Zobrazeno 1 - 10
of 239
pro vyhledávání: '"John, Staffurth"'
Autor:
Philip A Wheeler, Nicholas S West, Richard Powis, Rhydian Maggs, Michael Chu, Rachel A Pearson, Nick Willis, Bartlomiej Kurec, Katie L. Reed, David G. Lewis, John Staffurth, Emiliano Spezi, Anthony E. Millin
Publikováno v:
Radiation Oncology, Vol 19, Iss 1, Pp 1-11 (2024)
Abstract Background Current automated planning solutions are calibrated using trial and error or machine learning on historical datasets. Neither method allows for the intuitive exploration of differing trade-off options during calibration, which may
Externí odkaz:
https://doaj.org/article/e896d6b30ee2484b927251cdf6a63ef2
Autor:
Julia Murray, Clare Cruickshank, Thomas Bird, Philip Bell, John Braun, Dave Chuter, Miguel Reis Ferreira, Clare Griffin, Shama Hassan, Nabil Hujairi, Alan Melcher, Elizabeth Miles, Olivia Naismith, Miguel Panades, Lara Philipps, Alison Reid, Jan Rekowski, Pete Sankey, John Staffurth, Isabel Syndikus, Alison Tree, Anna Wilkins, Emma Hall
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 37, Iss , Pp 130-136 (2022)
PEARLS is a multi-stage randomised controlled trial for prostate cancer patients with pelvic and/or para-aortic PSMA-avid lymph node disease at presentation. The aim of the trial is to determine whether extending the radiotherapy field to cover the p
Externí odkaz:
https://doaj.org/article/9d5bb06b8f354a2eb2ed28ed2d5a83c2
Autor:
Rebecca Maier, Aislinn Cooper, Robert Chandler, John Marshall, Simon Crabb, Amit Bahl, Ian Pedley, Suneil Jain, John Staffurth, Rob Jones, Rakesh Heer, Paul Gravestock, Miranda Morton, Emma Clark, Holly Fisher, Shirya Sharma, Ruth Wood, Jenn Walker, Nichola Waugh, Helen Hancock
Publikováno v:
NIHR Open Research, Vol 2 (2023)
Background: Prostate cancer is the most commonly diagnosed malignancy in the UK. Castrate resistant prostate cancer (CRPC) can be difficult to manage with response to next generation hormonal treatment variable. AR-V7 is a protein biomarker that can
Externí odkaz:
https://doaj.org/article/3d23599209254e9d8aff6029a8adb3e8
Autor:
Emily Day, A. Toby Prevost, Matthew R. Sydes, Deepika Reddy, Taimur T. Shah, Mathias Winkler, Tim Dudderidge, John Staffurth, Stuart McCracken, Vincent Khoo, Puja Jadav, Natalia Klimowska-Nassar, Thiagarajah Sasikaran, Hashim U. Ahmed, Francesca Fiorentino
Publikováno v:
Trials, Vol 22, Iss 1, Pp 1-12 (2021)
Abstract Background Randomised controlled trials (RCTs) for surgical interventions have often proven difficult with calls for innovative approaches. The Imperial Prostate (IP4) Comparative Health Research Outcomes of Novel Surgery in prostate cancer
Externí odkaz:
https://doaj.org/article/852ed8f3f23e4607b9359eacd6bd00ac
Autor:
Isabel Syndikus, Clare Cruickshank, John Staffurth, Alison Tree, Ann Henry, Olivia Naismith, Helen Mayles, Nicola Snelson, Shama Hassan, Stephanie Brown, Nuria Porta, Clare Griffin, Emma Hall
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 25, Iss , Pp 22-28 (2020)
Externí odkaz:
https://doaj.org/article/c81d91f1001c400988d3a8c3ab087d8c
Autor:
Julia Murray, Sarah Gulliford, Clare Griffin, Anna Wilkins, Isabel Syndikus, John Staffurth, Miguel Panades, Christopher Scrase, Chris Parker, Vincent Khoo, Jamie Dean, Helen Mayles, Philip Mayles, Simon Thomas, Olivia Naismith, Helen Mossop, Clare Cruickshank, Emma Hall, David Dearnaley
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 21, Iss , Pp 77-84 (2020)
Background and purpose: The penile bulb (PB) dose may be critical in development of post prostate radiotherapy erectile dysfunction (ED). This study aimed to generate PB dose constraints based on dose-volume histograms (DVHs) in patients treated with
Externí odkaz:
https://doaj.org/article/75d46294698e45fea603c53689843625
Publikováno v:
Radiation Oncology, Vol 14, Iss 1, Pp 1-14 (2019)
Abstract Background Advanced pelvic radiotherapy techniques aim to reduce late bowel toxicity which can severely impact the lives of pelvic cancer survivors. Although advanced techniques have been largely adopted worldwide, to achieve their aim, know
Externí odkaz:
https://doaj.org/article/cdacc6c7aff243ed9cc7e7f5fa1f9069
Autor:
Philip A. Wheeler, Michael Chu, Rosemary Holmes, Maeve Smyth, Rhydian Maggs, Emiliano Spezi, John Staffurth, David G. Lewis, Anthony E. Millin
Publikováno v:
Physics and Imaging in Radiation Oncology, Vol 10, Iss , Pp 41-48 (2019)
Background and purpose: Current automated radiotherapy planning solutions do not allow for the intuitive exploration of different treatment options during protocol calibration. This work introduces an automated planning solution, which aims to addres
Externí odkaz:
https://doaj.org/article/aa1b5ee9d920485594d5ef4a3f60d6d3
Autor:
Christopher J Sweeney, Andrew J Martin, Martin R Stockler, Stephen Begbie, Leanna Cheung, Kim N Chi, Simon Chowdhury, Mark Frydenberg, Lisa G Horvath, Anthony M Joshua, Nicola J Lawrence, Gavin Marx, John McCaffrey, Ray McDermott, Margaret McJannett, Scott A North, Francis Parnis, Wendy Parulekar, David W Pook, Martin Neil Reaume, Shahneen K Sandhu, Alvin Tan, Thean Hsiang Tan, Alastair Thomson, Francisco Vera-Badillo, Scott G Williams, Diana Winter, Sonia Yip, Alison Y Zhang, Robert R Zielinski, Ian D Davis, Ehtesham Abdi, Suzanne Allan, Patricia Bastick, Robert Blum, Karen Briscoe, Daniel Brungs, Sean Bydder, Bala Renuka Chittajallu, Michelle Cronk, Katharine Cuff, Anthony Dowling, Matthew George, Lisa Horvath, Elizabeth Hovey, Anthony Joshua, Narayan Karanth, Ganessan Kichenadasse, Laurence Krieger, Maitham Mathlum, Louise Nott, Zulfiquer Otty, David Pook, Shahneen Sandhu, Sanjeev Sewak, Amanda Stevanovic, Martin Stockler, Aneta Suder, Hsiang Tan, Javier Torres, Simon Troon, Craig Underhill, Andrew Weickhardt, Robert Zielinski, Tahir Abbas, Ghadeer Anan, Chris Booth, Holly Campbell, Kim Chi, Joseph Chin, Edmond Chouinard, Bryan Donnelly, Darrel Drachenberg, Amir Faghih, Antonio Finelli, Sebastien Hotte, Krista Noonan, Scott North, Mohammad Rassouli, Neil Reaume, Ricardo Rendon, Fred Saad, Evgeny Sadikov, Eric Vigneault, Pawel Zalewski, Patrick Morris, Miriam O'Connor, Paul Donnellan, Dearbhaile O'Donnell, Jim Edwards, Peter Fong, Simon Crabb, Omar Khan, Vincent Khoo, Graham Macdonald, Heather Payne, Angus Robinson, Jonathon Shamash, John Staffurth, Carys Thomas
Publikováno v:
The Lancet Oncology. 24:323-334
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3cc53ef2d430b7a9cb81427e074aeef
https://doi.org/10.1016/s1470-2045(23)00063-3
https://doi.org/10.1016/s1470-2045(23)00063-3
Autor:
Douglas Adamson, Jane Blazeby, Catharine Porter, Christopher Hurt, Gareth Griffiths, Annmarie Nelson, Bernadette Sewell, Mari Jones, Martina Svobodova, Deborah Fitzsimmons, Lisette Nixon, Jim Fitzgibbon, Stephen Thomas, Anthony Millin, Tom Crosby, John Staffurth, Anthony Byrne
Publikováno v:
Health Technology Assessment, Vol 25, Iss 31 (2021)
Background: Most patients with oesophageal cancer present with incurable disease. For those with advanced disease, the mean survival is 3–5 months. Treatment emphasis is therefore on effective palliation, with the majority of patients requiring int
Externí odkaz:
https://doaj.org/article/e9af995b9a6642c687a23a2446f6c8f4