Zobrazeno 1 - 10
of 22
pro vyhledávání: '"John, Sargeant"'
Autor:
John, Sargeant, Jesse C, Hay
Publikováno v:
Faculty reviews. 11
Constitutive vesicle trafficking is the default pathway used by all cells for movement of intracellular cargoes between subcellular compartments and in and out of the cell. Classically, constitutive trafficking was thought to be continuous and unregu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fffee77de269e4e207d770479e7b90bf
https://pubmed.ncbi.nlm.nih.gov/35359486
https://pubmed.ncbi.nlm.nih.gov/35359486
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0157227 (2016)
Luminal calcium regulates vesicle transport early in the secretory pathway. In ER-to-Golgi transport, depletion of luminal calcium leads to significantly reduced transport and a buildup of budding and newly budded COPII vesicles and vesicle proteins.
Externí odkaz:
https://doaj.org/article/584a5bc1aa5d4d22b67b076ccf28bdd8
Autor:
John Sargeant, Jesse C Hay
Publikováno v:
Faculty Reviews. 11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20d69b0637601fe191a27cd388b29ad6
https://doi.org/10.12703/r/11-6
https://doi.org/10.12703/r/11-6
Autor:
Delia Fuhrmann, David Nesbitt, Meredith Shafto, James B. Rowe, Darren Price, Andrew Gadie, Rogier A. Kievit, Lorraine K. Tyler, Carol Brayne, Edward T. Bullmore, Andrew C. Calder, Rhodri Cusack, Tim Dalgleish, John Duncan, Richard N. Henson, Fiona E. Matthews, William D. Marslen-Wilson, Meredith A. Shafto, Karen Campbell, Teresa Cheung, Simon Davis, Linda Geerligs, Rogier Kievit, Anna McCarrey, Abdur Mustafa, David Samu, Jason R. Taylor, Matthias Treder, Kamen Tsvetanov, Janna van Belle, Nitin Williams, Lauren Bates, Tina Emery, Sharon Erzinlioglu, Sofia Gerbase, Stanimira Georgieva, Claire Hanley, Beth Parkin, David Troy, Tibor Auer, Marta Correia, Lu Gao, Emma Green, Rafael Henriques, Jodie Allen, Gillian Amery, Liana Amunts, Anne Barcroft, Amanda Castle, Cheryl Dias, Jonathan Dowrick, Melissa Fair, Hayley Fisher, Anna Goulding, Adarsh Grewal, Geoff Hale, Andrew Hilton, Frances Johnson, Patricia Johnston, Thea Kavanagh-Williamson, Magdalena Kwasniewska, Alison McMinn, Kim Norman, Jessica Penrose, Fiona Roby, Diane Rowland, John Sargeant, Maggie Squire, Beth Stevens, Aldabra Stoddart, Cheryl Stone, Tracy Thompson, Ozlem Yazlik, Dan Barnes, Marie Dixon, Jaya Hillman, Joanne Mitchell, Laura Villis
Publikováno v:
Neurobiology of Aging
2019, ' Strong and specific associations between cardiovascular risk factors and white matter micro-and macrostructure in healthy aging ', Neurobiology of Aging, vol. 74, pp. 46-55 . https://doi.org/10.1016/j.neurobiolaging.2018.10.005
2019, ' Strong and specific associations between cardiovascular risk factors and white matter micro-and macrostructure in healthy aging ', Neurobiology of Aging, vol. 74, pp. 46-55 . https://doi.org/10.1016/j.neurobiolaging.2018.10.005
Cardiovascular health declines with age, increasing the risk of hypertension and elevated heart rate in middle and old age. Here, we used multivariate techniques to investigate the associations between cardiovascular health (diastolic blood pressure,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e09d15821e098e63658a2cd3692b1b0
http://europepmc.org/articles/PMC6338676
http://europepmc.org/articles/PMC6338676
Autor:
John Sargeant, Aaron Held, Wolfgang F. Graier, Roland Mali, Jesse C. Hay, Corina T. Madreiter-Sokolowski, Jennet Hojanazarova
Ca2+ release by inositol trisphosphate receptors (IP3Rs) regulates diverse physiological processes in many cell types. Notably, agonist-stimulated Ca2+ signaling involving IP3Rs can modulate ER export rates through activation of the Ca2+-dependent ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb76dc1273e63e1fff70eefbb6365cb8
https://doi.org/10.1101/2020.06.13.150144
https://doi.org/10.1101/2020.06.13.150144
Autor:
Andrew A. Peden, Jesse C. Ray, Corina T. Madreiter-Sokolowski, Tucker Costain, Wolfgang F. Graier, David E. Gordon, John Sargeant, Danette Kowal Seiler, Roland Malli
ER-to-Golgi transport is the first step in the constitutive secretory pathway which, unlike regulated secretion, is believed to proceed non-stop regardless of Ca2+ flux. Rowever, here we demonstrate that penta-EF hand (PEF) proteins ALG-2 and peflin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec26638046f44068608d217236ae904c
https://doi.org/10.1101/2020.02.22.944264
https://doi.org/10.1101/2020.02.22.944264
Autor:
Noham Wolpe, James N. Ingram, Kamen A. Tsvetanov, Richard N. Henson, Daniel M. Wolpert, James B. Rowe, Lorraine K. Tyler, Carol Brayne, Edward T. Bullmore, Andrew C. Calder, Rhodri Cusack, Tim Dalgleish, John Duncan, Fiona E. Matthews, William D. Marslen-Wilson, Meredith A. Shafto, Karen Campbell, Teresa Cheung, Simon Davis, Linda Geerligs, Rogier Kievit, Anna McCarrey, Abdur Mustafa, Darren Price, David Samu, Jason R. Taylor, Matthias Treder, Janna van Belle, Nitin Williams, Lauren Bates, Tina Emery, Sharon Erzinçlioglu, Andrew Gadie, Sofia Gerbase, Stanimira Georgieva, Claire Hanley, Beth Parkin, David Troy, Tibor Auer, Marta Correia, Lu Gao, Emma Green, Rafael Henriques, Jodie Allen, Gillian Amery, Liana Amunts, Anne Barcroft, Amanda Castle, Cheryl Dias, Jonathan Dowrick, Melissa Fair, Hayley Fisher, Anna Goulding, Adarsh Grewal, Geoff Hale, Andrew Hilton, Frances Johnson, Patricia Johnston, Thea Kavanagh-Williamson, Magdalena Kwasniewska, Alison McMinn, Kim Norman, Jessica Penrose, Fiona Roby, Diane Rowland, John Sargeant, Maggie Squire, Beth Stevens, Aldabra Stoddart, Cheryl Stone, Tracy Thompson, Ozlem Yazlik, Dan Barnes, Marie Dixon, Jaya Hillman, Joanne Mitchell, Laura Villis
Publikováno v:
Neurobiology of Aging
The adaption of movement to changes in the environment varies across life span. Recent evidence has linked motor adaptation and its reduction with age to differences in “explicit” learning processes. We examine differences in brain structure and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ca4a8697563723115f5f70a9de6fe93
Autor:
Corina T. Madreiter-Sokolowski, Wolfgang F. Graier, Jesse C. Hay, Roland Malli, Andrew A. Peden, John Sargeant, Danette Kowal Seiler, David E. Gordon, Tucker Costain
Publikováno v:
The Journal of Biological Chemistry
ER-to-Golgi transport is the first step in the constitutive secretory pathway, which, unlike regulated secretion, is believed to proceed non-stop independent of Ca2+ flux. However, here we demonstrate that penta-EF hand (PEF) proteins ALG-2 and pefli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::152f9c4836983b55e1ef3d9b28347ac6
https://doi.org/10.1016/j.jbc.2021.101393
https://doi.org/10.1016/j.jbc.2021.101393
Autor:
Darren Price, Fiona Roby, John Sargeant, Andrew C. Calder, Andrew Hilton, Kim Norman, Cheryl Dias, Liana Amunts, Stanimira Georgieva, Adarsh Grewal, Jonathan Dowrick, Tim Dalgleish, Ozlem Yazlik, Karen L. Campbell, Beth L. Parkin, Geoff Hale, Diane Rowland, Abdur Mustafa, Melissa Fair, James B. Rowe, Cheryl Stone, David Samu, Gillian Amery, Kamen A. Tsvetanov, Tibor Auer, Claire J. Hanley, Jodie Allen, Lorraine K. Tyler, Anna Goulding, Fiona E. Matthews, Laura Villis, Maggie Squire, John S. Duncan, Carol Brayne, David Troy, Hayley Fisher, Rogier A. Kievit, Sofia Gerbase, Amanda Castle, Jason R. Taylor, Thea Kavanagh-Williamson, Simon W. Davis, Alison McMinn, Anna McCarrey, Frances Johnson, Jaya Hillman, Janna van Belle, Joanne Mitchell, Anne Barcroft, Magdalena Kwasniewska, Sharon Erzinglioglu, Lauren Bates, Emma Green, Teresa Cheung, Beth Stevens, Marie Dixon, R. Neto Henriques, Rhodri Cusack, Nitin Williams, Meredith A. Shafto, Linda Geerligs, Marta Correia, Richard N. Henson, Matthias S. Treder, Andrew Gadie, Dan Barnes, Cam-CAN, Aldabra Stoddart, Jessica Penrose, Tina Emery, William D. Marslen-Wilson, Edward T. Bullmore, Patricia Johnston, Lu Gao, Tracy Thompson
Publikováno v:
Nature Communications
Price, D, Tyler, L K, Henriques, R N, Campbell, K, Williams, N, Treder, M, Taylor, J, Cam-CAN & Henson, R N A 2017, ' Age-related delay in visual and auditory evoked responses is mediated by white-and gray-matter differences ', Nature Communications, vol. 8, 15671 . https://doi.org/10.1038/ncomms15671
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Price, D, Tyler, L K, Henriques, R N, Campbell, K, Williams, N, Treder, M, Taylor, J, Cam-CAN & Henson, R N A 2017, ' Age-related delay in visual and auditory evoked responses is mediated by white-and gray-matter differences ', Nature Communications, vol. 8, 15671 . https://doi.org/10.1038/ncomms15671
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Slowing is a common feature of ageing, yet a direct relationship between neural slowing and brain atrophy is yet to be established in healthy humans. We combine magnetoencephalographic (MEG) measures of neural processing speed with magnetic resonance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ba51f8b65ce84e4bd99c240ef9ff743
https://orca.cardiff.ac.uk/id/eprint/108242/1/ncomms15671.pdf
https://orca.cardiff.ac.uk/id/eprint/108242/1/ncomms15671.pdf
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0157227 (2016)
PLoS ONE
PLoS ONE
Luminal calcium regulates vesicle transport early in the secretory pathway. In ER-to-Golgi transport, depletion of luminal calcium leads to significantly reduced transport and a buildup of budding and newly budded COPII vesicles and vesicle proteins.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37ce3ffb786604a01a46f4677dd220cf
http://europepmc.org/articles/PMC4898701?pdf=render
http://europepmc.org/articles/PMC4898701?pdf=render