Zobrazeno 1 - 10
of 106
pro vyhledávání: '"John, Rek"'
Autor:
Moses R Kamya, Joaniter I Nankabirwa, Emmanuel Arinaitwe, John Rek, Maato Zedi, Catherine Maiteki-Sebuguzi, Jimmy Opigo, Sarah G Staedke, Ambrose Oruni, Martin J Donnelly, Bryan Greenhouse, Jessica Briggs, Paul J Krezanoski, Teun Bousema, Philip J Rosenthal, Peter Olwoch, Prasanna Jagannathan, Isabel Rodriguez-Barraquer, Grant Dorsey
Publikováno v:
PLOS Global Public Health, Vol 4, Iss 8, p e0003254 (2024)
Tororo District, Uganda experienced a dramatic decrease in malaria burden from 2015-19 during 5 years of indoor residual spraying (IRS) with carbamate (Bendiocarb) and then organophosphate (Actellic) insecticides. However, a marked resurgence occurre
Externí odkaz:
https://doaj.org/article/3c0662931cfd417898f2f748766286e6
Autor:
Chiara Andolina, Jordache Ramjith, John Rek, Kjerstin Lanke, Joseph Okoth, Lynn Grignard, Emmanuel Arinaitwe, Jessica Briggs, Jeffrey Bailey, Ozkan Aydemir, Moses R. Kamya, Bryan Greenhouse, Grant Dorsey, Sarah G. Staedke, Chris Drakeley, Marianne Jonker, Teun Bousema
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Malaria transmission depends on the presence of Plasmodium gametocytes that are the only parasite life stage that can infect mosquitoes. Gametocyte production varies between infections and over the course of infections. Infection duration is
Externí odkaz:
https://doaj.org/article/dbd682f07da74bc2a08222cc94ab0c03
Autor:
Jo-Anne Chan, Jessica R. Loughland, Lauren de la Parte, Satomi Okano, Isaac Ssewanyana, Mayimuna Nalubega, Felistas Nankya, Kenneth Musinguzi, John Rek, Emmanuel Arinaitwe, Peta Tipping, Peter Bourke, Dean Andrew, Nicholas Dooley, Arya SheelaNair, Bruce D. Wines, P. Mark Hogarth, James G. Beeson, Bryan Greenhouse, Grant Dorsey, Moses Kamya, Gunter Hartel, Gabriela Minigo, Margaret Feeney, Prasanna Jagannathan, Michelle J. Boyle
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Despite being key drivers of protective antibodies against malaria, little is known regarding the host and parasite factors that influence CD4 T-follicular helper cell and antibody development. Authors utilise samples from a study of children living
Externí odkaz:
https://doaj.org/article/cbf04ed2b51b46b3bbb1c106a6ca7595
Autor:
Margaux L. Sadoine, Audrey Smargiassi, Ying Liu, Philippe Gachon, Guillaume Dueymes, Grant Dorsey, Michel Fournier, Joaniter I. Nankabirwa, John Rek, Kate Zinszer
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Studies have estimated the impact of the environment on malaria incidence although few have explored the differential impact due to malaria control interventions. Therefore, the objective of the study was to evaluate the effect of indoor res
Externí odkaz:
https://doaj.org/article/e1f292e5303a40cca51eb2a2127fc2c2
Autor:
Madhura Raghavan, Katrina L Kalantar, Elias Duarte, Noam Teyssier, Saki Takahashi, Andrew F Kung, Jayant V Rajan, John Rek, Kevin KA Tetteh, Chris Drakeley, Isaac Ssewanyana, Isabel Rodriguez-Barraquer, Bryan Greenhouse, Joseph L DeRisi
Publikováno v:
eLife, Vol 12 (2023)
Protection against Plasmodium falciparum, which is primarily antibody-mediated, requires recurrent exposure to develop. The study of both naturally acquired limited immunity and vaccine induced protection against malaria remains critical for ongoing
Externí odkaz:
https://doaj.org/article/06c54b0a070b4fe3917510b1a5dbd1e7
Autor:
Lusajo Mwakibete, Saki Takahashi, Vida Ahyong, Allison Black, John Rek, Isaac Ssewanyana, Moses Kamya, Grant Dorsey, Prasanna Jagannathan, Isabel Rodríguez-Barraquer, Cristina M Tato, Bryan Greenhouse
Publikováno v:
PLOS Global Public Health, Vol 3, Iss 5, p e0001675 (2023)
Causes of non-malarial fevers in sub-Saharan Africa remain understudied. We hypothesized that metagenomic next-generation sequencing (mNGS), which allows for broad genomic-level detection of infectious agents in a biological sample, can systematicall
Externí odkaz:
https://doaj.org/article/41fafc9dc1a84442869f2a38416b1de8
Autor:
Paul J. Krezanoski, Michelle E. Roh, John Rek, Joaniter I. Nankabirwa, Emmanuel Arinaitwe, Sarah G. Staedke, Susan Nayiga, Michelle S. Hsiang, David Smith, Moses Kamya, Grant Dorsey
Publikováno v:
BMC Medicine, Vol 19, Iss 1, Pp 1-9 (2021)
Abstract Background Intensive malaria control may have additional benefits beyond reducing the incidence of symptomatic malaria. We compared antibiotic treatment of children before and after the implementation of highly effective malaria control inte
Externí odkaz:
https://doaj.org/article/2131815dbe4f4c7b994f5578646d1442
Autor:
Jessica Briggs, Alison Kuchta, Max Murphy, Sofonias Tessema, Emmanuel Arinaitwe, John Rek, Anna Chen, Joaniter I. Nankabirwa, Chris Drakeley, David Smith, Teun Bousema, Moses Kamya, Isabel Rodriguez-Barraquer, Sarah Staedke, Grant Dorsey, Philip J. Rosenthal, Bryan Greenhouse
Publikováno v:
Malaria Journal, Vol 20, Iss 1, Pp 1-8 (2021)
Abstract Background Evaluation of genetic relatedness of malaria parasites is a useful tool for understanding transmission patterns, but patterns are not easily detectable in areas with moderate to high malaria transmission. To evaluate the feasibili
Externí odkaz:
https://doaj.org/article/1b26c402ff274818ad507c1d6b82d660
Autor:
Stephen Tukwasibwe, James A. Traherne, Olympe Chazara, Jyothi Jayaraman, John Trowsdale, Ashley Moffett, Wei Jiang, Joaniter I. Nankabirwa, John Rek, Emmanuel Arinaitwe, Samuel L. Nsobya, Maxine Atuheirwe, Mubiru Frank, Anguzu Godwin, Prasanna Jagannathan, Stephen Cose, Moses R. Kamya, Grant Dorsey, Philip J. Rosenthal, Francesco Colucci, Annettee Nakimuli
Publikováno v:
Malaria Journal, Vol 20, Iss 1, Pp 1-11 (2021)
Abstract Background Malaria is one of the most serious infectious diseases in the world. The malaria burden is greatly affected by human immunity, and immune responses vary between populations. Genetic diversity in KIR and HLA-C genes, which are impo
Externí odkaz:
https://doaj.org/article/43d22a087802415eb09d389bde9ea02e
Autor:
Emmanuel Arinaitwe, Joaniter I. Nankabirwa, Paul Krezanoski, John Rek, Victor Kamya, Adrienne Epstein, Philip J. Rosenthal, Chris Drakeley, Moses R. Kamya, Grant Dorsey, Sarah G. Staedke
Publikováno v:
Malaria Journal, Vol 19, Iss 1, Pp 1-10 (2020)
Abstract Background The burden of malaria in Uganda remains high, but has become increasingly heterogenous following intensified malaria control. Travel within Uganda is recognized as a risk factor for malaria, but behaviours associated with travel a
Externí odkaz:
https://doaj.org/article/2dfe459b1b4342da84739dc059c0abde