Zobrazeno 1 - 10
of 130
pro vyhledávání: '"John, Novembre"'
Autor:
Nathaniel M. Pearson, John Novembre
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-7 (2024)
Abstract Early in the SARS-CoV2 pandemic, in this journal, Hou et al. (BMC Med 18:216, 2020) interpreted public genotype data, run through functional prediction tools, as suggesting that members of particular human populations carry potentially COVID
Externí odkaz:
https://doaj.org/article/94b08be8cfdd4a1cbaa754421d80e19a
Autor:
Chi-Chun Liu, David Witonsky, Anna Gosling, Ju Hyeon Lee, Harald Ringbauer, Richard Hagan, Nisha Patel, Raphaela Stahl, John Novembre, Mark Aldenderfer, Christina Warinner, Anna Di Rienzo, Choongwon Jeong
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Liu et al. report genome-wide data of 33 ancient individuals from the Himalayas, illuminating the deep genetic history of Tibetans and other Tibeto-Burman-speaking populations around the Tibetan Plateau in fine resolution.
Externí odkaz:
https://doaj.org/article/61122a4e43114b49978e97fe29f04c07
Autor:
Rasa A Muktupavela, Martin Petr, Laure Ségurel, Thorfinn Korneliussen, John Novembre, Fernando Racimo
Publikováno v:
eLife, Vol 11 (2022)
Ancient genome sequencing technologies now provide the opportunity to study natural selection in unprecedented detail. Rather than making inferences from indirect footprints left by selection in present-day genomes, we can directly observe whether a
Externí odkaz:
https://doaj.org/article/693db580758b4320a774b44451c74914
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Little is known about how human parental relatedness varied across ancient populations. Runs of homozygosity (ROH) in the offspring’s genome can give clues. Here, the authors present a method to identify ROH in ancient genomes and infer low rates o
Externí odkaz:
https://doaj.org/article/3c375c21a4024b49900aa78e6f0bd1ef
Autor:
Margaret C Steiner, John Novembre
Publikováno v:
PLoS Genetics, Vol 18, Iss 9, p e1010391 (2022)
Theoretical population genetics has long studied the arrival and geographic spread of adaptive variants through the analysis of mathematical models of dispersal and natural selection. These models take on a renewed interest in the context of the COVI
Externí odkaz:
https://doaj.org/article/8f0359212a814416b0aa21d61e5c0ffe
Autor:
Joseph H. Marcus, Cosimo Posth, Harald Ringbauer, Luca Lai, Robin Skeates, Carlo Sidore, Jessica Beckett, Anja Furtwängler, Anna Olivieri, Charleston W. K. Chiang, Hussein Al-Asadi, Kushal Dey, Tyler A. Joseph, Chi-Chun Liu, Clio Der Sarkissian, Rita Radzevičiūtė, Megan Michel, Maria Giuseppina Gradoli, Patrizia Marongiu, Salvatore Rubino, Vittorio Mazzarello, Daniela Rovina, Alessandra La Fragola, Rita Maria Serra, Pasquale Bandiera, Raffaella Bianucci, Elisa Pompianu, Clizia Murgia, Michele Guirguis, Rosana Pla Orquin, Noreen Tuross, Peter van Dommelen, Wolfgang Haak, David Reich, David Schlessinger, Francesco Cucca, Johannes Krause, John Novembre
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Ancient DNA analysis of early European farmers has found a high level of genetic affinity with present-day Sardinians. Here, the authors generate genome-wide capture data for 70 individuals from Sardinia spanning the Middle Neolithic to Medieval peri
Externí odkaz:
https://doaj.org/article/9ca429d9d3f34df58b2d938553624bbb
Publikováno v:
eLife, Vol 10 (2021)
Spatial population genetic data often exhibits ‘isolation-by-distance,’ where genetic similarity tends to decrease as individuals become more geographically distant. The rate at which genetic similarity decays with distance is often spatially het
Externí odkaz:
https://doaj.org/article/161324a62f814b56a6342a0bad1633b7
Publikováno v:
eLife, Vol 9 (2020)
A key challenge in human genetics is to understand the geographic distribution of human genetic variation. Often genetic variation is described by showing relationships among populations or individuals, drawing inferences over many variants. Here, we
Externí odkaz:
https://doaj.org/article/d513162c47f94ca3acd48509bf13abb8
Autor:
Aitor Serres-Armero, Inna S. Povolotskaya, Javier Quilez, Oscar Ramirez, Gabriel Santpere, Lukas F. K. Kuderna, Jessica Hernandez-Rodriguez, Marcos Fernandez-Callejo, Daniel Gomez-Sanchez, Adam H. Freedman, Zhenxin Fan, John Novembre, Arcadi Navarro, Adam Boyko, Robert Wayne, Carles Vilà, Belen Lorente-Galdos, Tomas Marques-Bonet
Publikováno v:
BMC Genomics, Vol 18, Iss 1, Pp 1-15 (2017)
Abstract Background Whole genome re-sequencing data from dogs and wolves are now commonly used to study how natural and artificial selection have shaped the patterns of genetic diversity. Single nucleotide polymorphisms, microsatellites and variants
Externí odkaz:
https://doaj.org/article/02734fe3325045ee863c35aca91a8746
Publikováno v:
GENETICS. 224
In studying allele-frequency variation across populations, it is often convenient to classify an allelic type as “rare,” with nonzero frequency less than or equal to a specified threshold, “common,” with a frequency above the threshold, or en