Zobrazeno 1 - 8
of 8
pro vyhledávání: '"John, Miglietta"'
Autor:
Rebecca Ebenhoch, Abbas Akhdar, Marc R. Reboll, Mortimer Korf-Klingebiel, Priyanka Gupta, Julie Armstrong, Yining Huang, Lee Frego, Irina Rybina, John Miglietta, Anton Pekcec, Kai C. Wollert, Herbert Nar
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Myeloid-derived growth factor (MYDGF) is an angiogenic growth factor with therapeutic potential for ischemic tissue repair and the receptor is still unknown. Here the authors present the crystal structure of human MYDGF and identify its functional ep
Externí odkaz:
https://doaj.org/article/7aa1821abf454c21a63dba52daa89da7
Autor:
Peng, Sun, Christina S, Bartlett, Chao, Zheng, Tammy, Bigwarfe, Joshuaine M, Grant, Margit, MacDougall, Valentina, Berger, Steven, Kerr, Hu Sheng, Qian, Mark, McHugh, Hongxing, Chen, Xiaomei, Zhang, Miranda L, Carpenter, Heather N, Robinson, John, Miglietta, Thorsten, Lamla, Ryan M, Fryer
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 382:266-276
Diabetic nephropathy is a leading cause of end-stage renal disease, characterized by endothelial dysfunction and a compromised glomerular permeability barrier. Dysregulation of the angiopoietin 1 (ANGPT1)/angiopoietin 2 (ANGPT2) signaling axis is imp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::374bd8d82a45deba15901277988434a3
https://doi.org/10.1124/jpet.121.001067
https://doi.org/10.1124/jpet.121.001067
Autor:
Tibor Kempf, Anton Pekcec, John Miglietta, Evangelos Giannitsis, Christian Widera, Johann Bauersachs, Marc R. Reboll, Felix Polten, Kerstin Bethmann, Andreas Pich, Kai C. Wollert, Jochen Tillmanns, Priyanka Gupta
Publikováno v:
Analytical Chemistry. 91:1302-1308
Myeloid-derived growth factor (MYDGF in humans, Mydgf in mice) is a secreted protein with previously unknown biological functions. In a recent study, Mydgf was shown to mediate cardiac repair after acute myocardial infarction (MI) in mice. Lack of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::063f72b89dff7be46c748738d3f6530f
https://doi.org/10.1021/acs.analchem.8b03041
https://doi.org/10.1021/acs.analchem.8b03041
Autor:
Erica Waltz, Rachel Kroe-Barrett, Tammy Bigwarfe, Sarah Low, John Miglietta, Hua Li, Cynthia Hess Kenny, Maria Myzithras, Jennifer Ahlberg, Irina Rybina
Publikováno v:
Bioanalysis. 10:397-406
Aim: The fully automated microfluidics-based Gyrolab is a popular instrument for the bioanalysis of protein therapeutics; requiring minimal sample and reagent volumes. Gyros offers affinity software for determining binding affinity in solution using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d754d041ec368ad7e12747657cf77d90
https://doi.org/10.4155/bio-2017-0251
https://doi.org/10.4155/bio-2017-0251
Autor:
Yining Huang, Irina Rybina, Rebecca Ebenhoch, John Miglietta, Anton Pekcec, Abbas Akhdar, Mortimer Korf-Klingebiel, Kai C. Wollert, Julie Armstrong, Marc R. Reboll, Herbert Nar, Priyanka Gupta, Lee Frego
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Myeloid-derived growth factor (MYDGF) is a paracrine-acting protein that is produced by bone marrow-derived monocytes and macrophages to protect and repair the heart after myocardial infarction (MI). This effect can be used for the development of pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37f4115844ff9a9ccb01f1e2b6a2cf09
https://pubmed.ncbi.nlm.nih.gov/31772377
https://pubmed.ncbi.nlm.nih.gov/31772377
Publikováno v:
Drug Discovery Today: Therapeutic Strategies. 8:109-116
The approach of drug repositioning is an important consideration for any life science organization. By using knowledge-driven systems in the form of large data stores and applying rational in silico experimental design, researchers have generated wor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54cfb309e79fab52308f91eae5af95c7
https://doi.org/10.1016/j.ddstr.2011.06.004
https://doi.org/10.1016/j.ddstr.2011.06.004
Publikováno v:
Medicinal research reviews. 12(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a07ae6b4d9fdb9a10749135adb151d42
https://pubmed.ncbi.nlm.nih.gov/1371177
https://pubmed.ncbi.nlm.nih.gov/1371177
Autor:
Peter M. Grob, Anthony Shrutkowski, John Miglietta, Mark T. Skoog, Elizabeth B. Kopp, Cheng-Kon Shih
Steady state kinetics and inhibition by a dipyridodiazepinone of the reverse transcriptase from human immunodeficiency virus type 1 (HIV) were studied using a heteropolymeric RNA template with a sequence from the authentic initiation site on the HIV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad8394d81a07f3db529583fced7908ea
https://europepmc.org/articles/PMC328267/
https://europepmc.org/articles/PMC328267/
