Zobrazeno 1 - 10
of 144
pro vyhledávání: '"John, Lusingu"'
Autor:
Yolanda Guerra Mendoza, Elodie Garric, Amanda Leach, Marc Lievens, Opokua Ofori-Anyinam, Jean-Yves Pirçon, Jens-Ulrich Stegmann, Pascale Vandoolaeghe, Lucas Otieno, Walter Otieno, Seth Owusu-Agyei, Jahit Sacarlal, Nahya Salim Masoud, Hermann Sorgho, Marcel Tanner, Halidou Tinto, Innocent Valea, Ali Takadir Mtoro, Patricia Njuguna, Martina Oneko, Godfrey Allan Otieno, Kephas Otieno, Samwel Gesase, Mary J Hamel, Irving Hoffman, Seyram Kaali, Portia Kamthunzi, Peter Kremsner, Miguel Lanaspa, Bertrand Lell, John Lusingu, Anangisye Malabeja, Pedro Aide, Pauline Akoo, Daniel Ansong, Kwaku Poku Asante, James A Berkley, Samuel Adjei, Tsiri Agbenyega, Selidji Todagbe Agnandji, Lode Schuerman
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 15, Iss 10, Pp 2386-2398 (2019)
A phase III, double-blind, randomized, controlled trial (NCT00866619) in sub-Saharan Africa showed RTS,S/AS01 vaccine efficacy against malaria. We now present in-depth safety results from this study. 8922 children (enrolled at 5–17 months) and 6537
Externí odkaz:
https://doaj.org/article/32543b5d892e42548e7e71deabcf0cf8
Autor:
Gédéon Prince Manouana, Eva Lorenz, Mirabeau Mbong Ngwese, Paul Alvyn Nguema Moure, Oumou Maiga Ascofaré, Charity Wiafe Akenten, John Amuasi, Njari Rakotozandrindrainy, Raphael Rakotozandrindrainy, Joyce Mbwana, John Lusingu, Natalie Byrne, Sophia Melhem, Jeannot Frejus Zinsou, Roméo Bayodé Adegbite, Benedikt Hogan, Doris Winter, Jurgen May, Peter Gottfried Kremsner, Steffen Borrmann, Daniel Eibach, Ayola Akim Adegnika
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 7, p e0008448 (2020)
BackgroundCryptosporidium is a protozoan parasite that causes mild to severe diarrhoeal disease in humans. To date, several commercial companies have developed rapid immunoassays for the detection of Cryptosporidium infection. However, the challenge
Externí odkaz:
https://doaj.org/article/d8d3df87bcda4d09bb6598f72e32b512
Autor:
Samuel Cordey, Florian Laubscher, Mary-Anne Hartley, Thomas Junier, Francisco J. Pérez-Rodriguez, Kristina Keitel, Gael Vieille, Josephine Samaka, Tarsis Mlaganile, Frank Kagoro, Noémie Boillat-Blanco, Zainab Mbarack, Mylène Docquier, Francisco Brito, Daniel Eibach, Jürgen May, Peter Sothmann, Cassandra Aldrich, John Lusingu, Caroline Tapparel, Valérie D’Acremont, Laurent Kaiser
Publikováno v:
Emerging Microbes and Infections, Vol 8, Iss 1, Pp 613-623 (2019)
ABSTRACTFever is the leading cause of paediatric outpatient consultations in Sub-Saharan Africa. Although most are suspected to be of viral origin, a putative causative pathogen is not identified in over a quarter of these febrile episodes. Using a d
Externí odkaz:
https://doaj.org/article/a5be99b5fe8f4a26a02b3af3ed43f439
Autor:
Chris Drakeley, Salim Abdulla, Selidji Todagbe Agnandji, José Francisco Fernandes, Peter Kremsner, Bertrand Lell, Ludovic Mewono, Bache Emmanuel Bache, Michael Gabriel Mihayo, Omar Juma, Marcel Tanner, Marc Christian Tahita, Halidou Tinto, Salou Diallo, Palpouguini Lompo, Umberto D’Alessandro, Bernhards Ogutu, Lucas Otieno, Solomon Otieno, Walter Otieno, Janet Oyieko, Kwaku Poku Asante, Dominic Bon-Ereme Dery, George Adjei, Elisha Adeniji, Dorcas Atibilla, Seth Owusu-Agyei, Brian Greenwood, Samwel Gesase, John Lusingu, Coline Mahende, Robert Mongi, Method Segeja, Samuel Adjei, Tsiri Agbenyega, Alex Agyekum, Daniel Ansong, John Tanko Bawa, Harry Owusu Boateng, Léonard Dandalo, Veronica Escamilla, Irving Hoffman, Peter Maenje, Francis Martinson, Terrell Carter, Didier Leboulleux, David C. Kaslow, Effua Usuf, Jean-Yves Pirçon, Edith Roset Bahmanyar
Publikováno v:
Malaria Journal, Vol 16, Iss 1, Pp 1-15 (2017)
Abstract Background Plasmodium falciparum prevalence (PfPR) is a widely used metric for assessing malaria transmission intensity. This study was carried out concurrently with the RTS,S/AS01 candidate malaria vaccine Phase III trial and estimated PfPR
Externí odkaz:
https://doaj.org/article/6e058e429cf64226b67c39b4bafbf55f
Autor:
Kevin Croke, Deus S. Ishengoma, Filbert Francis, Julie Makani, Mathias L. Kamugisha, John Lusingu, Martha Lemnge, Horacio Larreguy, Günther Fink, Bruno P. Mmbando
Publikováno v:
BMC Infectious Diseases, Vol 17, Iss 1, Pp 1-6 (2017)
Abstract Background Sickle Cell Trait (SCT) has been shown to be protective against malaria. A growing literature suggests that malaria exposure can reduce educational attainment. This study assessed the relationship and interactions between malaria,
Externí odkaz:
https://doaj.org/article/99a9e1ce84964a0ba435c7177d067c4b
Autor:
Fergal Duffy, Maria Bernabeu, Prasad H. Babar, Anne Kessler, Christian W. Wang, Marina Vaz, Laura Chery, Wilson L. Mandala, Stephen J. Rogerson, Terrie E. Taylor, Karl B. Seydel, Thomas Lavstsen, Edwin Gomes, Kami Kim, John Lusingu, Pradipsinh K. Rathod, John D. Aitchison, Joseph D. Smith
Publikováno v:
mBio, Vol 10, Iss 2 (2019)
ABSTRACT The clinical presentation of severe Plasmodium falciparum malaria differs between children and adults, but the mechanistic basis for this remains unclear. Contributing factors to disease severity include total parasite biomass and the divers
Externí odkaz:
https://doaj.org/article/d4ebf5cd94fa48a89e98ace612f93095
Autor:
Mireia Valles-Colomer, Aitor Blanco-Míguez, Paolo Manghi, Francesco Asnicar, Leonard Dubois, Davide Golzato, Federica Armanini, Fabio Cumbo, Kun D. Huang, Serena Manara, Giulia Masetti, Federica Pinto, Elisa Piperni, Michal Punčochář, Liviana Ricci, Moreno Zolfo, Olivia Farrant, Adriana Goncalves, Marta Selma-Royo, Ana G. Binetti, Jimmy E. Becerra, Bei Han, John Lusingu, John Amuasi, Loredana Amoroso, Alessia Visconti, Claire M. Steves, Mario Falchi, Michele Filosi, Adrian Tett, Anna Last, Qian Xu, Nan Qin, Huanlong Qin, Jürgen May, Daniel Eibach, Maria Valeria Corrias, Mirco Ponzoni, Edoardo Pasolli, Tim D. Spector, Enrico Domenici, Maria Carmen Collado, Nicola Segata
The human microbiome is an integral component of the human body and a co-determinant of several health conditions1,2. However, the extent to which interpersonal relations shape the individual genetic makeup of the microbiome and its transmission with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7438e9a3141ff49440bb8cbdbd0ba4e
https://www.nature.com/articles/s41586-022-05620-1#citeas
https://www.nature.com/articles/s41586-022-05620-1#citeas
Autor:
John Lusingu, Susana Campino, Michael Alifrangis, Michael Theisen, Ole Lund, Tine Kliim Nydahl, Marina Crespo Bravo, Cally Roper, Subhash C. Singh, Helle H Hansson, Susheel K. Singh, Christian W. Wang, Samuel Yao Ahorhorlu, Manoj K. Das, Magatte Ndiaye
Publikováno v:
Nydahl, T K, Ahorhorlu, S Y, Ndiaye, M, Das, M K, Hansson, H, Bravo, M C, Wang, C W, Lusingu, J, Theisen, M, Singh, S K, Singh, S, Campino, S, Lund, O, Roper, C & Alifrangis, M 2021, ' Identification of single-nucleotide polymorphisms in the mitochondrial genome and kelch 13 gene of Plasmodium falciparum in different geographical populations ', American Journal of Tropical Medicine and Hygiene, vol. 105, no. 4, pp. 1085-1092 . https://doi.org/10.4269/ajtmh.21-0320
Am J Trop Med Hyg
Am J Trop Med Hyg
The emergence of artemisinin-resistant Plasmodium falciparum parasites in Southeast Asia threatens malaria control and elimination. The interconnectedness of parasite populations may be essential to monitor the spread of resistance. Combining a publi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c872d38b63c4550c087abcb96893fa0e
https://doi.org/10.4269/ajtmh.21-0320
https://doi.org/10.4269/ajtmh.21-0320
Autor:
Michael Alifrangis, Edwin Liheluka, Paul M. Hayuma, Gerald Misinzo, Daniel T. R. Minja, Christian W. Wang, Vito Baraka, John Lusingu, Rashid A. Madebe
Publikováno v:
Malaria Journal, Vol 20, Iss 1, Pp 1-9 (2021)
Malaria Journal
Hayuma, P M, Wang, C W, Liheluka, E, Baraka, V, Madebe, R A, Minja, D T R, Misinzo, G, Alifrangis, M & Lusingu, J P A 2021, ' Prevalence of asymptomatic malaria, submicroscopic parasitaemia and anaemia in Korogwe District, north-eastern Tanzania ', Malaria Journal, vol. 20, 424 . https://doi.org/10.1186/s12936-021-03952-3
Malaria Journal
Hayuma, P M, Wang, C W, Liheluka, E, Baraka, V, Madebe, R A, Minja, D T R, Misinzo, G, Alifrangis, M & Lusingu, J P A 2021, ' Prevalence of asymptomatic malaria, submicroscopic parasitaemia and anaemia in Korogwe District, north-eastern Tanzania ', Malaria Journal, vol. 20, 424 . https://doi.org/10.1186/s12936-021-03952-3
Background Asymptomatic malaria infections largely remain undetected and act as a reservoir for continuous transmission. The study assessed the prevalence of submicroscopic asymptomatic malaria infections and anaemia in two rural low (300 m above sea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7afd117e8672598d99e1e463a33379a
https://doaj.org/article/ee9b3d5b06d7487a88a1aa89b695a63a
https://doaj.org/article/ee9b3d5b06d7487a88a1aa89b695a63a
Autor:
Michael Alifrangis, Sidsel Nag, Mette L. Schousboe, Deus S. Ishengoma, John Lusingu, Hirva Pota, Reginald A. Kavishe, Richard Pearce, Rosalynn Ord, Caroline Lynch, Seyoum Dejene, Jonathan Cox, John Rwakimari, Daniel T.R. Minja, Martha M. Lemnge, Cally Roper
Publikováno v:
Emerging Infectious Diseases, Vol 20, Iss 8, Pp 1280-1286 (2014)
Super-resistant Plasmodium falciparum threatens the effectiveness of sulfadoxine–pyrimethamine in intermittent preventive treatment for malaria during pregnancy. It is characterized by the A581G Pfdhps mutation on a background of the double-mutant
Externí odkaz:
https://doaj.org/article/517181b53a6f4e038e0639a57e65db56