Zobrazeno 1 - 10
of 13
pro vyhledávání: '"John, Seavitt"'
Autor:
Lindsay Burrage, Denise Lanza, Paul Marcogliese, Di Lu, Chih-Wei Logan Hsu, Nathalie Aceves, Matthew Gonzalez, Audrey Christiansen, Tara Rasmussen, Angelina Gaspero, John Seavitt, Mary Dickinson, Brian Shayota, Stephanie Pachter, Debra-Lynn Day-Salvatore, Oguz Kanca, Michael Wangler, Lorraine Potocki, Jill Rosenfeld, Brendan Lee, Shinya Yamamoto, Hugo Bellen, Jason Heaney
Publikováno v:
Genetics in Medicine Open, Vol 2, Iss , Pp 101070- (2024)
Externí odkaz:
https://doaj.org/article/b6e725224c064b4684ffdeb3ba055845
Autor:
Eleanor Herbert, Michelle Stewart, Marie Hutchison, Ann M Flenniken, Dawei Qu, Lauryl M J Nutter, Colin McKerlie, Liane Hobson, Brenda Kick, Bonnie Lyons, Jean-Paul Wiegand, Rosalinda Doty, Juan Antonio Aguilar-Pimentel, Martin Hrabe de Angelis, Mary Dickinson, John Seavitt, Jacqueline K White, Cheryl L Scudamore, Sara Wells
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0230162 (2020)
Dislocation in hindlimb tarsals are being observed at a low, but persistent frequency in group-housed adult male mice from C57BL/6N substrains. Clinical signs included a sudden onset of mild to severe unilateral or bilateral tarsal abduction, swellin
Externí odkaz:
https://doaj.org/article/080643f202ae48d1931d33a2f5d1884e
Autor:
Michael R. Bowl, Michelle M. Simon, Neil J. Ingham, Simon Greenaway, Luis Santos, Heather Cater, Sarah Taylor, Jeremy Mason, Natalja Kurbatova, Selina Pearson, Lynette R. Bower, Dave A. Clary, Hamid Meziane, Patrick Reilly, Osamu Minowa, Lois Kelsey, The International Mouse Phenotyping Consortium, Glauco P. Tocchini-Valentini, Xiang Gao, Allan Bradley, William C. Skarnes, Mark Moore, Arthur L. Beaudet, Monica J. Justice, John Seavitt, Mary E. Dickinson, Wolfgang Wurst, Martin Hrabe de Angelis, Yann Herault, Shigeharu Wakana, Lauryl M. J. Nutter, Ann M. Flenniken, Colin McKerlie, Stephen A. Murray, Karen L. Svenson, Robert E. Braun, David B. West, K. C. Kent Lloyd, David J. Adams, Jacqui White, Natasha Karp, Paul Flicek, Damian Smedley, Terrence F. Meehan, Helen E. Parkinson, Lydia M. Teboul, Sara Wells, Karen P. Steel, Ann-Marie Mallon, Steve D. M. Brown
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
The full extent of the genetic basis for hearing impairment is unknown. Here, as part of the International Mouse Phenotyping Consortium, the authors perform a hearing loss screen in 3006 mouse knockout strains and identify 52 new candidate genes for
Externí odkaz:
https://doaj.org/article/c71478f2406844f6901b4df53eb1c02c
Akademický článek
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Autor:
Morisada, Hayakawa, Hiroko, Hayakawa, Tsvetana, Petrova, Patcharee, Ritprajak, Ruhcha V, Sutavani, Guillermina Yanek, Jiménez-Andrade, Yasuyo, Sano, Min-Kyung, Choo, John, Seavitt, Ram K C, Venigalla, Kinya, Otsu, Katia, Georgopoulos, J Simon C, Arthur, Jin Mo, Park
Publikováno v:
The Journal of Biological Chemistry
The evolutionarily conserved protein kinase p38 mediates innate resistance to environmental stress and microbial infection. Four p38 isoforms exist in mammals and may have been co-opted for new roles in adaptive immunity. Murine T cells deficient in
Publikováno v:
Journal of Biological Chemistry. 277:13007-13015
Ikaros is essential for the normal development and regulated proliferation of lymphoid cells. In lymphocytes, Ikaros exists as an integral component of chromatin-remodeling complexes, including the Mi-2beta/nucleosome remodeling and deacetylation com
Autor:
Chun Kung, Michelle Noll, John Seavitt, Jeanette T. Pingel, Matthew L. Thomas, Lynn S. White, Meinoshin Okumura
Publikováno v:
European Journal of Immunology. 29:3951-3955
CD45 is a transmembrane protein tyrosine phosphatase required for signaling through the T-and B-cell antigen receptors. In lymphocytes, CD45 interacts with CD45-associated protein (CD45AP), a 32 000 Mr phosphoprotein, through their respective transme
Autor:
Taku Naito, Audrey F. Jackson, Marei Dose, John Seavitt, Jiangwen Zhang, Feifei Liu, Fotini Gounari, Howard T. Petrie, Elizabeth J. Heller, Toshimi Yoshida, Katia Georgopoulos, Mariko Kashiwagi
Publikováno v:
Nature immunology
Cell fate depends on the interplay between chromatin regulators and transcription factors. Here we show that activity of the Mi-2β nucleosome-remodeling and histone-deacetylase (NuRD) complex was controlled by the Ikaros family of lymphoid lineage-d
Autor:
Pablo Gómez-del Arco, Taku Naito, Katia Georgopoulos, Christine J. Williams, Toshimi Yoshida, John Seavitt
Publikováno v:
Zinc Finger Proteins ISBN: 9780306482298
In many developmental systems, nuclear regulators have been implicated in coupling key events in gene expression with specific cell fate and lineage decisions. In the hemo-lymphoid system, the Ikaros gene family of zinc finger DNA binding factors con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::529ac05d808ae548a1fc1c5c60ab40c9
https://doi.org/10.1007/0-387-27421-9_27
https://doi.org/10.1007/0-387-27421-9_27
Autor:
Christine J. Williams, Katia Georgopoulos, Ulrich H. von Andrian, Piper Keables, Beverly De Souza, Susan M Cashman, Taku Naito, John Seavitt, Pablo Gómez-del Arco, Xiaoqing Qi
Publikováno v:
Immunity. 20(6)
Changes in chromatin structure underlie the activation or silencing of genes during development. The chromatin remodeler Mi-2beta is highly expressed in thymocytes and is presumed to be a transcriptional repressor because of its presence in the nucle