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pro vyhledávání: '"John, Ramphal"'
Autor:
Linley Mangini, Roger Lawrence, Manuel E. Lopez, Timothy C. Graham, Christopher R. Bauer, Hang Nguyen, Cheng Su, John Ramphal, Brett E. Crawford, Tom A. Hartl
Publikováno v:
JIMD Reports, Vol 65, Iss 4, Pp 280-294 (2024)
Abstract Classic galactosemia (CG) arises from loss‐of‐function mutations in the Galt gene, which codes for the enzyme galactose‐1‐phosphate uridylyltransferase (GALT), a central component in galactose metabolism. The neonatal fatality associ
Externí odkaz:
https://doaj.org/article/681f476298fc43008be14cb90904e903
Autor:
James G, Christensen, Randall, Schreck, Jon, Burrows, Poonam, Kuruganti, Emily, Chan, Phuong, Le, Jeffrey, Chen, Xueyan, Wang, Lany, Ruslim, Robert, Blake, Kenneth E, Lipson, John, Ramphal, Steven, Do, Jingrong J, Cui, Julie M, Cherrington, Dirk B, Mendel
Publikováno v:
Cancer research. 63(21)
The c-Met receptor tyrosine kinase and its ligand, hepatocyte growth factor (HGF), have been implicated in the development and progression of several human cancers and are attractive targets for cancer therapy. PHA-665752 was identified as a small mo
Publikováno v:
Bioorganicmedicinal chemistry. 11(8)
Protein tyrosine phosphatases (PTPs) are important in the regulation of signal transduction processes. Certain enzymes of this class are considered as potential therapeutic targets in the treatment of a variety of diseases such as diabetes, inflammat
Autor:
John Ramphal, Harold W. Heine, Elizabeth A. Williams, David K. Williams, Jennifer L. Rutherford
Publikováno v:
HETEROCYCLES. 35:1125
o-Quinone monoimides undergo inverse electron demand Diels-Alder reactions with thiophene, 2-alkylated thiophenes, 2-and 2,5-alkylated furans and benzofurans. 2,5-Dimethylthiophenes and 2-methylbenzo[b]thiophene, on the other hand interact with o-qui