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pro vyhledávání: '"John, Sona"'
Autor:
John, Sona, Müller, Johannes
We investigate the evolutionary dynamics of an age-structured population under weak frequency-dependent selection. It turns out that the weak selection is affected in a non-trivial way by the life-history trait. We can disentangle the dynamics, based
Externí odkaz:
http://arxiv.org/abs/2212.09446
Mathematical modelling of epidemiological and coevolutionary dynamics is widely being used to improve disease management strategies of infectious diseases. Many diseases present some form of intra-host quiescent stage, also known as covert infection,
Externí odkaz:
http://arxiv.org/abs/2205.12714
Autor:
John, Sona, Müller, Johannes
Publikováno v:
In Mathematical Biosciences November 2023 365
Akademický článek
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Autor:
Jain, Kavita, John, Sona
Publikováno v:
Theo. Pop. Biol. 112, 117-125 (2016)
We study a continuous time model for the frequency distribution of an infinitely large asexual population in which both beneficial and deleterious mutations occur and the fitness is additive. When beneficial mutations are ignored, the exact solution
Externí odkaz:
http://arxiv.org/abs/1604.03676
Autor:
John, Sona, Seetharaman, Sarada
Publikováno v:
PLoS ONE 11(3): e0151795. March 18, 2016
Adaptation of asexual populations is driven by beneficial mutations and therefore the dynamics of this process, besides other factors, depend on the distribution of beneficial fitness effects. It is known that on uncorrelated fitness landscapes, this
Externí odkaz:
http://arxiv.org/abs/1503.01984
Autor:
Märkle, Hanna, John, Sona, Metzger, Lukas, Consortium, STOP-HCV, Ansari, M Azim, Pedergnana, Vincent, Tellier, Aurélien
Publikováno v:
Molecular Biology & Evolution; Sep2024, Vol. 41 Issue 9, p1-16, 16p
Publikováno v:
In Materials Today: Proceedings 2020 25 Part 2:230-235
Autor:
John, Sona, Jain, Kavita
Publikováno v:
J. theor. Biol. 365, 238-246 (2015)
We study the stationary state of a population evolving under the action of random genetic drift, selection and recombination in which both deleterious and reverse beneficial mutations can occur. We find that the equilibrium fraction of deleterious mu
Externí odkaz:
http://arxiv.org/abs/1308.0962
Autor:
živković, Daniel1 (AUTHOR) daniel.zivkovic@gmx.at, John, Sona1 (AUTHOR), Verin, Mélissa1,2 (AUTHOR), Stephan, Wolfgang3 (AUTHOR), Tellier, Aurélien1 (AUTHOR) tellier@wzw.tum.de
Publikováno v:
BMC Evolutionary Biology. 12/19/2019, Vol. 19 Issue 1, p1-11. 11p.