Zobrazeno 1 - 10
of 33
pro vyhledávání: '"John, Mellors"'
Autor:
Marc-Kendy Paul, Manish Choudhary, Amy Heaps, Rinki Deo, Daniela Moisi, Kelley Gordon, John Mellors, Carlee Moser, Paul Klekotka, Alan Landay, Judith Currier, Joseph Eron, Kara Chew, Davey Smith, Scott Sieg, Urvi Parikh, Jonathan Li
Publikováno v:
Pathogens and Immunity, Vol 9, Iss 2 (2024)
Background: Anti-SARS-CoV-2 monoclonal antibodies (mAbs) have played a key role as an antiviral against SARS-CoV-2, but there is a potential for resistance to develop. The interplay between host antibody responses and the development of monoclonal an
Externí odkaz:
https://doaj.org/article/bdccb63bddb5442fabd3c42a04dba847
Autor:
Urvi Parikh, Amy Heaps, Daniela Moisi, Kelley Gordon, John Mellors, Manish Choudhary, Rinki Deo, Carlee Moser, Paul Klekotka, Alan Landay, Judith Currier, Joseph Eron, Kara Chew, Davey Smith, Jonathan Li, Scott Sieg, ACTIV-2/A5401 Study Team
Publikováno v:
Pathogens and Immunity, Vol 9, Iss 2 (2024)
Background: Assessing the breadth and duration of antigen-specific binding antibodies provides valuable information for evaluating interventions to treat or prevent SARS-CoV-2 infection. Multiplex immunoassays are a convenient method for rapid measur
Externí odkaz:
https://doaj.org/article/370dd23cdf414e01a8ece2d10d410282
Autor:
Eva M. Stevenson, Adam R. Ward, Thomas R. Dilling, John K. Bui, John Mellors, Rajesh Gandhi, Deborah McMahon, Joseph Eron, Ronald Bosch, Christina Lalama, Joshua Cyktor, Brad Jones
Publikováno v:
Journal of Virus Eradication, Vol 5, Iss , Pp 32- (2019)
Externí odkaz:
https://doaj.org/article/3c238e6e2bb54924bac5f257d41ee792
Autor:
Mark A. Marzinke, Jessica M. Fogel, Zhe Wang, Estelle Piwowar-Manning, Ryan Kofron, Amber Moser, Pradip Bhandari, Ryann Gollings, Lane R. Bushman, Lei Weng, Elias K. Halvas, John Mellors, Peter L. Anderson, Deborah Persaud, Craig W. Hendrix, Marybeth McCauley, Alex R. Rinehart, Marty St Clair, Susan L. Ford, James F. Rooney, Adeola Adeyeye, Suwat Chariyalertsak, Kenneth Mayer, Roberto C. Arduino, Myron S. Cohen, Beatriz Grinsztejn, Brett Hanscom, Raphael J. Landovitz, Susan H. Eshleman
Publikováno v:
Antimicrobial Agents and Chemotherapy. 67
HPTN 083 demonstrated that injectable cabotegravir (CAB) was superior to oral tenofovir disoproxil fumarate-emtricitabine (TDF-FTC) for HIV prevention in cisgender men and transgender women who have sex with men. We previously analyzed 58 infections
Autor:
Priscila M S Castanha, Dylan J Tuttle, Georgios D Kitsios, Jana L Jacobs, Ulisses Braga-Neto, Matthew Duespohl, Sanjay Rathod, Michelle M Marti, Sarah Wheeler, Asma Naqvi, Brittany Staines, John Mellors, Alison Morris, Bryan J McVerry, Faraaz Shah, Caitlin Schaefer, Bernard J C Macatangay, Barbara Methe, Christian A Fernandez, Simon M Barratt-Boyes, Donald Burke, Ernesto T A Marques
Publikováno v:
The Journal of Infectious Diseases. 226:766-777
Background Excessive complement activation has been implicated in the pathogenesis of coronavirus disease 2019 (COVID-19), but the mechanisms leading to this response remain unclear. Methods We measured plasma levels of key complement markers, severe
Autor:
Michael Lu, Callie Drohan, William Bain, Faraaz A. Shah, Matthew Bittner, John Evankovich, Niall Prendergast, Matthew Hensley, Tomeka Suber, Meghan Fitzpatrick, Raj Ramanan, Holt Murray, Caitlin Schaefer, Shulin Qin, Xiaohong Wang, Yingze Zhang, Seyed M. Nouraie, Heather Gentry, Cathy Kessinger, Asha Patel, Bernard J. Macatangay, Jana Jacobs, John Mellors, Janet S. Lee, Prabir Ray, Anuradha Ray, Barbara Methé, Alison Morris, Bryan J. McVerry, Georgios D. Kitsios
Publikováno v:
medRxiv
PurposeEnhanced understanding of the dynamic changes in the dysregulated inflammatory response in COVID-19 may help improve patient selection and timing for immunomodulatory therapies.MethodsWe enrolled 323 COVID-19 inpatients on different levels of
Autor:
John, Steytler, Charles, Craig, Elna, van der Ryst, Ben, Van Baelen, Jeremy, Nuttall, Neliëtte, van Niekerk, John, Mellors, Urvi, Parikh, Carole, Wallis
Publikováno v:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
The Ring Study, a 2:1 randomized, double-blind, placebo-controlled Phase III trial, demonstrated 35.1% HIV-1 infection risk reduction among participants using the Dapivirine Vaginal Ring-004 (DVR). An open-label extension trial, DREAM, approximated a
Autor:
John, Steytler, Elna, van der Ryst, Charles, Craig, Ben, Van Baelen, Jeremy, Nuttall, Neliëtte, van Niekerk, John, Mellors, Urvi, Parikh, Carole, Wallis
Publikováno v:
Clin Infect Dis
BACKGROUND: Participants with human immunodeficiency virus (HIV) seroconversion in The Ring Study, a phase 3 trial of dapivirine vaginal ring (DVR), or in the open-label extension trial dapivirine ring extended access and monitoring (DREAM) were offe
Autor:
Susan H Eshleman, Jessica M Fogel, Estelle Piwowar-Manning, Gordon Chau, Vanessa Cummings, Yaw Agyei, Paul Richardson, Philip Sullivan, Casey D Haines, Lane R Bushman, Christos Petropoulos, Deborah Persaud, Ryan Kofron, Craig W Hendrix, Peter L Anderson, Jennifer Farrior, John Mellors, Adeola Adeyeye, Alex Rinehart, Marty St Clair, Susan Ford, James F Rooney, Carrie-Anne Mathew, Portia Hunidzarira, Elizabeth Spooner, Juliet Mpendo, Gonasagrie Nair, Myron S Cohen, James P Hughes, Mina Hosseinipour, Brett Hanscom, Sinead Delany-Moretlwe, Mark A Marzinke
Publikováno v:
J Infect Dis
Background HIV Prevention Trials Network 084 demonstrated that long-acting injectable cabotegravir (CAB) was superior to daily oral tenofovir (TFV) disoproxil fumarate (TDF)/emtricitabine (FTC) for preventing human immunodeficiency virus (HIV) infect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53e0453d61c4e959ab64f8a8504d7157
https://europepmc.org/articles/PMC9113509/
https://europepmc.org/articles/PMC9113509/
Publikováno v:
Open Forum Infectious Diseases
Background Remote telemedicine ID consults (Tele-ID) appear to be effective for inpatients at community hospitals. Tele-ID is not used at academic medical centers (AMCs) because of the availability of onsite ID physicians. During the COVID-19 pandemi