováno v: van Stokkum, I H M, Hontani, Y, Vierock, J, Krause, B S, Hegemann, P & Kennis, J T M 2023, ' Reaction Dynamics in the Chrimson Channelrhodopsin : Observation of Product-State Evolution and Slow Diffusive Protein Motions ', Journal of Physical Chemistry Letters, vol. 14, no. 6, pp. 1485-1493 . https://doi.org/10.1021/acs.jpclett.2c03110
Journal of Physical Chemistry Letters, 14(6), 1485-1493. American Chemical Society

Chrimson is a red-light absorbing channelrhodopsin useful for deep-tissue optogenetics applications. Here, we present the Chrimson reaction dynamics from femtoseconds to seconds, analyzed with target analysis methods to disentangle spectrally and tem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59efdf7779fbe6fc97a78a96925d9b8c
https://doi.org/10.1021/acs.jpclett.2c03110

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