Zobrazeno 1 - 10
of 50
pro vyhledávání: '"John, Lew"'
Publikováno v:
The FASEB Journal. 35
Author(s): Lam, Yi-Li | Advisor(s): Lew, John | Abstract: One of the hallmarks of Alzheimer’s disease is pathological tau aggregation. We previously reported that cinnamaldehyde, found in cinnamon, could inhibit tau aggregation in vitro, by reactin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5568fcd2bb48837bce9379ff0d4f5708
https://doi.org/10.1096/fasebj.2021.35.s1.01780
https://doi.org/10.1096/fasebj.2021.35.s1.01780
Autor:
Antoine Jean-Marie Viallet, Navin Budhiraja, Durga Prasad Muni, Suman Roy, Yeung Tack Yan John John Lew Chiang
Publikováno v:
CODS
Application development and maintenance is a good example of Information Technology Infrastructure Library (ITIL) services in which a sizable volume of tickets are raised everyday for different issues to be resolved in order to deliver uninterrupted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34a3c3d16778c81e84f0dfd32a933477
https://doi.org/10.1145/3041823.3041831
https://doi.org/10.1145/3041823.3041831
Autor:
Shu-Chin Huang, John Lew Cox
Publikováno v:
Universal Access in the Information Society. 15:219-236
The issue of narrowing the digital gap for disadvantaged people has been widely discussed. Yet, the study of how to enable low-income people and homeless wanderers to access computers and the Internet, thereby enabling their upward movement in societ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b963ca8c25c188a0a70e6d64670bda1
https://doi.org/10.1007/s10209-014-0379-7
https://doi.org/10.1007/s10209-014-0379-7
Autor:
Piotrowski, Chris1, Cox, John Lew1
Publikováno v:
Education. Summer2004, Vol. 124 Issue 4, p713-716. 4p. 2 Charts.
Publikováno v:
Proceedings of the National Academy of Sciences. 109:20041-20046
Cyclin-dependent kinase 5(CDK5) in complex with its activator, p35 (protein of 35 kDa), is essential for early neurodevelopment in mammals. However, endogenous cleavage of p35 to p25 is associated with neuron death and neurodegenerative disease. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e47fa31c6cde0860b10e9ab1296c612
https://doi.org/10.1073/pnas.1212914109
https://doi.org/10.1073/pnas.1212914109
Autor:
D. Michael Ando, John Lew, Daryl A. Taketa, Hongjun Zhou, Dylan W. Peterson, Fredrick W. Dahlquist
Publikováno v:
Proceedings of the National Academy of Sciences. 107:2884-2889
CDK5/p35 is a cyclin-dependent kinase essential for normal neuron function. Proteolysis of the p35 subunit in vivo results in CDK5/p25 that causes neurotoxicity associated with a number of neurodegenerative diseases. Whereas the mechanism by which co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3941147c6997e4da2818b6475e9c0570
https://doi.org/10.1073/pnas.0912718107
https://doi.org/10.1073/pnas.0912718107
Autor:
John Lew
Publikováno v:
Textbook of Endocrine Surgery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70fe048de39da927cc6dcde3c1547e7c
https://doi.org/10.5005/jp/books/12798_67
https://doi.org/10.5005/jp/books/12798_67
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 113, iss 2
Protein aggregation plays a critical role in the pathogenesis of neurodegenerative diseases, and the mechanism of its progression is poorly understood. Here, we examine the structural and dynamic characteristics of transiently evolving protein aggreg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68bfd51c9cea8cb135ec024cdd353fdc
https://pubmed.ncbi.nlm.nih.gov/26712030
https://pubmed.ncbi.nlm.nih.gov/26712030
Autor:
Dylan W. Peterson, Donald J. Graves, John Lew, Francesca Scaramozzino, Patrick Farmer, John T. Gerig
Publikováno v:
Biochemistry. 45:3684-3691
Alzheimer's disease most closely correlates with the appearance of the neurofibrillary tangles (NFTs), intracellular fibrous aggregates of the microtubule-associated protein, tau. Under native conditions, tau is an unstructured protein, and its physi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1758462ba3d2221163b89f6b239b8fe3
https://doi.org/10.1021/bi052167g
https://doi.org/10.1021/bi052167g
Publikováno v:
American Journal of Veterinary Research. 66:2006-2011
Objective—To assess antiulcerogenic properties of 3 dietary oils. Animals—8 healthy adult mares. Procedure—A protocol to induce gastric ulcers was used and included 240 mL of water plus corn oil, refined rice bran oil, or crude rice bran oil ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a74fd438a409a56ad38a44eab76be57
https://doi.org/10.2460/ajvr.2005.66.2006
https://doi.org/10.2460/ajvr.2005.66.2006