Zobrazeno 1 - 8
of 8
pro vyhledávání: '"John, Pawelek"'
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0168581 (2017)
BACKGROUND:Metastatic disease is the principal cause of mortality in cancer, yet the underlying mechanisms are not fully understood. Macrophage-cancer cell fusion as a cause of metastasis was proposed more than a century ago by German pathologist Pro
Externí odkaz:
https://doaj.org/article/74a6dbe9fe9743738e09f1512dd2d3d1
Publikováno v:
Cells, Vol 8, Iss 2, p 170 (2019)
According to estimates from the International Agency for Research on Cancer, by the year 2030 there will be 22 million new cancer cases and 13 million deaths per year. The main cause of cancer mortality is not the primary tumor itself but metastasis
Externí odkaz:
https://doaj.org/article/3d8504a5c8714b63b56b9c1c7e57cdc9
Autor:
Greggory S, LaBerge, Eric, Duvall, Zachary, Grasmick, Kay, Haedicke, Anjela, Galan, Jesse, Leverett, Sudhir, Baswan, Sunghan, Yim, John, Pawelek
Publikováno v:
The Yale Journal of Biology and Medicine
The relationship between skin color and skin cancer is well established: the less melanin in one’s skin the greater the risk for developing skin cancer. This review is in two parts. First, we summarize the current understanding of the cutaneous pig
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1409
Tumor-targeted Salmonella offers a promising approach to the delivery of therapeutics for the treatment of cancer. The Salmonella strains used, however, must be stably attenuated in order to provide sufficient safety for administration. Approaches to
Publikováno v:
Pigment cellmelanoma research. 25(1)
There is evidence that L-tyrosine and L-dihydroxyphenylalanine (L-DOPA), besides serving as substrates and intermediates of melanogenesis, are also bioregulatory agents acting not only as inducers and positive regulators of melanogenesis but also as
Autor:
John, Pawelek, Ashok, Chakraborty, Rossita, Lazova, Yesim, Yilmaz, Dennis, Cooper, Douglas, Brash, Tamara, Handerson
Publikováno v:
Contributions to microbiology. 13
Tumor-associated macrophages (TAMs) play multiple roles in tumor initiation and progression. Tumors frequently appear in areas of chronic inflammation. This is likely aided by the mutagenic actions of macrophages. Tumor growth and progression is supp
Autor:
John Pawelek
Publikováno v:
Pigment Cell Research. 7:107-108
Autor:
John Pawelek
Publisher Summary This chapter focuses on melanoma cells. Melanocytes synthesize melanin in a reaction controlled by the enzyme monophenyl, dihydroxyphenylalanine: oxygen oxidoreductase. Melanocytes in the skin of adult mammals divide infrequently, p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86b4a0b508376a332cd441ff6c5c3d03
https://doi.org/10.1016/s0076-6879(79)58172-5
https://doi.org/10.1016/s0076-6879(79)58172-5