Výsledky vyhledávání - "John, Piletz"

Akademický článek

Altered plasma levels of arginine metabolites in depression

Autor: Ozden, Arisoy, Angelos, Halaris, Feyza, Aricioglu, Elizabeth, Wild, John, Piletz

Publikováno v: In Journal of Psychiatric Research January 2020 120:21-28

Comparison of ligand binding affinities at human I1-imidazoline binding sites and the high affinity state of alpha-2 adrenoceptor subtypes

Autor: John Piletz, Zhu H, Dn, Chikkala

Publikováno v: Europe PubMed Central

To identify selective compounds for nonadrenergic I1-imidazoline receptors (I1), the affinities of 22 ligands for [125I]p-iodoclonidine binding have been compared at human platelet I1-imidazoline binding sites (analyzed under norepinephrine mask of a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::82db66a85ac5352865df122d07eac377
https://pubmed.ncbi.nlm.nih.gov/8930173

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Comparison of the properties of agmatine and endogenous clonidine-displacing substance at imidazoline and alpha-2 adrenergic receptors

Autor: John Piletz, Dn, Chikkala, Ernsberger P

Publikováno v: Europe PubMed Central

Nonadrenergic imidazoline receptors (I receptors) mediate the central antihypertensive effects of clonidine. Agmatine, an arginine metabolite that is synthesized within bovine brain and exhibits clonidine-displacing substance (CDS) activity, might be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::2855e70a746977b619d09aacd3fb28fa
https://pubmed.ncbi.nlm.nih.gov/7853171

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Psychopharmacology of imidazoline and alpha 2-adrenergic receptors: implications for depression

Autor: John Piletz, Halaris A, Pr, Ernsberger

Publikováno v: Europe PubMed Central

The literature on alpha 2-adrenoceptors in depression is replete with seemingly contradictory findings, including reports of both hypersensitive and hyposensitive alterations. Now, with the discovery of nonadrenergic imidazoline receptors (I receptor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::55f659f7e7fd90b2a995fe2bd85a8dc3
http://europepmc.org/abstract/med/8828003

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MHPG circadian rhythmicity in blood of healthy subjects

Autor: Marler M, Halaris A, John Piletz

Publikováno v: Scopus-Elsevier
Europe PubMed Central

An earlier study showed that plasma concentrations of total 3-methoxy-4-hydroxyphenylglycol (MHPG), the major metabolite of norepinephrine, display a circadian rhythm in 6 male healthy subjects. In the previous study, the period of the rhythm was not

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6514314b53165bbfcf9b375a7ffaf021
http://www.scopus.com/inward/record.url?eid=2-s2.0-0025048542&partnerID=MN8TOARS

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Elevated 3H-para-aminoclonidine binding to platelet purified plasma membranes from depressed patients

Autor: John Piletz, Halaris, A., Saran, A., Marler, M.

Publikováno v: Europe PubMed Central
Scopus-Elsevier

Purified platelet plasma membranes were used to compare 3H-para-aminoclonidine binding in 18 depressed patients and 24 sex- and age-matched, healthy control subjects. Two site-selective concentrations of the radioligand were used (0.06 and 1.5 nmol/L

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::7ab7e8bdcd2a0b1f194583ff8a35b6ab
http://europepmc.org/abstract/med/1973039

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