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pro vyhledávání: '"John, Sundy"'
Autor:
Jyothsna Visweswaraiah, Erik R Sampson, Timothy Kiprono, Parika Petaipimol, Adrianne Monsef, Katalin Kis-Toth, Kevin L Otipoby, John Sundy, Nathan Higginson-Scott, Joanne L Viney
Publikováno v:
The Journal of Immunology. 206:66.14-66.14
Regulatory T cells (Treg) are vital for immune homeostasis and are dysfunctional in autoimmunity. Interleukin 2 (IL-2) drives the proliferation and function of Tregs via its heterotrimeric receptor (CD25/CD122/CD132). Low dose IL-2 is being evaluated
Publikováno v:
Arthritis careresearch. 66(1)
Tophi are strongly associated with structural damage in gout, and urate-lowering therapy reduces tophus size. Pegloticase leads to dramatic reductions in serum urate and subcutaneous tophi in treatment responders. The aim of this analysis was to exam