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pro vyhledávání: '"John, Michael S."'
Publikováno v:
In Clinical Immunology February 2022 235
Akademický článek
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Autor:
John Michael S. Sanchez, Daniel J. Doty, Ana Beatriz DePaula-Silva, D. Garrett Brown, Rickesha Bell, Kendra A. Klag, Amanda Truong, Jane E. Libbey, June L. Round, Robert S. Fujinami
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-14 (2020)
Abstract Background Multiple sclerosis (MS) is an inflammatory demyelinating disease that affects 2.5 million people worldwide. Growing evidence suggests that perturbation of the gut microbiota, the dense collection of microorganisms that colonize th
Externí odkaz:
https://doaj.org/article/8532539cee2a41329b1d2acb156ebb93
Autor:
John Michael S. Sanchez, Ana Beatriz DePaula-Silva, Daniel J. Doty, Tyler J. Hanak, Amanda Truong, Jane E. Libbey, Robert S. Fujinami
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Viral encephalitis is a major cause of morbidity and mortality, but the manifestation of disease varies greatly between individuals even in response to the same virus. Microglia are professional antigen presenting cells that reside in the central ner
Externí odkaz:
https://doaj.org/article/2590a186d9da4d6a9985d993cb85aca3
Autor:
Ana Beatriz DePaula-Silva, Carlos Gorbea, Daniel J. Doty, Jane E. Libbey, John Michael S. Sanchez, Tyler J. Hanak, Demián Cazalla, Robert S. Fujinami
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-20 (2019)
Abstract Background In the healthy central nervous system (CNS), microglia are found in a homeostatic state and peripheral macrophages are absent from the brain. Microglia play key roles in maintaining CNS homeostasis and acting as first responders t
Externí odkaz:
https://doaj.org/article/5802daf8a26b4bbea220e0fa04954ff7
Autor:
John Michael S. Sanchez, J. Scott McNally, Melissa M. Cortez, James Hemp, Laura A. Pace, Stacey L. Clardy
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
The central nervous system (CNS) is an important regulator of the gastrointestinal tract, and CNS dysfunction can result in significant and disabling gastrointestinal symptom manifestation. For patients with neuroimmunologic and neuroinflammatory con
Externí odkaz:
https://doaj.org/article/594310e346cf4e73ab8cf6cf4bf407e8
Autor:
Martin McMahon, Shannon J. Odelberg, Kendall J. Blumer, Michael D. Onken, Phaedra C. Ghazi, Donghan Shin, Jackson R. Richards, Conan G. Kinsey, Kali J. Dale, John Michael S. Sanchez, Michael T. Scherzer, Jae Hyuk Yoo, Amanda Truong
Galpha and MEK1/2 inhibition in combination with Baf A1 and CQ in MP41 cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b62cecbbd58a39469827f70b19c5083
https://doi.org/10.1158/1078-0432.22476333
https://doi.org/10.1158/1078-0432.22476333
Autor:
Martin McMahon, Shannon J. Odelberg, Kendall J. Blumer, Michael D. Onken, Phaedra C. Ghazi, Donghan Shin, Jackson R. Richards, Conan G. Kinsey, Kali J. Dale, John Michael S. Sanchez, Michael T. Scherzer, Jae Hyuk Yoo, Amanda Truong
Supplementary Materials and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::435ae12189801037b26a40108d7bc033
https://doi.org/10.1158/1078-0432.22476306.v1
https://doi.org/10.1158/1078-0432.22476306.v1
Autor:
Martin McMahon, Shannon J. Odelberg, Kendall J. Blumer, Michael D. Onken, Phaedra C. Ghazi, Donghan Shin, Jackson R. Richards, Conan G. Kinsey, Kali J. Dale, John Michael S. Sanchez, Michael T. Scherzer, Jae Hyuk Yoo, Amanda Truong
Purpose:Mutational activation of GNAQ or GNA11 (GNAQ/11), detected in >90% of uveal melanomas, leads to constitutive activation of oncogenic pathways, including MAPK and YAP. To date, chemo- or pathway-targeted therapies, either alone or in combinati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92e174ef9a4f492cc311540af6167f38
https://doi.org/10.1158/1078-0432.c.6529368
https://doi.org/10.1158/1078-0432.c.6529368
Autor:
Jackson R. Richards, Michael D. Onken, Kali J. Dale, Phaedra Ghazi, Jae Hyuk Yoo, John Michael S. Sanchez, Kendall J. Blumer, Martin McMahon, Shannon J. Odelberg, Amanda Truong, Donghan Shin, Michael T. Scherzer, Conan G. Kinsey
Publikováno v:
Clin Cancer Res
Purpose:Mutational activation of GNAQ or GNA11 (GNAQ/11), detected in >90% of uveal melanomas, leads to constitutive activation of oncogenic pathways, including MAPK and YAP. To date, chemo- or pathway-targeted therapies, either alone or in combinati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cc960c5575d33f0972043247f372086
https://doi.org/10.1158/1078-0432.ccr-20-1675
https://doi.org/10.1158/1078-0432.ccr-20-1675