Zobrazeno 1 - 10
of 57
pro vyhledávání: '"John, Palcza"'
Autor:
Wendy Ankrom, Phung Bondiskey, Chi‐Chung Li, John Palcza, Wen Liu, Marissa F. Dockendorf, Catherine Matthews, Deborah Panebianco, Tom Reynders, John A. Wagner, Abhijeet Jakate, Sofie Mesens, Walter K. Kraft, Eugene E. Marcantonio
Publikováno v:
Clinical and Translational Science, Vol 13, Iss 3, Pp 462-472 (2020)
Ubrogepant is a novel, oral calcitonin gene‐related peptide (CGRP) receptor antagonist intended for the acute treatment of migraine attacks. Ubrogepant has a chemical structure distinct from previous small‐molecule CGRP receptor antagonists that
Externí odkaz:
https://doaj.org/article/574f65b94dbe404bae99bc9aaa2303f2
Autor:
Enriqueta Felip, Jianda Yuan, Lawrence Fong, Charu Aggarwal, Razvan Cristescu, Myung-Ju Ahn, Alexandra Snyder, Matthew Hellmann, Roy Herbst, Martin Gutierrez, Edward Garon, Jong-Seok Lee, Julie Kobie, Matthew Gubens, Daniel Shao Weng Tan, Joanne WY Chiu, James Chih-Hsin Yang, Giovanna Finocchiaro, Alexander Luft, Gregory Landers, Andrea Basso, Hua Ma, John Palcza
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/f606c751f88546b2b65dd38f5eef52da
Autor:
Peter Borchmann, Nathalie A. Johnson, David Lavie, Gareth Gregory, Alex F. Herrera, Leonard Minuk, Vladan Vucinic, Philippe Armand, Abraham Avigdor, Robin Gasiorowski, Yair Herishanu, Colm Keane, John Kuruvilla, John Palcza, Pallavi Pillai, Akash Nahar, John Timmerman
Publikováno v:
HemaSphere, Vol 6, Pp 28-28 (2022)
Externí odkaz:
https://doaj.org/article/dfe2fa3c30cf4a668d08ecad146c3a57
Autor:
Mark Forman, John Palcza, Jack Tseng, Julie A. Stone, Brittany Walker, Dennis Swearingen, Matthew D. Troyer, Marissa F. Dockendorf
Publikováno v:
Clinical and Translational Science, Vol 12, Iss 5, Pp 545-555 (2019)
β‐site amyloid precursor protein‐cleaving enzyme 1 (BACE1) is required for the production of β‐amyloid peptides, which are implicated in the etiology of Alzheimer's disease. The safety and pharmacokinetics of the BACE1 inhibitor verubecestat
Externí odkaz:
https://doaj.org/article/d5a82e2a471d464587738eee563b31d1
Autor:
Chi-Chung Li, John Palcza, Jialin Xu, Bob Thornton, Wendy Ankrom, Abhijeet Jakate, Eugene E Marcantonio
Publikováno v:
Cephalalgia Reports, Vol 3 (2020)
Background: Ubrogepant is a novel, oral calcitonin gene–related peptide receptor antagonist for acute treatment of migraine. This study evaluated potential drug–drug interactions between ubrogepant and an oral contraceptive containing ethinyl est
Externí odkaz:
https://doaj.org/article/e2fe76dd1b3e4b6ba5349c126f32253e
Autor:
Nathalie A. Johnson, David Lavie, Peter Borchmann, Gareth P. Gregory, Alex F. Herrera, Leonard Minuk, Vladan Vucinic, Philippe Armand, Abraham Avigdor, Robin Gasiorowski, Yair Herishanu, Colm Keane, John Kuruvilla, John Palcza, Pallavi Pillai, Akash Nahar, John Timmerman
Publikováno v:
Blood. 140:6540-6542
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b413ea75a8d36ebe9e8de9fbb1684f9d
https://doi.org/10.1182/blood-2022-166846
https://doi.org/10.1182/blood-2022-166846
Autor:
Roy Herbst, Wei-Sen Lam, Matthew Hellmann, Matthew Gubens, Charu Aggarwal, Daniel Shao Weng Tan, Enriqueta Felip, Joanne Chiu, Jong-Seok Lee, James Chih-Hsin Yang, Edward Garon, Giovanna Finocchiaro, Myung-Ju Ahn, Alexander Luft, Gregory Landers, Andrea Basso, Hua Ma, Julie Kobie, John Palcza, Razvan Cristescu, Lawrence Fong, Alexandra Snyder, Jianda Yuan, Martin Gutierrez
Publikováno v:
Regular and Young Investigator Award Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6914afa9aeac906b9e5e9ce6d58ce264
https://doi.org/10.1136/jitc-2022-sitc2022.0635
https://doi.org/10.1136/jitc-2022-sitc2022.0635
Autor:
Ednan K. Bajwa, Dawn Cislak, John Palcza, Hwa-ping Feng, Eric J. Messina, Tom Reynders, Jean-François Denef, Vasile Corcea, Eseng Lai, S. Aubrey Stoch
Publikováno v:
Respiratory medicine. 206
Novel therapeutics for pulmonary arterial hypertension (PAH) with improved safety/tolerability profiles are needed to address continued high rates of morbidity/mortality.This Phase 1 study evaluated efficacy/safety of inhaled single-dose MK-5475, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b613c915b63df1d18239ddc6ff9367fa
https://pubmed.ncbi.nlm.nih.gov/36521262
https://pubmed.ncbi.nlm.nih.gov/36521262
Autor:
Marissa F. Dockendorf, John A. Wagner, Wen Liu, John Palcza, Wendy Ankrom, Phung Bondiskey, Sofie Mesens, Deborah Panebianco, Eugene E. Marcantonio, Walter K. Kraft, Chi-Chung Li, Catherine Z. Matthews, Abhijeet Jakate, Tom Reynders
Publikováno v:
Clinical and Translational Science
Clinical and Translational Science, Vol 13, Iss 3, Pp 462-472 (2020)
Clinical and Translational Science, Vol 13, Iss 3, Pp 462-472 (2020)
Ubrogepant is a novel, oral calcitonin gene-related peptide (CGRP) receptor antagonist intended for the acute treatment of migraine attacks. Ubrogepant has a chemical structure distinct from previous small-molecule CGRP receptor antagonists that were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fe6646bbf37928500c03d56222b947c
https://doi.org/10.1111/cts.12728
https://doi.org/10.1111/cts.12728
Autor:
Sun Young Rha, Wilson H. Miller, María José de Miguel, Seock-Ah Im, Iwona Lugowska, Martin Wermke, Daisuke Kotani, Todd Michael Bauer, Atsuo Takashima, John Palcza, Marya F. Chaney, Konstantin Dobrenkov, Elena Garralda
Publikováno v:
Journal of Clinical Oncology. 41:394-394
394 Background: In the dose-confirmation phase of this multicohort trial (NCT02720068), the anti-LAG-3 antibody favezelimab had a manageable safety profile and promising antitumor activity in patients (pts) with advanced solid tumors, confirming prel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e0ed6652ca5051b01a8428a166fab73
https://doi.org/10.1200/jco.2023.41.4_suppl.394
https://doi.org/10.1200/jco.2023.41.4_suppl.394