Zobrazeno 1 - 10
of 239
pro vyhledávání: '"John, Myburgh"'
Autor:
Brittany Dennis, Adam Deane, François Lauzier, Nicole Zytaruk, Miranda Hardie, Naomi Hammond, Simon Finfer, Yaseen Arabi, John Marshall, Lois Saunders, Diane Heels-Ansdell, John Myburgh, Serena Knowles, John Muscedere, Marlies Ostermann, Dorrilyn Rajbhandari, Shane English, Karlo Matic, Bala Venkatesh, Abdulrahman Al Fares, Gordon Guyatt, Waleed Alhazzani, Hassan Mumtaz, Alexis Poole, Feng Xie, Lehana Thabane, Richard Hall, Deborah Cook
Publikováno v:
BMC Medical Research Methodology, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background During the COVID-19 pandemic, many intensive care units (ICUs) halted research to focus on COVID-19-specific studies. Objective To describe the conduct of an international randomized trial of stress ulcer prophylaxis (Re-Evaluatin
Externí odkaz:
https://doaj.org/article/bd70c4426fae4e6585d45506d3cf8e59
Autor:
Nazima Pathan, Kerry Woolfall, Mariana Popa, Gema Milla de la Fuente, Paloma Ferrando-Vivas, Alanna Brown, Theodore Gouliouris, Lyvonne N. Tume, Robert Shulman, Brian H. Cuthbertson, Isobel Sale, Richard G. Feltbower, John Myburgh, John Pappachan, David Harrison, Paul Mouncey, Kathryn Rowan, the PICNIC study investigators
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Healthcare-associated infections (HCAIs) are a major cause of morbidity and mortality in critically ill children. Data from adult studies suggest Selective Decontamination of the Digestive tract (SDD) may reduce the incidence of HCAIs and im
Externí odkaz:
https://doaj.org/article/8eeebe4fea0f416ebb3f90d92544a666
Autor:
Diane Heels-Ansdell, Laurent Billot, Lehana Thabane, Waleed Alhazzani, Adam Deane, Gordon Guyatt, Simon Finfer, François Lauzier, John Myburgh, Paul Young, Yaseen Arabi, John Marshall, Shane English, John Muscedere, Marlies Ostermann, Bala Venkatesh, Nicole Zytaruk, Miranda Hardie, Naomi Hammond, Serena Knowles, Lois Saunders, Alexis Poole, Abdulrahman Al-Fares, Feng Xie, Richard Hall, Deborah Cook
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-9 (2023)
Abstract Background The REVISE (Re-Evaluating the Inhibition of Stress Erosions in the ICU) trial will evaluate the impact of the proton pump inhibitor pantoprazole compared to placebo in invasively ventilated critically ill patients. Objective To ou
Externí odkaz:
https://doaj.org/article/f43b3946a0134c0d91e8980efc07406e
Autor:
Alanna Brown, Paloma Ferrando-Vivas, Mariana Popa, Gema Milla de la Fuente, John Pappachan, Brian H Cuthbertson, Laura Drikite, Richard Feltbower, Theodore Gouliouris, Isobel Sale, Robert Shulman, Lyvonne N Tume, John Myburgh, Kerry Woolfall, David A Harrison, Paul R Mouncey, Kathryn Rowan, Nazima Pathan
Publikováno v:
Health Technology Assessment, Vol 28, Iss 08 (2024)
Background Healthcare-associated infections are a major cause of morbidity and mortality in critically ill children. In adults, data suggest the use of selective decontamination of the digestive tract may reduce the incidence of healthcare-associated
Externí odkaz:
https://doaj.org/article/1d17afa114d54d8a8b7f5dcc0f62c0fc
Autor:
Brittany B. Dennis, Lehana Thabane, Diane Heels-Ansdell, Joanna C. Dionne, Alexandra Binnie, Jennifer Tsang, Gordon Guyatt, Aijaz Ahmed, François Lauzier, Adam Deane, Yaseen Arabi, John Marshall, Nicole Zytaruk, Lois Saunders, Simon Finfer, John Myburgh, John Muscedere, Shane English, Marlies Ostermann, Miranda Hardie, Serena Knowles, Deborah Cook, For the REVISE Investigators the Canadian Critical Care Trials Group
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-10 (2023)
Abstract Background Critically ill patients commonly receive proton pump inhibitors (PPIs) to prevent gastrointestinal (GI) bleeding from stress-induced ulceration. Despite widespread use in the intensive care unit (ICU), observational data suggest t
Externí odkaz:
https://doaj.org/article/bdfab15867474f8e8cd4f0e5dcbdda5e
Autor:
Emily R. Daubney, BE/BSc, Shannon D’Urso, BAdvSc (Hons), Gabriel Cuellar-Partida, PhD, Dorrilyn Rajbhandari, RN, Elizabeth Peach, MS, Erika de Guzman, BBSc, Colin McArthur, MD, Andrew Rhodes, MD, Jason Meyer, RN, Simon Finfer, MD, John Myburgh, MD, PhD, Jeremy Cohen, MD, PhD, Horst Joachim Schirra, PhD, Balasubramanian Venkatesh, MD, David M. Evans, PhD
Publikováno v:
Critical Care Explorations, Vol 6, Iss 1, p e1030 (2024)
OBJECTIVES:. We sought to assess whether genetic associations with metabolite concentrations in septic shock patients could be used to identify pathways of potential importance for understanding sepsis pathophysiology. DESIGN:. Retrospective multicen
Externí odkaz:
https://doaj.org/article/158ad5eba31446ff8c699b5134a934d5
Autor:
Lehana Thabane, Gordon Guyatt, Diane Heels-Ansdell, Deborah J Cook, Yaseen Arabi, John Muscedere, Paul Young, Feng Xie, François Lauzier, Laurent Billot, Waleed Alhazzani, Marlies Ostermann, Shane English, Daniel Johnson, John C Marshall, Nicole Zytaruk, Balasubramanian Venkatesh, Simon Finfer, John Myburgh, R Hall, Mobeen Iqbal, Abdulrahman A Al-Fares, Gilmar Reis, Alexis Poole, Adam M Deane, Marianne J Chapman, Dorrilyn Rajbhandari, Naomi E Hammond, Serena Knowles, Miranda Hardie, Lois Saunders
Publikováno v:
BMJ Open, Vol 13, Iss 11 (2023)
Introduction The Re-Evaluating the Inhibition of Stress Erosions (REVISE) Trial aims to determine the impact of the proton pump inhibitor pantoprazole compared with placebo on clinically important upper gastrointestinal (GI) bleeding in the intensive
Externí odkaz:
https://doaj.org/article/6494babd732e4acaa7d4de624fcce7da
Autor:
Yunlin Feng, Qiang Li, Simon Finfer, John Myburgh, Rinaldo Bellomo, Vlado Perkovic, Meg Jardine, Amanda Y. Wang, Martin Gallagher
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundTo develop a risk prediction model for the occurrence of severe acute kidney injury (AKI) in intensive care unit (ICU) patients receiving fluid resuscitation.MethodsWe conducted a secondary analysis of the Crystalloid vs. Hydroxyethyl Starc
Externí odkaz:
https://doaj.org/article/29d788c5e0c14ff0bcd674bbd6a0439b
Autor:
Kerry Woolfall, Nazima Pathan, Lyvonne N Tume, John Pappachan, Kathryn M Rowan, Richard Feltbower, Mariana Popa, David A Harrison, Paloma Ferrando, Brian Cuthbertson, Laura Drikite, Paul R Mouncey, John Myburgh, Theodore Gouliouris, Alanna Brown, Gema Milla de la Fuente, Isobel Sale, Robert Shulman
Publikováno v:
BMJ Open, Vol 12, Iss 3 (2022)
Introduction Healthcare-associated infections (HCAIs) are a major cause of morbidity and mortality in critically ill children. In critically ill adults, there are data that suggest the use of Selective Decontamination of the Digestive tract (SDD), al
Externí odkaz:
https://doaj.org/article/eb6cf39d885a47b6bf21140e4f67f2f6
Autor:
Mahesh Ramanan, Laurent Billot, Dorrilyn Rajbhandari, John Myburgh, Simon Finfer, Rinaldo Bellomo, Balasubramanian Venkatesh
Publikováno v:
Trials, Vol 21, Iss 1, Pp 1-8 (2020)
Abstract Background Randomised controlled trials (RCT) may be hindered by slow recruitment rates, particularly in critically ill patients. While statistical models to predict recruitment rates have been described, no systematic assessment has been co
Externí odkaz:
https://doaj.org/article/f55b8e4af73e45b6965737bb52f0c669