Zobrazeno 1 - 10
of 113
pro vyhledávání: '"John, Reece"'
Autor:
Merve Mutlu, Isabel Schmidt, Andrew I. Morrison, Benedikt Goretzki, Felix Freuler, Damien Begue, Oliver Simic, Nicolas Pythoud, Erik Ahrne, Sandra Kapps, Susan Roest, Debora Bonenfant, Delphine Jeanpierre, Thi-Thanh-Thao Tran, Rob Maher, Shaojian An, Amandine Rietsch, Florian Nigsch, Andreas Hofmann, John Reece-Hoyes, Christian N. Parker, Danilo Guerini
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Stimulator of interferon genes (STING) is a central component of the cytosolic nucleic acids sensing pathway and as such master regulator of the type I interferon response. Due to its critical role in physiology and its’ involvement in a v
Externí odkaz:
https://doaj.org/article/d64305878b7f4abe9dd92a3040e7b4f4
Autor:
Jie Li, Francesca Moretti, Tunda Hidvegi, Sanja Sviben, James A.J. Fitzpatrick, Hemalatha Sundaramoorthi, Stephen C. Pak, Gary A. Silverman, Britta Knapp, Ireos Filipuzzi, John Alford, John Reece-Hoyes, Florian Nigsch, Leon O. Murphy, Beat Nyfeler, David H. Perlmutter
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 17, Iss 6, Pp 1007-1024 (2024)
Background & Aims: In the classic form of α1-antitrypsin deficiency (ATD), the misfolded α1-antitrypsin Z (ATZ) variant accumulates in the endoplasmic reticulum (ER) of liver cells. A gain-of-function proteotoxic mechanism is responsible for chroni
Externí odkaz:
https://doaj.org/article/732b690fbbd84589915ab3fbdd2ec291
Autor:
Jeannette Milgrom, Yafit Hirshler, Charlene Holt, Helen Skouteris, Megan Galbally, Christine East, Vivette Glover, John Reece, Kieran J. O’Donnell, Susan P. Walker, Shannon Malloy, Alan W. Gemmill
Publikováno v:
BMC Psychology, Vol 11, Iss 1, Pp 1-11 (2023)
Abstract Background Substantial evidence indicates that maternal depression during pregnancy (i.e., antenatal depression) is associated not only with maternal wellbeing but also with child emotional and behavioural development. Children of antenatall
Externí odkaz:
https://doaj.org/article/686b454646f04926bc0ed1154eab9428
Autor:
George M. Hillman Jr, John Reece
What can the Church learn from the business world? You're a leader of a ministry, nonprofit, or church. You trained to be a faithful counselor, preacher, interpreter of God's Word—so why do you find yourself spending so much energy on administratio
Autor:
Carlos G. Sanchez, Christopher M. Acker, Audrey Gray, Malini Varadarajan, Cheng Song, Nadire R. Cochran, Steven Paula, Alicia Lindeman, Shaojian An, Gregory McAllister, John Alford, John Reece-Hoyes, Carsten Russ, Lucas Craig, Ketthsy Capre, Christian Doherty, Gregory R. Hoffman, Sarah J. Luchansky, Manuela Polydoro, Ricardo Dolmetsch, Fiona Elwood
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Using an unbiased genome-wide CRISPR screen approach, Sanchez et al. identified modulators of endogenous tau protein. This study suggests that chromatin modifiers, neddylation, ubiquitination, and the mTOR pathways regulate overall levels of tau prot
Externí odkaz:
https://doaj.org/article/a6974f96fa3e43eca73250a0892da4a2
Autor:
Nicolas Mercado, Gabi Schutzius, Christian Kolter, David Estoppey, Sebastian Bergling, Guglielmo Roma, Caroline Gubser Keller, Florian Nigsch, Adrian Salathe, Remi Terranova, John Reece-Hoyes, John Alford, Carsten Russ, Judith Knehr, Dominic Hoepfner, Alexandra Aebi, Heinz Ruffner, Tanner C. Beck, Sajjeev Jagannathan, Calla M. Olson, Hadley E. Sheppard, Selma Z. Elsarrag, Tewis Bouwmeester, Mathias Frederiksen, Felix Lohmann, Charles Y. Lin, Susan Kirkland
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-19 (2019)
Epidermal homeostasis requires long term stem cell function. Here, the authors apply transcriptional circuitry analysis based on integrated epigenomic profiling of primary human keratinocytes with high and low stem cell function to identify IRF2 as a
Externí odkaz:
https://doaj.org/article/0f22070deb8646359f9b585b7f128992
Publikováno v:
Journal of the European Ceramic Society. 43:177-182
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::740572311a05188fc36932afb7bebed8
https://doi.org/10.1016/j.jeurceramsoc.2022.09.045
https://doi.org/10.1016/j.jeurceramsoc.2022.09.045
Autor:
Ping Zhang, Mengjie Qin, Zhihao Lou, Shuyao Cao, Lingyun Gong, Jie Xu, Michael John Reece, Haixue Yan, Zinovi Dashevsky, Feng Gao
Publikováno v:
Journal of the European Ceramic Society. 42:7017-7026
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ffa474303802e32a59010bbf619fc9b2
https://doi.org/10.1016/j.jeurceramsoc.2022.08.009
https://doi.org/10.1016/j.jeurceramsoc.2022.08.009
Autor:
Marek J Kobylarz, Jonathan M Goodwin, Zhao B Kang, John W Annand, Sarah Hevi, Ellen O'Mahony, Gregory McAllister, John Reece-Hoyes, Qiong Wang, John Alford, Carsten Russ, Alicia Lindeman, Martin Beibel, Guglielmo Roma, Walter Carbone, Judith Knehr, Joseph Loureiro, Christophe Antczak, Dmitri Wiederschain, Leon O Murphy, Suchithra Menon, Beat Nyfeler
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0235551 (2020)
VPS34 is a key regulator of endomembrane dynamics and cargo trafficking, and is essential in cultured cell lines and in mice. To better characterize the role of VPS34 in cell growth, we performed unbiased cell line profiling studies with the selectiv
Externí odkaz:
https://doaj.org/article/405ec165a99f440886a38bc379ff0399
Autor:
Zimeng Hu, Gavin B. G. Stenning, Vladimir Koval, Jiyue Wu, Bin Yang, Alisa Leavesley, Richard Wylde, Michael John Reece, Chenglong Jia, Haixue Yan
Publikováno v:
ACS Applied Materials & Interfaces. 14:46738-46747
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f7ada918da16c2dc43e61748512f18a
https://doi.org/10.1021/acsami.2c13088
https://doi.org/10.1021/acsami.2c13088