Zobrazeno 1 - 10
of 194
pro vyhledávání: '"John, Souglakos"'
Autor:
Eleftherios Trivizakis, Nikoletta-Maria Koutroumpa, John Souglakos, Apostolos Karantanas, Michalis Zervakis, Kostas Marias
Publikováno v:
BioMedical Engineering OnLine, Vol 22, Iss 1, Pp 1-18 (2023)
Abstract Background Multi-omics research has the potential to holistically capture intra-tumor variability, thereby improving therapeutic decisions by incorporating the key principles of precision medicine. The purpose of this study is to identify a
Externí odkaz:
https://doaj.org/article/542e4cc7c8e9449ca8407bffbbdc35bd
Autor:
Dimitrios K. Manatakis, Maria Tzardi, John Souglakos, John Tsiaoussis, Christos Agalianos, Ioannis D. Kyriazanos, George Pechlivanides, Athanasios Kordelas, Nikolaos Tasis, Nikolaos Gouvas, Evaghelos Xynos
Publikováno v:
Current Oncology, Vol 30, Iss 3, Pp 2879-2888 (2023)
Background: Colon cancer surgery is a complex clinical pathway and traditional quality metrics may exhibit significant variability between hospitals and healthcare providers. The Textbook Outcome (TO) is a composite quality marker capturing the fract
Externí odkaz:
https://doaj.org/article/dfb2389469d54b24b93d42e453aadef3
Autor:
Taxiarchis Konstantinos Nikolouzakis, Elena Vakonaki, Polychronis D. Stivaktakis, Athanasios Alegakis, Aikaterini Berdiaki, Nikolaos Razos, John Souglakos, Aristidis Tsatsakis, John Tsiaoussis
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
PurposeDue to the current practice on colorectal cancer (CRC) management, chemoresistance is most often recognized at the end of the treatment. Therefore, effective and easy-to-use prognostic biomarkers are needed.Experimental DesignWe evaluated the
Externí odkaz:
https://doaj.org/article/b67de34f6bf244b1bc1ca787ede73ad9
Autor:
Jun Yin, Shaheenah Dawood, Romain Cohen, Jeff Meyers, John Zalcberg, Takayuki Yoshino, Matthew Seymour, Tim Maughan, Leonard Saltz, Eric Van Cutsem, Alan Venook, Hans-Joachim Schmoll, Richard Goldberg, Paulo Hoff, J. Randolph Hecht, Herbert Hurwitz, Cornelis Punt, Eduard Diaz Rubio, Miriam Koopman, Chiara Cremolini, Volker Heinemann, Christophe Tournigard, Carsten Bokemeyer, Charles Fuchs, Niall Tebbutt, John Souglakos, Jean-Yves Doulliard, Fairooz Kabbinavar, Benoist Chibaudel, Aimery de Gramont, Qian Shi, Axel Grothey, Richard Adams
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 13 (2021)
Background: Benchmarking international cancer survival differences is necessary to evaluate and improve healthcare systems. Our aim was to assess the potential regional differences in outcomes among patients with metastatic colorectal cancer (mCRC) p
Externí odkaz:
https://doaj.org/article/bf4aa20a3f6a47ca83257f0396cc016f
Publikováno v:
Diagnostics, Vol 11, Iss 12, p 2383 (2021)
Radiogenomic and radiotranscriptomic studies have the potential to pave the way for a holistic decision support system built on genomics, transcriptomics, radiomics, deep features and clinical parameters to assess treatment evaluation and care planni
Externí odkaz:
https://doaj.org/article/010ad89143bf44279ef1dd7b72a26eaf
Autor:
John Souglakos, Vassilis Georgoulias, Dimitris Mavroudis, Dora Hatzidaki, Maria Perraki, Ioannis Koutroubakis, Stella Apostolaki, Zacharenia Saridaki, Maria Sfakianaki, Georgios Agoglossakis, Chara Papadaki, Ippokratis Messaritakis, Nikolaos Vardakis
Purpose: To evaluate the clinical relevance of circulating CEACAM5mRNA-positive cells in patients with operable colorectal cancer (CRC).Methods: Peripheral blood was obtained from 265 patients with operable CRC before the initiation of adjuvant syste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::354a0921787d7a9474aad46db93721ad
https://doi.org/10.1158/1078-0432.c.6519362
https://doi.org/10.1158/1078-0432.c.6519362
Autor:
John Souglakos, Vassilis Georgoulias, Dimitris Mavroudis, Dora Hatzidaki, Maria Perraki, Ioannis Koutroubakis, Stella Apostolaki, Zacharenia Saridaki, Maria Sfakianaki, Georgios Agoglossakis, Chara Papadaki, Ippokratis Messaritakis, Nikolaos Vardakis
Supplementary Figures S1-S3; Supplementary Tables S1-S2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ef6af4ece5f9372145e8564df230724
https://doi.org/10.1158/1078-0432.22442690
https://doi.org/10.1158/1078-0432.22442690
Autor:
Maria Sfakianaki, Maria Tzardi, Konstantina Tsantaki, Chara Koutoulaki, Ippokratis Messaritakis, Galateia Datseri, Eleni Moustou, Dimitrios Mavroudis, John Souglakos
Publikováno v:
Cancers; Volume 15; Issue 2; Pages: 353
MMR gene germline mutations are considered a major genetic disorder in patients with hereditary nonpolyposis colon cancer (HNPCC) or Lynch syndrome; A total of 15% of sporadic colon carcinomas are MSI-High. MSI has also been observed in other cancers
Autor:
Ippokratis Messaritakis, Maria Stogiannitsi, Asimina Koulouridi, Maria Sfakianaki, Alexandra Voutsina, Afroditi Sotiriou, Elias Athanasakis, Evangelos Xynos, Dimitris Mavroudis, Maria Tzardi, John Souglakos
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0197327 (2018)
BACKGROUND:Toll-like receptors (TLRs) play essential role in innate and acquired immunity, are expressed in various cell types, and are associated with altered susceptibility to many diseases, and cancers. The aim of this study was to investigate TLR
Externí odkaz:
https://doaj.org/article/bd877238f2874b42aeb6bc4dd593db47
Autor:
Ippokratis Messaritakis, Eleni Politaki, Athanasios Kotsakis, Eleftheria-Kleio Dermitzaki, Filippos Koinis, Eleni Lagoudaki, Anastasios Koutsopoulos, Galatea Kallergi, John Souglakos, Vassilis Georgoulias
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0181211 (2017)
To evaluate the phenotypic heterogeneity of circulating tumor cells (CTCs) based on the expression of proliferative, apoptotic and Epithelial-to-Mesenchymal Transmission (EMT) markers during front-line treatment in patients with small cell lung cance
Externí odkaz:
https://doaj.org/article/7af8b3749b5d40adab4b55aede43e046